Tolfi Tablet

Maa: Bangladesh

Kieli: englanti

Lähde: DGDA (Directorate General of Drug Administration)

Aktiivinen ainesosa:

Tolfenamic Acid

Saatavilla:

Benham Pharmaceuticals Ltd.

INN (Kansainvälinen yleisnimi):

Tolfenamic Acid

Annos:

200 mg

Lääkemuoto:

Tablet

Pakkausseloste

TOLFI
Tolfenamic Acid
COMPOSITION:
Each tablet contains Tolfenamic Acid BP 200 mg.
DESCRIPTION:
Tolfenamic Acid is an NSAID with anti-infla matory, analgesic and
antipyretic effects. It is a
prostaglandin synthesis inhibitor and a leukotriene synthesis
inhibitor. Indications: Acute migraine.
DOSAGE AND ADMINISTRATION:
FOR ACUTE ATTACKS: 200 mg when the first symptoms of migraine appear.
The treatment can be
repeated once after 1-2 hours if a satisfactory response is not
obtained.
USE IN CHILDREN: A pediatric dosage regimen has not yet been
established.
USE IN ELDERLY: Normal adult dose.
USE IN PREGNANCY AND LACTATION :
IN PREGNANCY:
Reproduction studies in animals have not shown any signs of fetal
damage. Controlled studies in
pregnant women are not available. As is the case with the use of other
NSAIDs, tolfenamic acid
should not be given in the last trimester, due to risks of premature
closure of the ductus arteriosus
and prolonged parturition.
IN LACTATION:
Tolfenamic acid is excreted to such a very small extent in mothers'
milk that it should be without
risk to the breast-feed baby.
SIDE EFFECTS:
Tolfenamic Acid is well tolerated at the recommended dosage and seldom
causes side effects which
include diarrhea, nausea, epigastric pain, vomiting, urticaria,
allergic skin reactions etc.
CONTRAINDICATIONS:
Active peptic ulceration. Significantly impaired kidney or liver
function. Tolfenamic Acid is
contraindicated in patients in whom attacks of asthma, urticaria or
acute rhinitis are precipitated by
aspirin or other non-steroidal anti-inflammatory agents.
DRUG INTERACTIONS :
ANTICOAGULANTS : In patients treated with anticoagulants, close
monitoring of blood coagulation is
recommended.
DIURETICS : The effect of loop diuretics may be reduced.
LITHIUM : The effect of lithium may be increased.
SPECIAL PRECAUTIONS FOR USE :
As is the case with other NSAIDs, tolfenamic acid should be used with
caution in patients with a
history of gastrointestinal ulceration, or impaired liver or kidney
function.
PRECLINICAL SAFETY DATA