Sodium Chloride and Glucose IV Infusion

Maa: Australia

Kieli: englanti

Lähde: Department of Health (Therapeutic Goods Administration)

Aktiivinen ainesosa:

Sodium chloride; Glucose - anhydrous; Glucose (anhydrous)

Saatavilla:

Fresenius Kabi Australia Pty Limited

luokka:

Medicine Registered

Valmisteyhteenveto

Sodium Chloride and Glucose IV Infusion 
Product Information 

NaCl Glucose PI Amended 080915 
 Page 1 of  8 
Baxter 

SODIUM CHLORIDE (%) AND GLUCOSE (%)  
INTRAVENOUS INFUSION BP 

NAME OF THE DRUG 

Sodium Chloride (%) and Glucose (%) Intravenous Infusion BP  

Composition of the active ingredients: Glucose (anhydrous) and
Sodium Chloride in 
water for injection. The chemical name of glucose is
D-(+) glucopyranose.  Molecular 
formulae of glucose and sodium chloride is C
6
H
12
O
6,
 and NaCl, respectively. 

Chemical Structure:   

DESCRIPTION 

Glucose is a monosaccharide, having physical characteristics as
a white crystal or 
granular powder and freely soluble in water.  Sodium chloride
occurs as a colourless or 
white crystal and is freely soluble in water. 

The Sodium Chloride (%) and
Glucose (%) Intravenous Infusion preparations are a 
sterile, nonpyrogenic solution.  The concentrations of
the active ingredients dissolved in a 
litre of water for injection are shown in Table 1
(see Presentation).  They do not contain 
an antimicrobial agent or added buffer and have a pH
of 3.5 - 6.5.  They are iso-osmotic 
as indicated by their osmolarity shown in Table 1, except
glucose (5.0%) in sodium 
chloride (0.9%) with Osmolarity of 585.0 mOsmol/L,
and glucose (10%) in sodium 
chloride (0.22%) with osmolarity of 630.0 mOsmol/L. 

PHARMACOLOGY 

Mechanism of Action: 
Glucose is readily metabolised into carbon dioxide and water, with
a release of energy.  
As such, an administration of a glucose solution either by oral or
parenteral route 
provides water for body hydration as well as energy (see Table 1
for conversion to 
kJoules unit).  In addition, it may reduce catabolic loss of
nitrogen from the body and aid 
in prevention of depletion of liver glycogen.  That is, in
the absence of glucose, amino 
acids undergo deam