NEULEPTIL CAPSULE

Maa: Kanada

Kieli: englanti

Lähde: Health Canada

Aktiivinen ainesosa:

PERICIAZINE

Saatavilla:

SEARCHLIGHT PHARMA INC

ATC-koodi:

N05AC01

INN (Kansainvälinen yleisnimi):

PERICIAZINE

Annos:

10MG

Lääkemuoto:

CAPSULE

Koostumus:

PERICIAZINE 10MG

Antoreitti:

ORAL

Kpl paketissa:

15G/50G

Prescription tyyppi:

Prescription

Terapeuttinen alue:

PHENOTHIAZINES

Tuoteyhteenveto:

Active ingredient group (AIG) number: 0106194001; AHFS:

Valtuutuksen tilan:

APPROVED

Valtuutus päivämäärä:

2000-10-17

Valmisteyhteenveto

PRODUCT MONOGRAPH
PR
NEULEPTIL
_PERICIAZINE CAPSULES _
_ _
_PERICIAZINE ORAL DROPS _
_ _
_ _
_ _
_ _
PSYCHOTROPIC AGENT
Searchlight Pharma Inc.
1600 Notre-Dame West, suite 312
Montreal, Quebec
H3J 1M1
Date of Preparation:
JAN 26, 2023
Submission Control No.: 271076
1
PR
NEULEPTIL®
_PERICIAZINE CAPSULES _
_PERICIAZINE ORAL DROPS _
PSYCHOTROPIC AGENT
ACTION
Periciazine is a phenothiazine of the piperidine group. It has been
shown to reduce pathologic
arousal and affective tension in some psychotic patients, while the
symptoms of abnormal mental
integration are relatively unaffected.
It is a sedative phenothiazine with weak antipsychotic properties. It
also has adrenolytic,
anticholinergic metabolic and endocrine effects, and an action on the
extrapyramidal system.
Like other phenothiazines, it is presumed to act principally in the
subcortical areas, by producing
what has been described as a central adrenergic blockade.
INDICATIONS
As adjunctive medication in some psychotic patients, for the control
of residual prevailing
hostility, impulsiveness and aggressiveness.
CONTRAINDICATIONS
Circulatory collapse, altered states of consciousness or comatose
states, particularly when they
are due to intoxication with central depressant drugs such as alcohol,
hypnotics, analgesics,
narcotics, etc. It should also not be administered in association with
spinal or regional anesthesia.
Periciazine is contraindicated in patients with a history of blood
dyscrasias, liver disease or
hypersensitivity related to other phenothiazines.
WARNINGS
Geriatrics and Debilitated Patients: Particular care should be
exercised when periciazine is given
to elderly or debilitated patients as some appear to be unduly
sensitive to the effects of the drug.
Elderly Patients with Dementia: Elderly patients with dementia-related
psychosis treated with
antipsychotic drugs are at an increased risk of death. Analyses of
seventeen placebo-controlled
trials (modal duration of 10 weeks), largely in patients taking
atypical antipsychotic drugs,
revealed a risk o