Maa: Uusi-Seelanti
Kieli: englanti
Lähde: Medsafe (Medicines Safety Authority)
Methylprednisolone sodium succinate 1326mg equivalent to 1000 mg Methylprednisolone;
Pfizer New Zealand Limited
Methylprednisolone sodium succinate 1326 mg (Equiv to 1000 mg Methylprednisolone)
1000 mg
Powder for injection
Active: Methylprednisolone sodium succinate 1326mg equivalent to 1000 mg Methylprednisolone Excipient: Dibasic sodium phosphate Monobasic sodium phosphate
Vial, glass, Powder, 1000 mg
Prescription
Prescription
Sicor (Societa Italiana Corticosteroidi) Srl
Package - Contents - Shelf Life: Vial, glass, Powder - 1000 mg - 24 months from date of manufacture stored at or below 25°C
1990-07-02
Data Sheet – New Zealand Hosp 2 1 METHYLPREDNISOLONE SODIUM SUCCINATE POWDER FOR INJECTION PRESENTATION Methylprednisolone Sodium Succinate Powder for Injection is a sterile lyophilised powder for injection containing 500 mg or 1000 mg of Methylprednisolone as the sodium succinate. It also contains 6.4 mg sodium acid phosphate and 69.8 mg sodium phosphate or 12.8 mg sodium acid phosphate and 139.6 mg sodium phosphate. USES _ACTIONS _ Methylprednisolone in the form of methylprednisolone sodium succinate is a potent synthetic corticosteroid. Its anti-inflammatory potency is greater than prednisolone in the ratio of 5 to 4. It has only minimal mineralocorticoid properties and has less tendency than prednisolone to induce sodium and water retention. It influences carbohydrate, protein, fat and purine metabolism, electrolyte and water balance, and the functional capacities of the cardiovascular system, the kidney, the skeletal muscle, nervous system and other organs and tissues. It exerts a suppressive effect on the immune response. _PHARMACOKINETICS _ Methylprednisolone sodium succinate for injection, is rapidly and extensively hydrolysed _in vivo _by cholinesterases to free methylprednisolone. _INDICATIONS _ Methylprednisolone sodium succinate may be used in conditions in which a rapid, intense glucocorticoid effect is required. ENDOCRINE DISORDERS • Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoid supplementation is of particular importance). • Acute adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; mineralocorticoid supplementation may be necessary, particularly when synthetic an Lue koko asiakirja