Maa: Australia
Kieli: englanti
Lähde: Department of Health (Therapeutic Goods Administration)
Heparin sodium
HEPARIN INJECTION CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Heparin Injection. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you using Heparin Injection against the benefits this medicine is expected to have for you. This medicine is likely to be used while you are at the clinic or in hospital. If possible, please read this leaflet carefully before this medicine is given to you. In some cases this leaflet may be given to you after the medicine has been used. IF YOU HAVE ANY CONCERNS ABOUT USING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET. You may need to read it again. WHAT HEPARIN INJECTION IS USED FOR Heparin Injection belongs to a group of medicines known as anticoagulants. Anticoagulants work by decreasing the clotting ability of your blood and help stop clots forming in the blood vessels. Anticoagulants are sometimes called "blood thinners", although they do not actually thin the blood. Heparin will not dissolve blood clots that have already formed, but it may prevent any clots that have already formed from becoming larger and causing serious problems. Heparin Injection is used for prevention and treatment of diseases caused by blood clots such as in certain blood vessel, heart and lung conditions. It is also used to prevent blood clots from forming during surgery, dialysis or blood transfusions. Heparin Injection may be used for the treatment of other conditions that are not mentioned above. Your doctor will be able to tell you about the specific condition for which you have been prescribed Heparin Injection. This medicine is available only with a doctor's prescription. BEFORE YOU ARE GIVEN HEPARIN INJECTION _WHEN YOU MUST NOT BE GIVEN_ _IT_ DO NOT USE HEPARIN INJECTION IF YOU: • have an allergy to heparin or pork products • have, or may have, a bleeding disease Lue koko asiakirja
Version: pfphepai11012 Supersedes: pfphepai10611 Page 1 of 13 PRODUCT INFORMATION HEPARIN INJECTION HEPARIN SODIUM INJECTION (PORCINE MUCOUS) NAME OF THE MEDICINE Heparin sodium BP Heparin is a heterogeneous group of straight-chain anionic mucopolysaccharides, called glycosaminoglycans, possessing anticoagulant properties. It is composed of polymers of alternating derivations of α-D-glucosamido (_N_-sulfated _O_-sulfated or _N_-acetylated) and _O_- sulfated uronic acid (α-L-iduronic acid or β-D-glucuronic acid). HEPARIN CAS REGISTRY NUMBER IS 9005-49-6. DESCRIPTION Heparin sodium is a preparation containing the sodium salt of a sulphated glucosaminoglycan present in mammalian tissues. It is prepared from the lungs or from the intestinal mucosae of pigs. Heparin sodium is a white or almost white powder, moderately hygroscopic, freely soluble in water. Heparin Injection is a clear, colourless to straw coloured, sterile, preservative-free solution containing Heparin Sodium BP (porcine mucous) in Water for Injections BP. PHARMACOLOGY CLASS OF DRUG Anticoagulant. MECHANISM OF ACTION Heparin is a naturally occurring mucopolysaccharide with _in vitro_ and _in vivo_ anticoagulant activity. Heparin inhibits reactions that lead to the clotting of blood and the formation of fibrin clots both _in vitro_ and _in vivo_. Heparin acts at multiple sites in the normal coagulation system. Small amounts of heparin in combination with antithrombin III (heparin cofactor) can inhibit thrombosis by inactivating activated Factor X and inhibiting the conversion of prothrombin to thrombin. Once active thrombosis has developed, larger Lue koko asiakirja