Maa: Malesia
Kieli: englanti
Lähde: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CLOXACILLIN SODIUM
DYNAPHARM (M) SDN BHD
CLOXACILLIN SODIUM
100 Capsule Capsules; 500 Capsule Capsules; 1000 Capsule Capsules
DYNAPHARM (M) SDN BHD
Consumer Medication Information Leaflet (RiMUP) DYNA CLOXACILLIN CAPSULE Cloxacillin Sodium (250mg, 500mg) Page 1 of 2 What is in this leaflet 1. What Dyna Cloxacillin Capsule is used for 2. How Dyna Cloxacillin Capsule works 3. Before you use Dyna Cloxacillin Capsule 4. How to use Dyna Cloxacillin Capsule 5. While you are using it 6. Side effects 7. Storage and Disposal of Dyna Cloxacillin Capsule 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision What Dyna Cloxacillin Capsule is used for Dyna Cloxacillin Capsule is used to treat infections caused by resistant bacteria, including - Infections of skin and soft tissues - Bones and joints - Respiratory tract and urinary tract - Otitis media - Inflammation on the heart's inner lining - Blood poisoning - Inflammation of the membranes surrounding brain and spinal cord. How Dyna Cloxacillin Capsule works Cloxacillin is a bactericidal antibiotic which inhibits bacterial cell wall synthesis. Before you use Dyna Cloxacillin Capsule - When you must not use it Do not take Dyna Cloxacillin Capsule if you have hypersensitive to Cloxacillin or a history of allergic to Penicillin group of drugs. If a skin rash occurs, treatment should be discontinued. Pregnancy and lactation Do not take Dyna Cloxacillin Capsule if you are pregnant, trying to get pregnant or think you may be pregnant. Do not take Dyna Cloxacillin Capsule if you are breast-feeding. Ask your doctor or pharmacist for advice before taking any medicine. - Before you start use it Tell your doctor if you have impaired kidney function, hypersensitive to any other Penicillin or Cephalosporin or Penicillamine. - Taking other medicines Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. Probenecid impairs kidney excretion and reduces anticoagulant effect. How to use Dyna Cloxacillin Capsule - How much to use Adult: 250 – 500 mg every 6 hours daily. Children: 50-100 mg per kg bod Lue koko asiakirja
DYNA CLOXACILLIN CAPSULE DESCRIPTION CONTENT DYNA CLOXACILLIN CAPSULE 250MG MAL19930225AZ CAPSULE Capsule Colour : Medium Orange/Black Capsule Size : # 2 Granules Colour : White Each capsule contains: Cloxacillin Sodium equivalent to Cloxacillin 250 mg DYNA CLOXACILLIN CAPSULE 500MG MAL07090901AZ CAPSULE Capsule Colour : Medium Amethyst/Black Capsule Size : # 0 Granules Colour : White Marking : “DYNA” & Logo Each capsule contains: Cloxacillin Sodium equivalent to Cloxacillin 500 mg PHARMACODYNAMICS: Cloxacillin is a bactericidal antibiotic which inhibits bacterial cell wall synthesis, probably by acylation of membrane-bound transpeptidase enzymes. This prevents cross-linkage of peptidoglycan chains which is necessary for bacterial cell wall strength and rigidity. Also, cell division and growth are inhibited and lysis of susceptible bacteria frequently occurs. Rapidly dividing bacteria are most susceptible to penicillin group of antibiotics. Cloxacillin is resistant to staphylococcal penicillinase. It has an antibacterial spectrum similar to that of methicillin. PHARMACOKINETICS: Cloxacillin sodium is incompletely absorbed from the gastrointestinal tract after oral administration, and absorption is further reduced by the presence of food in the stomach. After an oral dose of 500 mg, a peak plasma concentration of 7 to 14 g per ml is obtained in fasting subjects in 1 to 2 hours. Absorption is more complete when given by intramuscular injection and peak plasma concentrations of about 15 g per ml have been observed 30 minutes after a dose of 500 mg. Doubling the dose can double the plasma concentration. About 94% of cloxacillin in the circulation are bound to plasma proteins. Cloxacillin has been reported to have a plasma half-life of approximately 0.5 hours in healthy subjects. The half-life is prolonged in neonates. Cloxacillin diffuses across the placenta into the foetal circulation and is excreted in breast milk. There is little diffusion into the CFS except when the meninges are inflamed. Therapeutic c Lue koko asiakirja