Maa: Yhdysvallat
Kieli: englanti
Lähde: NLM (National Library of Medicine)
dexamethasone phosphate (UNII: 2BP70L44PR) (dexamethasone - UNII:7S5I7G3JQL)
Cardinal Health
dexamethasone phosphate
dexamethasone phosphate 4 mg in 1 mL
PRESCRIPTION DRUG
Abbreviated New Drug Application
DEXAMETHASONE SODIUM PHOSPHATES- DEXAMETHASONE PHOSPHATE INJECTION, SOLUTION CARDINAL HEALTH ---------- DEXAMETHASONE SODIUM PHOSPHATE INJECTION, USP RX ONLY DESCRIPTION Dexamethasone Sodium Phosphate Injection, USP is a water-soluble inorganic ester of dexamethasone. It occurs as a yellow crystalline powder, is odorless or has a slight odor of alcohol, is exceedingly hygroscopic, and is freely soluble in water. Dexamethasone Sodium Phosphate Injection, USP is a synthetic adrenocortical steroid anti-inflammatory drug. It has the following structural formula: Dexamethasone Sodium Phosphate Injection, USP C H FNa O P, has a molecular weight of 516.41 and the chemical name 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21- (dihydrogen phosphate) disodium salt. Dexamethasone Sodium Phosphate Injection, USP 4 mg/mL is a sterile solution for intravenous, intramuscular, intra-articular, intralesional and soft tissue administration. Each mL of the injection contains the following components: CLINICAL PHARMACOLOGY Dexamethasone Sodium Phosphate Injection, USP has a rapid onset but short duration of action when compared with less soluble preparations. Because of this, it is suitable for the treatment of acute disorders responsive to adrenocortical steroid therapy. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs, including dexamethasone, are primarily used for their potent anti-inflammatory effects in disorders of many organ systems. 22 28 2 8 Dexamethasone Sodium Phosphate (equivalent to 4 mg of Dexamethasone Phosphate)...4.37 mg Sodium Sulfite.............................................................1 mg Benzyl Alcohol.............................................................10 mg Sodium Citrate.............................................................for isotonicity Water for Injection.................................................... Lue koko asiakirja