CYTOMEL- liothyronine sodium tablet

Maa: Yhdysvallat

Kieli: englanti

Lähde: NLM (National Library of Medicine)

Aktiivinen ainesosa:

LIOTHYRONINE SODIUM (UNII: GCA9VV7D2N) (LIOTHYRONINE - UNII:06LU7C9H1V)

Saatavilla:

Physicians Total Care, Inc.

INN (Kansainvälinen yleisnimi):

LIOTHYRONINE SODIUM

Koostumus:

LIOTHYRONINE SODIUM 5 ug

Antoreitti:

ORAL

Prescription tyyppi:

PRESCRIPTION DRUG

Käyttöaiheet:

Thyroid hormone drugs are indicated: - As replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. This category includes cretinism, myxedema and ordinary hypothyroidism in patients of any age (pediatric patients, adults, the elderly), or state (including pregnancy); primary hypothyroidism resulting from functional deficiency, primary atrophy, partial or total absence of thyroid gland, or the effects of surgery, radiation, or drugs, with or without the presence of goiter; and secondary (pituitary) or tertiary (hypothalamic) hypothyroidism (see WARNINGS ). As replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. This category includes cretinism, myxedema and ordinary hypothyroidism in patients of any age (pediatric patients, adults, the elderly), or state (including pregnancy

Tuoteyhteenveto:

Cytomel (liothyronine sodium) Tablets: 5 mcg 25 mcg Store between 15° and 30°C (59° and 86°F). Prescribing Information as of March 2004. Manufactured by: King Pharmaceuticals, Inc., Bristol, TN 37620 Relabeling and Repackaging by: Physicians Total Care, Inc. Tulsa, OK       74146

Valtuutuksen tilan:

New Drug Application

Valmisteyhteenveto

CYTOMEL - LIOTHYRONINE SODIUM TABLET
PHYSICIANS TOTAL CARE, INC.
----------
Drugs with thyroid hormone activity, alone or together with other
therapeutic agents, have been
used for the treatment of obesity. In euthyroid patients, doses within
the range of daily hormonal
requirements are ineffective for weight reduction. Larger doses may
produce serious or even
life-threatening manifestations of toxicity, particularly when given
in association with
sympathomimetic amines such as those used for their anorectic effects.
DESCRIPTION
Thyroid hormone drugs are natural or synthetic preparations containing
tetraiodothyronine (T ,
levothyroxine) sodium or triiodothyronine (T , liothyronine) sodium or
both. T and T are produced in
the human thyroid gland by the iodination and coupling of the amino
acid tyrosine. T contains four
iodine atoms and is formed by the coupling of two molecules of
diiodotyrosine (DIT). T contains three
atoms of iodine and is formed by the coupling of one molecule of DIT
with one molecule of
monoiodotyrosine (MIT). Both hormones are stored in the thyroid
colloid as thyroglobulin.
Thyroid hormone preparations belong to two categories: (1) natural
hormonal preparations derived from
animal thyroid, and (2) synthetic preparations. Natural preparations
include desiccated thyroid and
thyroglobulin. Desiccated thyroid is derived from domesticated animals
that are used for food by man
(either beef or hog thyroid), and thyroglobulin is derived from
thyroid glands of the hog. The United
States Pharmacopeia (USP) has standardized the total iodine content of
natural preparations. Thyroid
USP contains not less than (NLT) 0.17 percent and not more than (NMT)
0.23 percent iodine, and
thyroglobulin contains not less than (NLT) 0.7 percent of organically
bound iodine. Iodine content is
only an indirect indicator of true hormonal biologic activity.
Cytomel (liothyronine sodium) Tablets contain liothyronine
(L-triiodothyronine or LT ), a synthetic
form of a natural thyroid hormone, and is available as the sodium
salt