Maa: Yhdysvallat
Kieli: englanti
Lähde: NLM (National Library of Medicine)
Atropine Sulfate (UNII: 03J5ZE7KA5) (Atropine - UNII:7C0697DR9I)
Cardinal Health
Atropine Sulfate
Atropine Sulfate 0.4 mg in 1 mL
PRESCRIPTION DRUG
unapproved drug other
ATROPINE SULFATE- ATROPINE SULFATE INJECTION, SOLUTION CARDINAL HEALTH _Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been_ _approved by FDA. For further information about unapproved drugs, click here._ ---------- ATROPINE SULFATE 0.4 MG/ML INJECTION, USP 1 ML SINGLE DOSE VIAL DES CRIPTION Atropine Sulfate Injection, USP is a sterile, isotonic solution of Atropine Sulfate in Water for Injection q.s. Sodium Chloride added for isotonicity. pH adjusted with Sulfuric Acid. Preservative free. Atropine is a white crystalline alkaloid which may be extracted from belladonna root and hyoscyamine or may be produced synthetically. It is used in the form of atropine sulfate because this compound has much greater solubility in water. The structural formula of Atropine is as follows: Molecular Formula Molecular Weight C17H23NO3 289.37 CLINICAL PHARMACOLOGY Atropine has two actions. The most important therapeutic action is the inhibition of smooth muscle and glands innervated by postganglionic cholinergic nerves. Atropine also has central-nervous system activity, which may be stimulating or depressing depending upon the dose. INDICATIONS AND USAGE 1. In the treatment of parkinsonism. Rigidity and tremor relieved by the apparently selective depressant action. 2. In the gastrointestinal tract to relieve pylorospasm, hypertonicity of the small intestine and the hypermotility of the colon. 3. To relieve hypertonicity of the uterine muscle. 4. To relax the spasm of biliary and uretered colic and bronchial spasm. 5. To diminish the tone of the detrusor muscle of the urinary bladder in the treatment of urinary tract disorders. 6. To control the crying and laughing episodes in patients with brain lesions. 7. In cases of closed head injuries which cause acetylcholine to be released or to be present in cerebrospinal fluid which in turn causes abnormal EEG patterns, stupor and neurological signs. 8. In the management of peptic ulcer. 9. In anesthesia to control excessive salivation and Lue koko asiakirja