XYLOCAINE 2%

Riik: Austraalia

keel: inglise

Allikas: Department of Health (Therapeutic Goods Administration)

Toimeaine:

Lignocaine hydrochloride

Saadav alates:

AstraZeneca Pty Ltd

Klass:

Medicine Listed (Export Only)

Infovoldik

Xylocaine

/ Nurocain

Dental   
1(3)  
XYLOCAINE

DENTAL 
NUROCAIN

DENTAL 

Lignocaine hydrochloride 
___________________________________________________________________________  
CONSUMER MEDICINE INFORMATION 

Name of consumer  
Address of consumer              

__________________
WHAT IS IN THIS LEAFLET 
___________________________________________________________________  
XYLOCAINE, NUROCAIN and 
LIGNOCAINE are different names for 
the same medicine which is used as 
to stop pain during dental 
procedures.  It is only called  
XYLOCAINE DENTAL in this leaflet.  
The information about them is the 
same.  
This leaflet answers some of the 
common questions people ask about 
XYLOCAINE DENTAL.  It does not 
contain all the information that is 
known about XYLOCAINE DENTAL.  
It does not take the place of talking 
to your dentist or pharmacist.  
All medicines have risks and 
benefits.  Your dentist will have 
weighed the risks of you being 
given XYLOCAINE DENTAL against the 
benefits they expect it will have for 
you.  
IF YOU HAVE ANY CONCERNS ABOUT 
BEING GIVEN THIS MEDICINE, ASK 
YOUR DENTIST OR PHARMACIST.  
KEEP THIS LEAFLET.  You may need to 
read it again. 
__________________
WHAT XYLOCAINE 
DENTAL IS FOR 
___________________________________________________________________  
XYLOCAINE DENTAL is used to 
prevent or  relieve pain during 
dental procedures, but it will not put 
you to sleep.  
XYLOCAINE DENTAL belongs to a 
group of medicines called local 
anaesthetics.    It is injected into the 
mouth where it makes the nerves 
unable to pass messages to the 
brain.  
Depending on the amount used, 
XYLOCAINE DENTAL will either totally 
stop pain or will cause a partial loss 
of feeling.    
XYLOCAINE DENTAL is often used 
with adrenaline to make it last 
longer.  Adrenaline makes the 
blood vessels at the site of injection 
narrower, which means you bleed 
less and it

Toote omadused

Xylocaine/Nurocain/Lignocaine Dental Product Information 
1 (9) 
C:\Documents and Settings\hraghib\Desktop\pending work\Pi & CMI
submission TGA\Drafts\Xylocaine PI_tracked 
changes_ct_13june03.doc 22/12/99 11:24 
TGA letter of approval March 27, 1987 
Safety changes February 3, 1999 
Non-Safety changes approved 10 November 1999   
XYLOCAINE

/NUROCAIN

/LIGNOCAINE DENTAL  
PRODUCT INFORMATION 
(Lignocaine hydrochloride)   
(Injection solutions for the production  
of local anaesthesia in dental procedures)   
NAME OF DRUG  
The  active  ingredient  in  XYLOCAINE,  NUROCAIN  and  LIGNOCAINE  solutions  is 
2-Diethylaminoaceto-2',6'-xylidide hydrochloride.  
The Australian Approved Name is lignocaine hydrochloride.  
DESCRIPTION  
Lignocaine is classed as a membrane stabilising agent, and is a local anaesthetic of 
the amide type.  Lignocaine solutions are available with and
without adrenaline.  
Plain  aqueous  solutions  of  lignocaine  hydrochloride  have  a  pH  of  5.0-7.0 (approx.); 
lignocaine solutions with adrenaline have a pH of 3.0-5.0 (approx.).  Lignocaine base 
has a pKa of 7.85 (25oC) and a molecular weight of 234.3.  
PHARMACOLOGY  
Lignocaine  stabilises  the  neuronal  membrane  and  reversibly  prevents  the  initiation 
and conduction of nerve impulses thereby producing local
anaesthesia.  
The onset and duration of anaesthesia depend on the route of administration and the 
dosage  (volume  and  concentration)  employed.   The  addition  of  adrenaline  reduces 
the  rate  of  absorption  of  lignocaine  from  the  site of  injection,  thereby increasing the 
duration of action.  
Lignocaine  is  metabolised  mainly  in  the  liver  and  excreted  via  the  kidneys.  
Approximately  90%  of  administered  lignocaine  is  excreted  in  the  form  of  various