Tylosina 66.8% ww Water Soluble Powder

Riik: Malaisia

keel: inglise

Allikas: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Toimeaine:

TYLOSIN TARTRATE

Saadav alates:

F.E. VENTURE SDN. BHD.

INN (Rahvusvaheline Nimetus):

TYLOSIN TARTRATE

Ühikuid pakis:

150 gm

Valmistatud:

Nam Pharma Sdn. Bhd.

Toote omadused

TYLOSINA 66.8% W/W WATER SOLUBLE POWDER (FOR VETERINARY USE ONLY)
COMPOSITION
Tylosin Tartrate ……………..……………… 668g
(Tylosin activity……………………………607g)
Excipients q.s.………………………….…….1000g
PRODUCT DESCRIPTION
It is a light yellow color powder.
PHARMACODYNAMICS
Tylosin is a macrolide antibiotic produced by a strain of _
Streptomyces fradiae_. It exerts its antimicrobial effect by
inhibiting protein
synthesis of susceptible micro-organisms.
The tylosin spectrum of activity includes Gram-positive bacteria
including _Clostridium perfringens_ and some Gram-negative strains
such as
Pasteurella and Mycoplasma spp_. _at concentrations of 16µg/ml or
less.
PHARMACOKINETICS
Absorption: Tylosin reaches maximal blood levels between 1 and 3 hours
after an oral dose. Minimal or no blood levels remain 24 hours
after an oral dose.
Distribution: After oral doses were given to pigs, tylosin was found
in all tissues, between 30 minutes and two hours after administration,
except for the brain and spinal cord.
Biotransformation and Elimination: It has been shown that most of the
material which is excreted is to be found in the faeces and consists
of
tylosin (factor A), relomycin (factor D) and dihydrodesmycosin.
INDICATIONS
Chickens:
For the control of _Mycoplasma synoviae_ airsacculitis and _Mycoplasma
gallisepticum_ S6 in chickens. In the field tylosin has also proved
useful in reducing the level of infection following stress associated
with live vaccination.
As an aid in the control of outbreaks of necrotic enteritis in
chickens caused by _Clostridium perfringens_.
Pigs:
For the prevention and control of enzootic pneumonia, and scours
caused by organisms (e.g. _Lawsonia intracellularis_) sensitive to
tylosin
CONTRA-INDICATIONS
Do not leave or dispose of water containing tylosin tartrate where it
may be accessible to either animals not under treatment or to
wildlife.
Do not use in known cases of hypersensitivity to tylosin or other
macrolides.
MODE OF ADMINISTRATION
Oral