Rhotarsin 20WSP Powder for Oral Solution 20%ww

Riik: Malaisia

keel: inglise

Allikas: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Toimeaine:

TYLOSIN TARTRATE

Saadav alates:

Rhone Ma Malaysia Sdn Bhd

INN (Rahvusvaheline Nimetus):

TYLOSIN TARTRATE

Ühikuid pakis:

1kg kg

Valmistatud:

Rhone Ma Malaysia Sdn Bhd

Toote omadused

RHOTARSIN 20 WSP
Powder for Oral Solution
20% w/w
COMPOSITION: Tylosin tartrate 24.5% w/w (equivalent to Tylosin 20%
w/w).
PRODUCT DESCRIPTION: White to off white powder.
PHARMACODYNAMICS: Tylosin is a macrolide antibiotic produced by a
strain of _Streptomyces fradiae_. It
exerts its antimicrobial effect by inhibiting protein synthesis of
susceptible micro-organisms. The
tylosin spectrum of activity includes Gram-positive bacteria including
_Clostridium perfringens_ and
some Gram-negative strains such as _Pasteurella_ and _Mycoplasma spp.
_ at concentrations of 16µg/ml
or less.
PHARMACOKINETICS: Absorption: Tylosin reaches maximal blood levels
between 1 and 3 hours after
an oral dose. Minimal or no blood levels remain 24 hours after an oral
dose. Distribution: After oral
doses were given to pigs, tylosin was found in all tissues, between 30
minutes and two hours after
administration, except for the brain and spinal cord.
Biotransformation and Elimination: It has been
shown that most of the material which is excreted is to be found in
the faeces and consists of tylosin
(factor A), relomycin (factor D) and dihydrodesmycosin.
INDICATION: For the control of _Mycoplasma synoviae_, airsacculitis
caused by _Mycoplasma gallisepti-_
_cum_ in chickens and turkeys. Used as preventive measure to reduce
level of infections following
stress induced by live vaccination. As an aid in the control of
outbreaks of necrotic enteritis in
chickens caused by _Clostridium perfringens_. For prevention and
control of enzootic pneumonia, and
scours caused by organisms (e.g. _Lawsonia intracellularis_) sensitive
to tylosin, in pigs. For the control
of pneumonia in calves associated with mycoplasma and _Pasteurella
multocida_ sensitive to tylosin.
DOSAGE AND ADMINISTRATION: For oral administration.
Recommendations for use in chickens and turkeys:
Rhotarsin 20WSP is administered in the drinking water at a
concentration of 2.5g per litre.
For control of necrotic enteritis caused by _Clostridium perfingens_
in chicken, use at dose rate of 0.75