Riik: Ameerika Ühendriigid
keel: inglise
Allikas: NLM (National Library of Medicine)
PHENYLPROPANOLAMINE HYDROCHLORIDE (UNII: 8D5I63UE1Q) (PHENYLPROPANOLAMINE - UNII:33RU150WUN)
Pegasus Laboratories, Inc.
PHENYLPROPANOLAMINE HYDROCHLORIDE
PHENYLPROPANOLAMINE HYDROCHLORIDE 50 mg
ORAL
PRESCRIPTION
PROIN (phenylpropanolamine hydrochloride) is a sympathomimetic amine closely related to ephedrine. Phenylpropanolamine hydrochloride (PPA) is the nonproprietary designtion for benzenemethanol,α - (1-aminoethyl) - hydrochloride, (R*,S*) -, (±). The empirical formula is C9H13NO•HCL and the molecular weight is 187.67. It is a white crystalline compound having a slight aromatic odor. PPA is freely soluable in water and alcohol but is practically insoluable in ether, benzene and chloroform. The chemical structure of phenylpropanolamine hydrochloride is:
PROIN is scored and contains 25, 50 or 75 mg phenylpropanolamine hydrochloride per tablet. PROIN is packaged in bottles containing 60 or 180 tablets. Approved by FDA under NADA # 141-324. PROIN ® is a registered trademark of Pegasus Laboratories, Inc.
New Animal Drug Application
PROIN 50- PHENYLPROPANOLAMINE HYDROCHLORIDE TABLET, CHEWABLE PEGASUS LABORATORIES, INC. ---------- FOR ORAL USE IN DOGS ONLY CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION: PROIN (phenylpropanolamine hydrochloride) is a sympathomimetic amine closely related to ephedrine. Phenylpropanolamine hydrochloride (PPA) is the nonproprietary designtion for benzenemethanol,α - (1-aminoethyl) - hydrochloride, (R*,S*) -, (±). The empirical formula is C9H13NO•HCL and the molecular weight is 187.67. It is a white crystalline compound having a slight aromatic odor. PPA is freely soluable in water and alcohol but is practically insoluable in ether, benzene and chloroform. The chemical structure of phenylpropanolamine hydrochloride is: INDICATION: PROIN is indicated for the control of urinary incontinence due to urethral sphincter hypotonus in dogs. DOSAGE AND ADMINISTRATION: The total recommended dosage for oral administration is 2 mg/kg (0.91 mg/lb) of body weight twice daily. PROIN is scored and dosage should be calculated in half-tablet increments. WARNINGS: Not for human use. Keep out of reach of children. Consult a physician in case of accidental ingestion by humans. PRECAUTIONS: PROIN may cause increased thirst; therefore, provide ample fresh water. Overdose has been associated with dogs chewing through closed bottles of PROIN and consuming multiple tablets. Therefore, it is important to store PROIN Chewable Tablets out of reach of dogs and other pets in a secured location. Use in dogs with incontinence due to a urinary tract infection will mask symptoms. PROIN is not effective in dogs with incontinence due to neurologic disease or malformations. PROIN may cause hypertension; therefore, use with caution in dogs with pre-existing heart disease, hypertension, liver disease, kidney insufficiency, diabetes, glaucoma, and conditions with a predilection for hypertension. Use with caution in dogs receiving sympathomimetic drugs, tricyclic antidepressants, or monoamine Lugege kogu dokumenti