CALCIUM CHLORIDE injection, solution

Riik: Ameerika Ühendriigid

keel: inglise

Allikas: NLM (National Library of Medicine)

Toimeaine:

CALCIUM CHLORIDE (UNII: M4I0D6VV5M) (CALCIUM CATION - UNII:2M83C4R6ZB, CHLORIDE ION - UNII:Q32ZN48698)

Saadav alates:

Hospira, Inc.

INN (Rahvusvaheline Nimetus):

CALCIUM CHLORIDE

Koostis:

CALCIUM CHLORIDE 100 mg in 1 mL

Manustamisviis:

INTRAVENOUS

Retsepti tüüp:

PRESCRIPTION DRUG

Näidustused:

10% Calcium Chloride Injection, USP is indicated (1) for the treatment of hypocalcemia in those conditions requiring a prompt increase in blood plasma calcium levels, (2) in the treatment of magnesium intoxication due to overdosage of magnesium sulfate and (3) to combat the deleterious effects of hyperkalemia as measured by electrocardiographic (ECG), pending correction of the increased potassium level in the extracellular fluid. 10% Calcium Chloride Injection, USP also may be used in cardiac resuscitation when weak or inadequate contractions return following defibrillation or when epinephrine injection has failed to strengthen myocardial contractions. Calcium chloride is contraindicated for cardiac resuscitation in the presence of ventricular fibrillation or in patients with the risk of existing digitalis toxicity. None known.

Toote kokkuvõte:

10% Calcium Chloride Injection, USP is supplied in single-dose containers as follows: NDC No. Container Size Needle Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.] Abboject® is a trademark of the Abbott group of companies LIFESHIELD® is the trademark of ICU Medical, Inc. and is used under license. Distributed by Hospira, Inc., Lake Forest, IL 60045 USA LAB-1241-2.0 Revised: 04/2018

Volitamisolek:

unapproved drug other

Toote omadused

CALCIUM CHLORIDE- CALCIUM CHLORIDE INJECTION, SOLUTION
HOSPIRA, INC.
_Disclaimer: This drug has not been found by FDA to be safe and
effective, and this labeling has not been_
_approved by FDA. For further information about unapproved drugs,
click here._
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10%
CALCIUM CHLORIDE
INJECTION, USP
100 MG/ML RX ONLY
REPRESENTS 27 MG (1.4 MEQ) CA
/ML
ABBOJECT SYRINGE
_A HYPERTONIC SOLUTION IN A 10 ML_
_UNIT OF USE SYRINGE FOR PROMPT_
_INTRAVENOUS INJECTION._
CAUTION: THIS SOLUTION MUST NOT BE INJECTED
INTRAMUSCULARLY OR SUBCUTANEOUSLY.
DESCRIPTION
10% Calcium Chloride Injection, USP is a sterile, nonpyrogenic,
hypertonic solution containing 100
mg (1.4 mEq/mL) of calcium chloride, dihydrate (1.4 mEq each of Ca
and Cl¯) in water for injection.
It is provided in a 10 mL Unit of Use Syringe to facilitate prompt
intravenous injection. The solution is
administered only by intravenous or intraventricular cavity injection
as a calcium replenisher.
The solution contains no bacteriostat, antimicrobial agent or added
buffer and is intended only for use as
a single-dose injection. As per USP testing, when diluted with water
for injection to make a 5%
solution, the pH of calcium chloride injection is 6.3 (5.5 to 7.5).
May contain hydrochloric acid and/or
sodium hydroxide for pH adjustment. The osmolar concentration is 2.04
mOsmol/mL (calc.). 10%
Calcium Chloride Injection, USP is oxygen sensitive.
Calcium Chloride, USP dihydrate is chemically designated CaCl
· 2H O (dihydrate) white, odorless
fragments or granules freely soluble in water.
CLINICAL PHARMACOLOGY
Calcium is the fifth most abundant element in the body and the major
fraction is in the bony structure.
Calcium plays important physiological roles, many of which are poorly
understood. It is essential for
the functional integrity of the nervous and muscular systems. It is
necessary for normal cardiac function
and is one of the factors that operates in the mechanisms involved in
the coagulation of blood.
Calcium chloride in water dissociates to provide calcium (Ca
)