Riik: Malaisia
keel: inglise
Allikas: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
MINOXIDIL
Abio Marketing Sdn Bhd
MINOXIDIL
60 ml
SINPHAR PHARM CO LTD
Consumer Medication Information Leaflet _(RiMUP)_ Page 1 of 3 pages AVOXIDIL TOPICAL SOLUTION 5%W/V Minoxidil 5%w/v WHAT IS IN THIS LEAFLET: a) What Avoxidil is used for b) How Avoxidil works c) Before you use Avoxidil d) How to use Avoxidil e) While you are using Avoxidil f) Side effects g) Storage and disposal of Avoxidil h) Product description i) Manufacturer j) Product Registration Holder k) Date of revision WHAT AVOXIDIL IS USED FOR The name of your medicine is Avoxidil Topical Solution 5%w/v (called ‘Avoxidil’ in this leaflet). Avoxidil contains a medicine called Minoxidil. Avoxidil is used to treat baldness and hair loss in men and women. It stimulates hair growth and stabilize hair loss in baldness and hair loss. HOW AVOXIDIL WORKS Its mechanism of action is not known. However, when applied topically, minoxidil has been shown to stimulate hair growth in individuals with problems of baldness and hair loss. It takes 4 months or more for hair to start growing and growth of new hair will stop upon discontinuation. Pre- treatment appearance will be restored within 3-4 months. BEFORE YOU USE AVOXIDIL WHEN YOU MUST NOT USE IT. Do not apply this medicine to other than your scalp. Do not use this medicine if you are: under the age of 18 allergic (hypersensitive) to Minoxidil, alcohol or propylene glycol. having hair loss caused by drug treatment. having total baldness or complete loss of all body hair. having unknown cause of hair loss, or it is sudden and unexpected. having HIGH BLOOD PRESSURE , even if it is not being treated. having any CONDITION THAT AFFECTS YOUR SCALP , including sunburn and psoriasis. having a SHAVED SCALP. using CREAMS, OINTMENTS OR LOTIONS used to treat scalp conditions having any kind of dressing or bandage on your scalp. BEFORE YOU START TO USE IT: This medicine is for external use only. Check with your doctor or pharmacist before taking this medicine: If you are unsure whether your scalp is normal and healthy. If you suffer from heart Lugege kogu dokumenti
AVOXIDIL TOPICAL SOLUTION 5 % W/V COMPOSITION Each ml contains: Minoxidil 50 mg PRODUCT DESCRIPTION A colorless to light yellowish clear liquid. INDICATION Avoxidil Topical Solution 50mg/ml spray is exclusively indicated for the treatment of alopecia androgenetica in males and females. Avoxidil Topical Solution 50mg/ml spray stimulates hair growth and stabilizes hair loss in patients with alopecia androgenetica. PHARMACOLOGICAL PROPERTIES ATC CODE: D11AX01 Pharmacotherapeutic group: Dermatological preparations containing minoxidil PHARMACODYNAMIC PROPERTIES _MECHANISM OF ACTION: _ The exact mechanism of action of minoxidil in the treatment of alopecia androgenetica is not known. However, when applied topically, minoxidil has been shown to stimulate hair growth in individuals with alopecia androgenetica. The onset of hair growth stimulation occurs approximately after 4 or more months of use and is variable among patients. Upon discontinuation of Avoxidil Topical Solution 50mg/ml, new hair growth stops and restoration of pretreatment appearance is expected within 3 -4 months. PHARMACOKINETIC PROPERTIES Following topical application, minoxidil is poorly absorbed from normal intact skin, with an average of 1.4% (range 0.3-4.5%) of the total applied dose ultimately reaching the systemic circulation. Therefore a 1 mL dose of Avoxidil Topical Solution 50mg/ml, delivering 50 mg minoxidil to the skin, would result in absorption of approximately 0.70 mg minoxidil. The effects of concomitant dermal diseases on absorption are unknown. Serum minoxidil levels resulting from topical administration of minoxidil are governed by the drug’s percutaneous absorption rate. Following cessation of topical dosing of minoxidil approximately 95% of systemically absorbed minoxidil is eliminated within 4 days. The metabolic biotransformation of minoxidil absorbed following topical application has not been fully determined. RECOMMENDED DOSAGE ROUTE OF ADMINISTRATION : For external use only. Use Avoxidil only as directed. Do not apply Avoxid Lugege kogu dokumenti