Riik: Austraalia
keel: inglise
Allikas: Department of Health (Therapeutic Goods Administration)
biperiden hydrochloride
Amdipharm Mercury Australia Pty Ltd
Medicine Registered
Registered
AKINETON ® _biperiden hydrochloride_ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about Akineton. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking Akineton against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT AKINETON IS USED FOR Akineton is used to treat symptoms of parkinsonism. The symptoms of parkinsonism include slow and unsteady movement, muscle stiffness and shaking (tremors). If untreated parkinsonism can cause difficulty in performing normal daily activities. Symptoms of parkinsonism can be caused by certain diseases of the brain affecting movement, such as Parkinson's disease. They can also be caused by some medicines that are used to treat certain mental conditions. It is believed the symptoms of parkinsonism are caused by a lack of dopamine, a naturally occurring chemical produced by certain brain cells. When not enough dopamine is present, acetylcholine which is another naturally occurring chemical produced by brain cells, can interfere with the regions of the brain that control muscle movement. Akineton blocks the effects of acetylcholine. In many patients, this reduces the symptoms of shaking and muscle stiffness. Akineton is also used to treat cramps that occur during the night. Akineton belongs to a group of medicines called anticholinergics. It is available as tablets. ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY AKINETON HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed Akineton for another reason. This medicine is available only with a doctor’s prescription. BEFORE YOU TAKE AKINETON _WHEN YOU MUST NOT TAKE IT_ DO NOT TAKE AKINETON IF YOU HAVE AN ALLERGY TO: • any medicine containing biperiden • any of the in Lugege kogu dokumenti
Page 1 of 6 PRODUCT INFORMATION AKINETON ® (BIPERIDEN HYDROCHLORIDE 2 MG TABLETS) NAME OF THE MEDICINE Non-proprietary name: biperiden hydrochloride Structural formula (biperiden): Chemical name (biperiden): α-5-norbornen-2-yl-α-phenyl-1-piperidine propanol Molecular weight: 311.5 (biperiden); 347.9 (biperiden hydrochloride) CAS number: 514-65-8 (biperiden); 1235-82-1 (biperiden hydrochloride) DESCRIPTION Biperiden is a white, crystalline, odourless powder, slightly soluble in water and alcohol. It is stable in air at ambient temperatures. Biperiden hydrochloride tablet 2 mg is equivalent to 1.8 mg biperiden. Biperiden tablets contain the following excipients: maize starch, calcium hydrogen phosphate dihydrate, microcrystalline cellulose, povidone, lactose monohydrate, purified talc, magnesium stearate, purified water and pregelatinised potato starch. INDICATIONS Akineton is indicated for the treatment of Parkinsonism, drug-induced extrapyramidal symptoms, pyramidal spasticity, closed craniocerebral trauma and post-concussion symptoms, trigeminal neuralgia and nocturnal cramps. CONTRAINDICATIONS Known hypersensitivity to biperiden hydrochloride or to any of the components in the medication, narrow angle glaucoma, mechanical stenosis of the gastrointestinal tract, in megacolon and in ileus. PRECAUTIONS Akineton should be administered with caution to patients with prostatic hypertrophy with accumulation of residual urine. Page 2 of 6 In a few cases, especially in patients with prostatic adenoma, Akineton may cause disturbances of micturition calling for a reduction of the dose, rarely anuria (antidote: carbachol). Akineton should be administered with caution in conditions which may be associated with significant tachycardia or in patients who show an increased tendency to convulsion. Particular caution is required treating patients with myasthenia gravis. Intraocular pressure should be checked at regular intervals. Caution should also be exercised in cases of existing glaucoma. Impaired memory may arise whilst t Lugege kogu dokumenti