País: Malasia
Idioma: inglés
Fuente: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Tylosin (as tartrate)
Weissen Company (m) Sdn. Bhd.
Tylosin (as tartrate)
Laboratoires BIOVE
PACKAGE INSERT Brand or product name Tylolide Granules for Oral Solution 100 % w/w Name and Strength of Active Substance/ Preservative(s) Composition per tub: Tylosin (as tartrate)…………….100,000,000 IU (Equivalent to 100 g of tylosin per tub or equivalent to 110 g of tylosin tartrate per tub) Product Description Almost white to light yellow granules Pharmacodynamics Tylosin is a macrolide antibiotic produced by a strain of _Streptomyces _ _fradiae._ It exerts its antimicrobial effect by inhibiting protein synthesis of susceptible micro-organisms. The tylosin spectrum of activity includes amongst others Gram- positive bacteria, some Gram – negative strains such as _ Pasteurella_, and _Mycoplasma spp_. Pharmacokinetics In most species peak plasma concentrations have been attained 1 to 2 hours after administration of tylosin. Compared to plasma levels clearly higher tissue concentrations have been observed. Tylosin was extensively metabolised. Environmental Properties Most of the residues are excreted in faeces predominantly consisting of tylosin (factor A), relomycin (factor D) and dihydrodesmycosin. Indication Calves: Treatment and prevention of pneumonia caused by _Mycoplasma spp _when the disease has been established in the herd. Pigs: Treatment and prevention of enzootic pneumonia caused by _Mycoplasma _ _hyopneumoniae_ and _Mycoplasma _ _hyorhinis _ when the disease has been established in the herd. Treatment and prevention of Porcine Intestinal Adenomatosis (Ileitis) associated with _ Lawsonia intracellularis _ when the disease has been established in the herd. Chickens: Treatment and prevention of chronic respiratory diseases (CRD) caused by _Mycoplasma _ _gallisepticum_ and _Mycoplasma _ _synoviae _when the disease has been established in the flock. Treatment and prevention of necrotic enteritis caused by _ Clostridium _ _perfringens_ when the disease has been established in the flock. _ _ Turkeys: Treatment and prevention of infectious sinusitis caused by _Mycoplasma gallisepticum _ when the dis Leer el documento completo