País: Nueva Zelanda
Idioma: inglés
Fuente: Medsafe (Medicines Safety Authority)
Perindopril erbumine 2mg
Clinect NZ Pty Limited
Perindopril erbumine 2 mg
2 mg
Tablet
Active: Perindopril erbumine 2mg Excipient: Lactose Magnesium stearate
Blister pack, aluminium/aluminium, 30 tablets
Prescription
Prescription
Apotex Pharmachem India Pvt. Ltd.
Perindopril is indicated for: · The treatment of hypertension.
Package - Contents - Shelf Life: Blister pack, aluminium/aluminium - 30 tablets - 48 months from date of manufacture stored at or below 25°C protect from light and moisture - Blister pack, aluminium/aluminium - 90 tablets - 48 months from date of manufacture stored at or below 25°C protect from light and moisture
2012-05-16
PERINDOPRIL TABLETS 2mg, 4mg, 8mg 1 New Zealand Consumer Medicine Information PERINDOPRIL _2MG, 4MG, AND 8MG TABLETS _ _Contains the active ingredient perindopril erbumine _ WHAT IS IN THIS LEAFLET This leaflet answers some common questions about PERINDOPRIL. It does not contain all the available information. It does not take the place of talking to your doctor, pharmacist or nurse. If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. All medicines have risks and benefits. Your doctor has weighed the risks of taking PERINDOPRIL against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, ASK YOUR DOCTOR, PHARMACIST OR NURSE. KEEP THIS LEAFLET WITH THE MEDICINE. You may want to read it again. WHAT PERINDOPRIL IS USED FOR PERINDOPRIL is used to treat high blood pressure (also known as hypertension), treatment of heart failure or coronary artery disease. PERINDOPRIL belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors. _HIGH BLOOD PRESSURE _ PERINDOPRIL helps to lower your blood pressure. Everyone has blood pressure. This pressure helps get your blood all around the body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have high blood pressure when your blood pressure stays higher than is needed, even when you are calm or relaxed. There are usually no symptoms of high blood pressure. The only way of knowing that you have it is to have your blood pressure checked on a regular basis. If high blood pressure is not treated it can lead to serious health problems. You may feel fine and have no symptoms, but eventually it can cause stroke, heart disease and kidney failure. _HEART FAILURE _ PERINDOPRIL helps to treat heart failure. Heart failure means that the heart muscle cannot pump blood strongly enough to supply all the blood needed throughout the body. Heart failure is not the same as heart Leer el documento completo
1 NEW ZEALAND DATA SHEET 1. PERINDOPRIL TABLETS PERINDOPRIL 2mg tablet PERINDOPRIL 4mg tablet PERINDOPRIL 8mg tablet 2. QUALITATIVE AND QUANTITATIVE COMPOSITION Each tablet contains: Perindopril erbumine 2mg, 4mg and 8mg _Excipient(s) of known effect _ PERINDOPRIL contains Lactose. PERINDOPRIL is gluten free. For a full list of excipients, see section 6.1. 3. PHARMACEUTICAL FORM PERINDOPRIL 2mg tablets are white, round, biconvex tablets identified by an engraved “APO” on one side and “PE2” on the reverse. PERINDOPRIL 4mg tablets are white, capsule-shaped, biconvex tablets identified by an engraved “APO” on one side and “PE” bisect “4” on the reverse. PERINDOPRIL 8mg tablets are white, capsule-shaped, biconvex tablets identified by an engraved “APO” on one side and “PE” bisect “8” on the reverse. 4. CLINICAL PARTICULARS 4.1 THERAPEUTIC INDICATIONS PERINDOPRIL is indicated for: • the treatment of hypertension; • the treatment of heart failure. In such patients it is recommended that PERINDOPRIL be given with a diuretic and/or digoxin under close medical supervision. (The safety and efficacy of PERINDOPRIL has not been demonstrated for New York Heart Association Category IV patients); • Reduction of risk of cardiovascular events (cardiovascular mortality, myocardial infarction or cardiac arrest) in patients with established coronary artery disease who are stable on concomitant therapy. 2 4.2 DOSE AND METHOD OF ADMINISTRATION DOSE Food intake may reduce hepatic biotransformation of perindopril to perindoprilat. However, whilst this effect has not been shown to be clinically significant, it is recommended that PERINDOPRIL should be taken before meals. RENAL IMPAIRMENT In patients with renal failure, treatment should begin with 2mg daily. Dosage should be adjusted as indicated below according to creatinine clearance. Creatinine and potassium levels should be closely monitored. Creatinine Clearance (mL/min) Dosage Between 30 and 60 2mg daily Between 15 and 30 2mg every 2 days Below Leer el documento completo