FLURISO- isoflurane liquid

País: Estados Unidos

Idioma: inglés

Fuente: NLM (National Library of Medicine)

Ingredientes activos:

Isoflurane (UNII: CYS9AKD70P) (Isoflurane - UNII:CYS9AKD70P)

Disponible desde:

VetOne

Vía de administración:

RESPIRATORY (INHALATION)

tipo de receta:

PRESCRIPTION

indicaciones terapéuticas:

Isoflurane, USP is used for induction and maintenance of general anesthesia in horses and dogs. Isoflurane, USP is contraindicated in horses and dogs with known sensitivity to isoflurane or to other halogenated agents.

Resumen del producto:

Isoflurane, USP is packaged in 250 mL (NDC 13985-945-25) amber-colored bottles.

Estado de Autorización:

Abbreviated New Animal Drug Application

Ficha técnica

FLURISO- ISOFLURANE LIQUID
VETONE
----------
VET one
FLURIS O™
(isoflurane, USP)
LIQUID FOR INHALATION
FOR USE IN HORSES AND DOGS
WARNING:
Not for use in horses intended for food.
CAUTION: Federal law restricts this drug to use by or on the order of
a licensed veterinarian.
DESCRIPTION:
Isoflurane, USP is a nonflammable, nonexplosive general inhalation
anesthetic agent. Its chemical name
is l-chloro-2,2,2- trifluoroethyl difluoromethyl ether, and its
structural formula is:
Each mL contains 99.9% isoflurane.
Some physical constants are:
** Equation for vapor pressure calculation:
Molecular weight
184.5
Boiling point at 760 mm Hg
48.5°C
Refractive index
1.2990-1.30005
Specific gravity 25°/25°C
1.496
Vapor pressure in mm Hg**
20°C
238
25°C
295
30°C
367
35°C
450
Partition coefficients at 37°C
Water/gas
0.61
Blood/gas
1.43
Oil/gas
90.8
Partition coefficients at 25°C - rubber and plastic:
Conductive rubber/gas
62.0
Butyl rubber/gas
75.0
®
Polyvinyl chloride/gas
110.0
Polyethylene/gas
~2.0
Polyurethane/gas
~1.4
Polyolefin/gas
~1.1
Butyl acetate/gas
~2.5
Purity by gas chromatography
>99.9%
Lower limit of flammability
in oxygen or nitrous oxide at 9 joules/sec. and
23˚C
None
Lower limit of flammability in oxygen or nitrous
oxide at 900 joules/sec. and 23˚C
Greater than useful concentration in anesthesia
MAC (Minimum Alveolar Concentration) is 1.31% in horses and 1.28% in
dogs .
Isoflurane is a clear, colorless, stable liquid containing no
additives or chemical stabilizers. Isoflurane
has a mildly pungent, musty, ethereal odor. Samples stored in indirect
sunlight in clear, colorless glass
for five years, as well as samples directly exposed for 30 hours to a
2 amp, 115 volt, 60 cycle long
wave U.V. light were unchanged in composition as determined by gas
chromatography. Isoflurane in
one normal sodium methoxide-methanol solution, a strong base, for over
six months consumed
essentially no alkali, indicative of strong base stability. Isoflurane
does not decompose in the presence
of soda lime (at normal operating