ERYTHROMYCIN BASE FILMTAB tablet coated

País: Estados Unidos

Idioma: inglés

Fuente: NLM (National Library of Medicine)

Ingredientes activos:

ERYTHROMYCIN (UNII: 63937KV33D) (ERYTHROMYCIN - UNII:63937KV33D)

Disponible desde:

Cardinal Health

Designación común internacional (DCI):

ERYTHROMYCIN

Composición:

ERYTHROMYCIN 500 mg

tipo de receta:

PRESCRIPTION DRUG

Estado de Autorización:

Abbreviated New Drug Application

Ficha técnica

ERYTHROMYCIN BASE FILMTAB- ERYTHROMYCIN TABLET, FILM COATED
CARDINAL HEALTH
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ERYTHROMYCIN
BASE FILMTAB®
(ERYTHROMYCIN TABLETS, USP)
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of Erythromycin
Base Filmtab tablets and other antibacterial drugs, Erythromycin Base
Filmtab tablets would be used
only to treat or prevent infections that are proven or strongly
suspected to be caused by bacteria.
DESCRIPTION
Erythromycin Base Filmtab (erythromycin tablets, USP) is an
antibacterial product containing
erythromycin, USP, in a unique, nonenteric film coating for oral
administration. Erythromycin Base
Filmtab tablets are available in two strengths containing either 250
mg or 500 mg of erythromycin base.
Erythromycin is produced by a strain of Saccharopolyspora erythraea
(formerly Streptomyces
erythraeus) and belongs to the macrolide group of antibiotics. It is
basic and readily forms salts with
acids. Erythromycin is a white to off-white powder, slightly soluble
in water, and soluble in alcohol,
chloroform, and ether. Erythromycin is known chemically as (3R*, 4S*,
5S*, 6R*, 7R*, 9R*, 11R*,
12R*, 13S*,
14R*)-4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)
oxy]-14-ethyl-
7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-
6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-
hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione. The molecular
formula is C
H NO , andthe
molecular weight is 733.94. The structural formula is:
INACTIVE INGREDIENTS
Colloidal silicon dioxide, croscarmellose sodium, crospovidone, D&C
Red No. 30 Aluminum Lake,
hydroxypropyl cellulose, hypromellose, hydroxypropyl methylcellulose
phthalate, magnesium stearate,
microcrystalline cellulose, povidone, polyethylene glycol, propylene
glycol, sodium citrate, sodium
hydroxide, sorbic acid, sorbitan monooleate, talc, and titanium
dioxide.
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CLINICAL PHARMACOLOGY
Orally administered erythromycin base and its salts are readily
absorbed in the microbiologically active
form. Interindividual variations in the abso