País: Singapur
Idioma: inglés
Fuente: HSA (Health Sciences Authority)
Cefotaxime Sodium equivalent to Cefotaxime
PHARMAKOE PTE. LTD.
J01DD01
INJECTION, POWDER, FOR SOLUTION
Cefotaxime Sodium equivalent to Cefotaxime 0.5g/vial
INTRAVENOUS, INTRAMUSCULAR
Prescription Only
TENAMYD PHARMACEUTICAL CORPORATION
ACTIVE
2021-11-10
PRODUCT INFORMATION Company logo CYTAXIN CEFOTAXIME POWDER FOR SOLUTION FOR INJECTION 0.5G & 1G COMPOSITION: CYTAXIN 0.5G: Each vial of dry powder contains 524mg cefotaxime sodium, corresponding to 500mg cefotaxime. CYTAXIN 1G: Each vial of dry powder contains 1048mg cefotaxime sodium, corresponding to 1000mg cefotaxime. DESCRIPTION: CYTAXIN 0.5G: Off-white to pale yellow crystalline powder. After reconstitution, the solution should be pale yellow to light amber colour. CYTAXIN 1G: Off-white to pale yellow crystalline powder. After reconstitution, the solution should be pale yellow to light amber colour. PROPERTIES Cytaxin is an antibiotic of the cephalosporin group and has a bactericidal effect. Its antibiotic activity against Gram-negative rod-shaped bacteria is many times stronger than that of the traditional cephalosporin and penicillins. In most pathogens, its minimum bactericidal concentration is slightly higher than its minimum inhibitory concentration. Resistance develops slowly, as with penicillin. In vitro studies of combinations of Cefotaxime with aminoglycoside antibiotics reveal a synergistic or additive effect. The serum protein binding is 32 – 50%, depending on the method used, After injection, high Cefotaxime concentrations clearly exceeding the susceptibility of most pathogens are obtained in serum, tissues, and body fluids. Cefotaxime is excreted mainly through the kidneys in an antibacterially active form. INDICATIONS Severe infections caused by cefotaxime-susceptible pathogens; Infections - of the respiratory tract, including nose and throat - of the ear - of the kidneys and urinary tract, - of the skin and soft tissues - of the bones and joints, - of the genital organs including gonorrhoea, - of the abdominal region Sepsis, endocartitis, meningitis: for perioperative prophylaxis in patients who are at increased risk from infection, and for the prophylaxis of infections in patients with reduced resistance. Cefotaxime is generally effective against the following pathogens: Staphylococci, aero Leer el documento completo