País: Australia
Idioma: inglés
Fuente: Department of Health (Therapeutic Goods Administration)
cyproterone acetate
Alphapharm Pty Ltd
Medicine Registered
CYPRONE 1 CYPRONE _Cyproterone acetate_ CONSUMER PRODUCT INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about this medicine. It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking Cyprone against the benefits they expect it will have for you. IF YOU HAVE ANY CONCERNS ABOUT TAKING THIS MEDICINE, TALK TO YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH YOUR MEDICINE. You may need to read it again. WHAT CYPRONE IS USED FOR Cyprone is used for a number of conditions, as follows:- * in the treatment of women who have a problem with facial or chest hair, are balding, or have severe acne * in the treatment of men with cancer of the prostate gland * to reduce the sex drive of men with sexual deviations ASK YOUR DOCTOR IF YOU HAVE ANY QUESTIONS ABOUT WHY CYPRONE HAS BEEN PRESCRIBED FOR YOU. Your doctor may have prescribed Cyprone for another purpose. Cyprone is a hormone preparation that works by reducing the effects and the levels of male sex hormones in the body. [These male sex hormones are also produced by women in small amounts, and if the body produces too much or is overly sensitive, then masculine features can occur in women]. Cyprone is available only with a doctor's prescription. There is no evidence that Cyprone is addictive. BEFORE YOU TAKE CYPRONE Female patients should be aware that the long-term effects of Cyprone on fertility are not known. Male patients should be aware that Cyprone causes a decrease in sperm count. It may take 3 to 20 months for the sperm count to return to normal once therapy has been stopped. Patients should be aware that there have been reports of liver damage including liver failure, tumours and bleeding into the liver in patients receiving high doses of cyproterone acetate. Consu Leer el documento completo
CYPRONE YPRONE _Cyproterone Acetate _ _Cyproterone Acetate _ PRODUCT INFORMATION PRODUCT INFORMATION NAME OF THE MEDICINE The active ingredient of Cyprone tablets is cyproterone acetate. The chemical name for cyproterone acetate is 6-chloro-17-hydroxy-1 α,2α-methylenepregna-4,6-diene-3,20- dione acetate. Its structural formula is: O Cl Me H Me OAc H 2 C H H O CH 3 Molecular formula: C 24 H 29 ClO 4 Molecular weight: 416.94 CAS Registry No.: 427-51-0 DESCRIPTION Cyproterone acetate is a white to pale yellow, odourless crystalline powder. It is practically insoluble in water. Each Cyprone tablet contains 50 mg of cyproterone acetate. The tablets also contain the following inactive excipients: lactose, maize starch, povidone, colloidal anhydrous silica and magnesium stearate. _The tablets are gluten free._ PHARMACOLOGY Cyproterone acetate is a synthetic antiandrogenic hormone preparation. It is believed to prevent the effect of endogenously produced and exogenously administered androgens at the target organs by means of competitive inhibition. The stimulating effect of male sex hormones on androgen dependent structures and functions is weakened or counteracted by cyproterone acetate. Cyproterone acetate also exerts a progestational and antigonadotrophic effect. Treatment with cyproterone acetate in men results in a reduction of sexual drive and potency and inhibition of gonadal function. These changes are reversible following discontinuation of therapy. The function of androgen dependent target organs, such as the prostate, is restricted. Prostatic carcinoma and its metastases are in general androgen dependent. Cyproterone acetate exerts a direct antiandrogenic action on the tumour and its metastases, and in addition it exerts a negative feedback effect on the hypothalamic receptors, thereby leading to a reduction in gonadotrophin release, and hence to di Leer el documento completo