CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE capsule

País: Estados Unidos

Idioma: inglés

Fuente: NLM (National Library of Medicine)

Ingredientes activos:

chlordiazepoxide hydrochloride (UNII: MFM6K1XWDK) (chlordiazepoxide - UNII:6RZ6XEZ3CR)

Disponible desde:

Oceanside Pharmaceuticals

Designación común internacional (DCI):

chlordiazepoxide hydrochloride

Composición:

chlordiazepoxide hydrochloride 5 mg

tipo de receta:

PRESCRIPTION DRUG

Estado de Autorización:

New Drug Application Authorized Generic

Ficha técnica

CHLORDIAZEPOXIDE HYDROCHLORIDE AND CLIDINIUM BROMIDE- CHLORDIAZEPOXIDE
HYDROCHLORIDE AND CLIDINIUM BROMIDE CAPSULE
OCEANSIDE PHARMACEUTICALS
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CHLORDIAZEPOXIDE HCL/
CLIDINIUM BROMIDE
CAPSULES
_to control emotional_
_and somatic factors_
_in gastrointestinal disorders_
DESCRIPTION
Chlordiazepoxide HCl/Clidinium Bromide combines in a single capsule
formulation the antianxiety
action of chlordiazepoxide hydrochloride and the
anticholinergic/spasmolytic effects of clidinium
bromide, both exclusive developments of Roche research.
Each Chlordiazepoxide HCl/Clidinium Bromide capsule contains 5 mg
chlordiazepoxide hydrochloride
and 2.5 mg clidinium bromide. Each capsule also contains corn starch,
lactose and talc. Gelatin capsule
shells may contain methyl and propyl parabens and potassium sorbate,
with the following dye systems:
D&C Yellow No. 10 and either FD&C Blue No. 1 or FD&C Green No. 3.
Chlordiazepoxide hydrochloride is a versatile, therapeutic agent of
proven value for the relief of
anxiety and tension. It is indicated when anxiety, tension or
apprehension are significant components of
the clinical profile. It is among the safer of the effective
psychopharmacologic compounds.
Chlordiazepoxide hydrochloride is
7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepine 4-oxide
hydrochloride. A colorless, crystalline substance, it is soluble in
water. It is unstable in solution and the
powder must be protected from light. The molecular weight is 336.22.
The structural formula of
chlordiazepoxide hydrochloride is as follows:
Clidinium bromide is a synthetic anticholinergic agent which has been
shown in experimental and
clinical studies to have a pronounced antispasmodic and antisecretory
effect on the gastrointestinal tract.
Structurally clidinium bromide is:
ANIMAL PHARMACOLOGY
Chlordiazepoxide hydrochloride has been studied extensively in many
species of animals and these
studies are suggestive of action on the limbic system of the brain,
which recent evidence indicates is
involved in emotional responses.
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