AVELAC ORAL SOLUTION 667mgml

País: Malasia

Idioma: inglés

Fuente: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ingredientes activos:

Lactulose

Disponible desde:

APEX PHARMACY MARKETING SDN. BHD.

Designación común internacional (DCI):

Lactulose

Unidades en paquete:

100 ml; 200 ml

Fabricado por:

XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD

Información para el usuario

_Consumer Medication Information Leaflet (RiMUP) _
_ _
_ _
_ _
___________________________________________________________________________________________________________________________
_
1
WHAT IS IN THIS LEAFLET:
1.
What is AVELAC used for
2.
How AVELAC works
3.
Before you use AVELAC
4.
How to use AVELAC
5.
While you are using AVELAC
6.
Side effects
7.
Storage and disposal of AVELAC
8.
Product description
9.
Manufacturer and Product Registration
Holder
10.
Date of revision
_ _
WHAT IS AVELAC USED FOR
It helps in softening the stools and relieves
constipation.
Hepatic
encephalopathy
(HE):
treatment
and
prevention
of
hepatic
coma
or
precoma.
HOW AVELAC WORKS
AVELAC
contains
lactulose,
a
laxative
that
producing
bowel
movement
and
softening the stools.
BEFORE YOU USE AVELAC
_When you must not use it _
Do not use AVELAC if:

You
have
galactosaemia
(genetic
disease
where
galactose
cannot
be
metabolized properly)

You are on a galactose diet.

You are lactose intolerance

You are a diabetic patients because of
the presence of some free simple sugar.

You
are
having
an
intestinal
obstruction.
_ _
_Before you start to use it _
Tell your doctor or pharmacist before using
AVELAC if:

You are pregnant or breast-feeding.

You
are
taking
other
medications
including herbs and supplements.
_ _
_Taking other medicines _
Tell your doctor or pharmacist if you are
taking or have recently taken any other
medicines. This includes any medicines
which you have bought without a
prescription.
_ _
HOW TO USE AVELAC
_How much to use_
_CONSTIPATION _
It may take up to 48 hours before an effect
is obtained. The dose is gradually adjusted
according to response.
_ _
_ _
AGE
GROUP
STARTING
DOSE
MAINTENANCE
DOSE
Adults
15ml – 45ml
15ml – 30ml
Children
(7 - 14
years old)
15ml
10ml – 15ml
Children
(1 - 6
years old)
5ml – 10ml
5ml – 10ml
Infant
(less than
1 year)
5ml
5ml
_HEPATIC ENCEPHALOPATHY _
For Adults only.
30ml - 45ml, 3 to 4 times daily. The dose is
subsequently adjusted to produce 2 - 3 soft
stools daily.
_

Ficha técnica

Important Information. Please read carefully.
AVELAC
ORAL SOLUTION
(LACTULOSE 667 MG/ML)
WHAT IS AVELAC?
Description, Dosage form and Packaging
AVELAC is a clear, viscous liquid, colorless to brownish yellow
aqueous solution.
This product is available in pack size of 100ml and 200ml.
WHAT IS AVELAC USED FOR?
AVELAC helps in softening the stools and relieves constipation.
Hepatic encephalopathy (HE): treatment and prevention of hepatic coma
or precoma.
HOW AVELAC WORKS?
AVELAC contains lactulose, a laxative that producing bowel movement
and softening the stools.
Pharmacodynamics
Lactulose is a synthetic disaccharide osmotic laxative used in the
treatment of constipation and in hepatic encephalopathy. Lactulose
is broken down by colonic bacteria mainly into lactic acid. This
exerts a local osmotic effect in the colon resulting in increased
faecal bulk and stimulation of peristalsis. It may take up to 48 hours
before an effect is obtained. When larger doses are given for
hepatic encephalopathy, the pH in the colon is reduced significantly
and the absorption of ammonium ions ad other toxic nitrogenous
compounds is decreased, leading to a fall in blood-ammonia
concentration and an improvement in mental function.
Pharmacokinetics
Taken orally, lactulose passes essentially unchanged into the large
intestine where it is metabolized by saccharolytic bacteria with
the formation of simple organic acids, mainly lactic acid and small
amounts of acetic and formic acids. The small amount of absorbed
lactulose is subsequently excreted unchanged in the urine.
HOW TO USE AVELAC?
AVELAC is for oral consumption only. Shake well before use.
_ _
_CONSTIPATION _
It may take up to 48 hours before an effect is obtained. The dose is
gradually adjusted according to response.
_ _
AGE GROUP
STARTING DOSE
MAINTENANCE DOSE
Adults
15ml – 45ml
15ml – 30ml
Children (7 - 14 years old)
15ml
10ml – 15ml
Children (1 - 6 years old)
5ml – 10ml
5ml – 10ml
Infant (less than 1 year)
5ml
5ml
_HEPATIC ENCEPHALOPATHY _
For Adults only.
30ml - 45ml,