País: Estados Unidos
Idioma: inglés
Fuente: NLM (National Library of Medicine)
IVERMECTIN (UNII: 8883YP2R6D) (IVERMECTIN - UNII:8883YP2R6D)
Agri Laboratories, Ltd.
IVERMECTIN
IVERMECTIN 10 mg in 1 mL
SUBCUTANEOUS
OTC
AGRI-MECTIN Injection has been proved to effectively control infections and to protect cattle from reinfection with Dictyocaulus viviparus and Oesophagostomum radiatum for 28 days after treatment; Ostertagia ostertagi, Trichostrongylus axei and Cooperia punctata for 21 days after treatment; Haemonchus placei and Cooperia oncophora for 14 days after treatment. Swine : AGRI-MECTIN Injection is indicated for the effective treatment and control of the following harmful species of gastrointestinal roundworms, lungworms, lice and mange mites in swine:
50 mL, 200 mL, 500 mL
Abbreviated New Animal Drug Application
AGRI-MECTIN - IVERMECTIN INJECTION AGRI LABORATORIES, LTD. ---------- AGRI-MECTIN (IVERMECTIN) ANADA 200-429, Approved by FDA INJECTION FOR CATTLE AND SWINE 1% STERILE SOLUTION A PARASITICIDE FOR THE TREATMENT AND CONTROL OF INTERNAL AND EXTERNAL PARASITES OF CATTLE AND SWINE CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT, AND CONTROL OF PARASITISM. INTRODUCTION AGRI-MECTIN is an injectable parasiticide for cattle and swine. One low-volume dose effectively treats and controls the following internal and external parasites that may impair the health of cattle and swine: gastrointestinal roundworms (including inhibited _Ostertagia ostertagi_ in cattle), lungworms, grubs, sucking lice, and mange mites of cattle; and gastrointestinal roundworms, lungworms, lice, and mange mites in swine. PRODUCT DESCRIPTION Ivermectin is derived from the avermectins, a family of potent, broad-spectrum antiparasitic agents isolated from fermentation of_ Streptomyces avermitilis._ AGRI-MECTIN Injection is a clear, ready-to-use, sterile solution containing 1% ivermectin, 40% glycerol formal, and propylene glycol, q.s. ad 100%. AGRI-MECTIN Injection is formulated to deliver the recommended dose level of 200 mcg ivermectin/kilogram of body weight in cattle when given subcutaneously at the rate of 1 mL/110 lb (50 kg). In Swine, AGRI-MECTIN Injection is formulated to deliver the recommended dose level of 300 mcg ivermectin/kilogram body weight when given subcutaneously in the neck at the rate of 1 mL/75 lbs (33 kg). MODE OF ACTION Ivermectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells. This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with o Leer el documento completo