VYALEV combination subcutaneous infusion (ヴィアレブ配合持続皮下注)

Country: Japan

Language: English

Source: すりの適正使用協議会 RAD-AR Council, Japan

Active ingredient:

Foslevodopa; Foscarbidopa hydrate

Available from:

AbbVie GK

INN (International Name):

Foslevodopa; Foscarbidopa hydrate

Pharmaceutical form:

Colorless to yellow or brown limpid injection. It may have a reddish or purplish tinge or a slight opalescent light.

Patient Information leaflet

Drug Information Sheet("Kusuri-no-Shiori")
Self-injection
Published: 05/2023
The information on this sheet is based on approvals granted by the
Japanese regulatory authority. Approval
details may vary by country. Medicines have adverse reactions (risks)
as well as efficacies (benefits). It is
important to minimize adverse reactions and maximize efficacy. To
obtain a better therapeutic response,
patients should understand their medication and cooperate with the
treatment.
BRAND NAME:
VYALEV COMBINATION SUBCUTANEOUS INFUSION
ACTIVE INGREDIENT:
Foslevodopa
Foscarbidopa hydrate
DOSAGE FORM:
Colorless to yellow or brown limpid injection. It may have a
reddish or purplish tinge or a slight opalescent light.
IMPRINT OR PRINT ON WRAPPING:
EFFECTS OF THIS MEDICINE
This medicine is converted in the body from foslevodopa and
foscarbidopa to levodopa and
carbidopa, respectively. Levodopa is taken up in the brain and acts as
dopamine, while
carbidopa facilitates the transfer of levodopa into the brain, and
this combination improves
daily variations in the symptoms of Parkinson's disease.
It is usually used to improve daily variations in the symptoms of
Parkinson's disease (wearing-
off phenomenon) when existing pharmacotherapy, including
levodopa-containing medications,
has not been sufficiently effective.
THE FOLLOWING PATIENTS MAY NEED TO BE CAREFUL WHEN USING THIS
MEDICINE.BE SURE TO TELL YOUR DOCTOR
AND PHARMACIST.
・If you have previously experienced any allergic reactions (itching,
rash, etc.) to any
medicines or foods.
If you have angle-closure glaucoma, lung disease, bronchial asthma or
endocrine system
diseases, chronic open angle glaucoma, diabetes mellitus, renal
dysfunction, or hepatic
dysfunction.
If you have or have a history of gastric ulcer, duodenal ulcer,
cardiac disease, or
psychological symptoms (e.g., suicidal tendency).
・If you are pregnant or breastfeeding.
・If you are taking any other medicinal products. (Some medicines may
interact to enhance or
diminish medicinal effects. Beware of over-the-coun