Vancocin CP

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Vancomycin

Available from:

Aspen Pharmacare Australia Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

VANCOCIN CP CMI - 230310 

Page 1 of 3 

WHAT IS IN THIS LEAFLET

This leaflet answers some common 
questions about Vancocin CP powder 
for injection.  It does not contain all the 
available information and does not take 
the place of talking to your doctor. 

All medicines have risks and benefits. 
Your doctor has weighed the risks of 
you taking this medicine against the 
benefits they expect it will have for you. 

IF YOU HAVE ANY CONCERNS ABOUT BEING 
GIVEN THIS MEDICINE, TALK TO YOUR 
DOCTOR OR PHARMACIST. 

KEEP THIS LEAFLET WITH THIS MEDICINE.   

You may need to read it again. 

WHAT VANCOCIN CP IS USED 
FOR

Vancocin CP contains the active 
vancomycin (as vancomycin 
hydrochloride).  

Vancocin CP is an antibiotic used to 
treat serious infections caused by 
bacteria (germs).  These infections may 
occur in different parts of the body. 

Vancocin CP can also be used orally to 
treat serious infections involving the 
bowel. 

Vancocin CP works by killing the 
bacteria causing the infection. 

ASK YOUR DOCTOR IF YOU HAVE ANY 
QUESTIONS ABOUT WHY VANCOCIN CP 
HAS BEEN PRESCRIBED FOR YOU.  

Your doctor may have prescribed 
Vancocin CP for another reason.   

This medicine is only available with a 
doctor’s prescription. 

There is no evidence that it is addictive. 
BEFORE YOU ARE GIVEN IT

_WHEN YOU MUST NOT BE GIVEN IT _

YOU SHOULD NOT BE GIVEN VANCOCIN 
CP IF YOU HAVE EVER HAD AN ALLERGIC 
REACTION TO: 

•  any medicines containing 
vancomycin hydrochloride 
•  the inactive ingredient, disodium 
edetate.   

Signs of an allergic reaction may 
include shortness of breath, wheezing 
or difficulty in breathing; swelling of 
the face, lips, tongue or any other parts 
of the body; rash, itching or hives on 
the�

Summary of Product characteristics

 
PRODUCT INFORMATION 
VIALS 

VANCOCIN CP 
(Sterile Vancomycin Hydrochloride) 
Intravenous 

NAME OF THE MEDICINE 

VANCOCIN CP (vancomycin hydrochloride) has the chemical formula 
C
66
H
75
Cl
2
N
9
O
24
.HCl.  

The formula weight is 1449; 500 mg of the base is equivalent to 0.35
mmol. The 
CAS number is 1404-93-9. 

The following structure of vancomycin hydrochloride has been confirmed
by X-ray 
diffraction: 

[http://www.pharmacopoeia.co.uk/bp2009/ixbin/bp.cgi?a=imagezoom&file=bp2009_v2_08_01_monographs_medicinal_and_pharmaceutical_substances/large/vancomycinhydrochloride_1_2009_60_cs.png]

DESCRIPTION 

Vancocin CP (Sterile Vancomycin Hydrochloride), Intravenous, is a 
chromatographically purified tricyclic glycopeptide antibiotic
derived from 
_Amycolatopsis orientalis _(formerly _Nocardia orientalis_) which is
bactericidal against 
many gram-positive bacteria. It should be administered intravenously
in dilute 
solution (_see_ DOSAGE AND ADMINISTRATION).  
VANCOCIN CP powder for injection vial - Product Information 
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VANCOCIN CP powder for injection vial - Product Information 
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Vancocin CP is available as sterile vials containing vancomycin
equivalent to either  
500 mg (500,000 IU) or 1 g (1,000,000 IU) of vancomycin activity.  It
is an off-white 
lyophilised plug.  When reconstituted in water, it is a clear
solution with a pH range of 
2.8 to 4.5.  Disodium edetate has been added during processing.
Sodium hydroxide 
and/or hydrochloric acid may be used during manufacture for pH
adjustment. 

CLINICAL PHARMACOLOGY 

Vancocin CP is poorly absorbed after oral administration; it is given
intravenously for 
therapy of systemic infections.  Intramuscular injection is
painful. 

In subjects with normal kidney function, multiple intravenous dosing
of  
1 g of vancomycin (15 mg/kg) infused over 60 minutes produces mean
plasma 
concentrations of approximatel