Terry White Chemists Cefaclor Suspension

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Cefaclor monohydrate

Available from:

Apotex Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

TERRY WHITE CHEMISTS
CEFACLOR ORAL
SUSPENSION

_Contains the active ingredient, Cefaclor (as cefaclor monohydrate)_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
READ THIS LEAFLET CAREFULLY BEFORE
TAKING YOUR MEDICINE.
THIS LEAFLET ANSWERS SOME COMMON
QUESTIONS ABOUT CEFACLOR.
It does not contain all the available
information.
It does not take the place of talking to
your doctor or pharmacist.
The information in this leaflet was
last updated on the date listed on the
last page. More recent information on
this medicine may be available.
ASK YOUR DOCTOR OR PHARMACIST:
•
if there is anything you do not
understand in this leaflet,
•
if you are worried about taking
your medicine, or
•
to obtain the most up-to-date
information.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using this medicine
against the benefits they expect it
will have for you.
Pharmaceutical companies cannot
give you medical advice or an
individual diagnosis.
Keep this leaflet with your medicine.
You may want to read it again.
WHAT THIS MEDICINE IS
USED FOR
The name of your medicine is Terry
White Chemists Cefaclor. It contains
the active ingredient, cefaclor (as
cefaclor monohydrate).
It is used to treat infections caused by
bacteria in different parts of the body
such as:
•
chest and lungs (lower respiratory
tract)
•
ears, nose, throat and tonsils
(upper respiratory tract)
•
bladder and kidneys (urinary
tract)
•
skin
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you.
Your doctor may have prescribed it
for another reason.
This medicine is available only with
a doctor's prescription.
_HOW IT WORKS_
Cefaclor is an antibiotic which
belongs to a group called
cephalosporins. These are closely
related to penicillins.
It works by killing the bacteria
causing your infection or by stopping
its growth.
It will not work against infections
caused by viruses such as colds or
the flu.
There is no evidence that this
medicine is addictive.
This medici

Summary of Product characteristics

Product Information – Australia 
Terry White Chemists Cefaclor Suspension 
Page 1 
TERRY WHITE CHEMISTS CEFACLOR SUSPENSION  

NAME OF THE MEDICINE 
Cefaclor monohydrate 

Chemical name:  
3-chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid 
monohydrate. 

Structural formula: 

Molecular formula:   
C
15
H
14
CIN
3
O
4
S.H
2
O.   

Molecular Weight: 
385.8 

CAS Registry number:   70356-03-5.   

DESCRIPTION 
Cefaclor monohydrate is a white to off-white crystalline
powder, slightly soluble in water, but is insoluble in 
alcohol and chloroform.   

PHARMACOLOGY 
Cefaclor is a semisynthetic, broad spectrum cephalosporin
antibiotic for oral administration. 

PHARMACOKINETICS 
Cefaclor is well absorbed after oral administration, whether taken with food or while fasting.  However, 
when it is taken with food, the peak concentration achieved
is 50 to 75% of that observed when the drug 
is administered to fasting subjects and generally appears from 45 to 60 minutes later.  The presence of 
food in the gastrointestinal tract does not alter the
total amount of cefaclor absorbed.  Following 
administration of 250 mg, 500 mg and 1 g doses to fasting
subjects, average peak plasma levels of 
antibacterial activity (expressed as µg/mL
of cefaclor) of 7, 13 and 23 µg/mL, respectively, were
obtained 
at 30 to 60 minutes.  The reduced peak serum levels resulting from the administration of cefaclor with 
food should be considered with reference to the sensitivity of the infecting organism, severity of illness, 
the dose being administered and the variability in the peak plasma
levels which occur with cefaclor. 

The plasma half-life in
healthy subjects is independent of dosage form and averages 40
to 60 minutes.  In 
elderly subjects (>65 years) with normal serum