Country: Canada
Language: English
Source: Health Canada
DIETHYLPROPION HYDROCHLORIDE
SANOFI-AVENTIS CANADA INC
A08AA03
AMFEPRAMONE
25MG
TABLET
DIETHYLPROPION HYDROCHLORIDE 25MG
ORAL
100
Schedule G (CDSA IV)
Amphetamine Derivatives
Active ingredient group (AIG) number: 0102499002; AHFS:
CANCELLED POST MARKET
2009-03-24
PRODUCT MONOGRAPH TENUATE ® (diethylpropion hydrochloride) Tablets, 25 mg TENUATE ® DOSPAN ® (diethylpropion hydrochloride) Continuous Release Tablets, 75 mg Anorexiant sanofi-aventis Canada Inc. Date of Preparation: 2150 St. Elzear Blvd. West March 23, 2006 Laval, Quebec H7L 4A8 Submission Control No. 104730 s-a Version 1.0 dated 1 PRODUCT MONOGRAPH TENUATE ® (diethylpropion hydrochloride) Tablets, 25 mg TENUATE ® DOSPAN ® (diethylpropion hydrochloride) Continuous Release Tablets, 75 mg THERAPEUTIC CLASSIFICATION Anorexiant ACTION TENUATE ® (diethylpropion hydrochloride) is a psychomotor stimulant with anorectic, sympathomimetic and other effects similar to those of amphetamines. As with all other drugs of this class in which the phenomenon has been studied, the initial rate of weight loss decreases until a plateau is reached; a regain of weight thereafter even though drug administration is continued has been reported. As with similar drugs, rebound weight gain also may occur after discontinuation of TENUATE ® . INDICATIONS AND CLINICAL USE A psychomotor stimulant used as an adjunct in the short-term (i.e. a few weeks) to continued dietary treatment in the medical management of obesity, in patients who have not responded to an appropriate weight reducing regimen (diet and/or exercise) alone. TENUATE ® is recommended only for obese patients with an initial body mass index $ 30 kg/m 2 , or $ 27 kg/m 2 in the presence of other risk factors (e.g. hypertension, diabetes, hyperlipidaemia). Below is a chart of Body Mass Index (BMI) based on various heights and weights. BMI is calculated by taking the patient’s weight, in kilograms, divided by the patient’s height in meters and squared. Metric conversions are as follows: 2 S Pounds(lbs)/2.2 = kilograms (kg) S Feet (ft) x 0.3048 = meters (m) S Inches x 0.0254 = meters (m) BODY MASS INDEX (BMI), kg/m 2 Height (feet, inches) Weight (pounds) 5'0" 5'3" 5'6" 5'9" 6'0" 6'3" 140 27 25 23 21 19 18 150 29 27 24 22 20 19 160 31 28 26 24 22 20 170 33 30 28 25 23 21 180 Read the complete document