Sulphur Colecton (Cattle)

Country: United Kingdom

Language: English

Source: VMD (Veterinary Medicines Directorate)

Active ingredient:

Salicylic Acid, Sulphur

Available from:

Mr J J & Mrs M A Zakarias

INN (International Name):

Salicylic Acid, Sulphur

Authorization status:

Expired

Summary of Product characteristics

PART 1 B:
SUMMARY OF PRODUCT CHARACTERISTICS - (SPC)
1. NAME OF THE VETERINARY MEDICINAL PRODUCT
Sulphur Colecton (Cattle)
2. QUALITATIVE AND QUANTITATIVE COMPOSITION
A.1 Quantitative Composition Of The Proprietary Product
A1.1 Active Constituents
Constituent
Quantity
Sulphur for external use. 10.0% (w/w)
Salicylic Acid.
1.5% (w/w
in an aqueous gel base.
3. PHARMACEUTICAL FORM
Gel:
Yellow aqueous gel for topical application in cattle.
4. PHARMACOLOGICAL PROPERTIES
SUMMARY PRESENTATION OF THE ACTIVE INGREDIENTS
Salicylic acid is an aromatic carboxylic acid possessing
anti-inflammatory,
analgesic, antimicrobial and keratolytic properties. Anti-inflammatory
and analgesic
action appears to be mediated by the inhibition of prostaglandin
synthesis via the
inhibition of the cylo-oxygenase enzyme.
Sulphur is a non-metallic element, used for
topical dermatologic
therapy,
possessing
antiseptic,
antifungal,
antiparasitic,
anti-acne,
anti-pruritic,
antiseborrhoeic and keratolytic properties. Pharmacological action is
mediated
through the formation of disulphides and polythionic acids formed by
the
interaction of sulphur with organic substances or micro-organisms
present on the
skin.
4.1 PHARMACODYNAMIC PROPERTIES
Salicylic acid:
Exhibits antimycotic and antimicrobial actions and is considered a
safe broad
spectrum antiseptic. In addition salicylic acid has anti-inflammatory
and analgesic
properties. Salicylic acid also has keratolytic properties with
keratin dispersing
and keratostatic activities. Salicylic acid displays superficial
astringent and anti-
pruritic properties.
Salicylic acid appears to exert its anti-inflammatory action and
analgesic properties
by the inhibition of prostaglandin synthesis via the inhibition of the
cylo-oxygenase
enzyme.
Salicylic acid belongs to the group of aromatic carboxylic acids and
is also
considered a member of the group of non-steroidal anti-inflammatory
substances
(NSAIDS).
1
Sulphur for External Use
Sulphur exhibits antiseptic, antifungal and antiparasitic properties.
Additionally
ant