Sodium Bicarbonate

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Sodium bicarbonate

Available from:

Phebra Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

SODIUM
BICARBONATE

_INTRAVENOUS INFUSION_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Sodium Bicarbonate
Intravenous Infusion. It does not
contain all the available information.
It does not take the place of talking to
your doctor or pharmacist.
All medicines have benefits and
risks. Your doctor has weighed the
risks of you being given Sodium
Bicarbonate Intravenous Infusion
against the benefits they expect it to
have for you.
This medicine is likely to be used
while you are at the clinic or in
hospital. If possible, please read this
leaflet carefully before this medicine
is given to you. In some cases this
leaflet may be given to you after the
medicine has been used.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET.
You may need to read it again.
WHAT SODIUM
BICARBONATE
INTRAVENOUS
INFUSION IS USED FOR
Sodium Bicarbonate Intravenous
Infusion is given to patients who
have too much acid, or who have not
enough sodium or bicarbonate in
their blood. This chemical is
naturally present in body fluids and is
needed for normal body function.
Sodium Bicarbonate Intravenous
Infusion may be used for the
treatment of other conditions that are
not mentioned above. Your doctor
will be able to tell you about the
specific condition for which you
have been given Sodium Bicarbonate
Intravenous Infusion.
Ask your doctor if you have any
questions about why it has been
given to you.
BEFORE YOU ARE TREATED
WITH SODIUM
BICARBONATE
INTRAVENOUS
INFUSION
_WHEN YOU MUST NOT TAKE IT_
YOU SHOULD NOT BE GIVEN SODIUM
BICARBONATE INTRAVENOUS INFUSION
IF YOU HAVE AN ALLERGY TO:
•
any medicine containing sodium
bicarbonate
•
any of the ingredients listed at the
end of this leaflet.
Some of the symptoms of an allergic
reaction may include:
•
shortness of breath
•
wheezing or difficulty breathing
•
swelling of the face, lips, tongue
or other parts of the body
•
rash, itching or hives on the skin.
SODIUM BICARB

Summary of Product characteristics

Version:  pfpsodbi11112 
Supersedes: pfpsodbi10610 

Page 1 of 7 
PRODUCT INFORMATION 
SODIUM BICARBONATE INTRAVENOUS INFUSION BP 8.4% 
(SODIUM BICARBONATE)  
NAME OF THE MEDICINE  
Sodium bicarbonate  

Molecular Formula: 
NaHCO
3 
CAS Number:  144-55-8 
DESCRIPTION  
DESCRIPTION 
A  sterile,  hypertonic,  preservative-free  solution  containing  Sodium  Bicarbonate  84  mg/mL 
and Disodium Edetate in Water for Injections.  Each mL of solution contains 1mmol each of 
sodium and bicarbonate ions. 

PHARMACOLOGY 
PHARMACODYNAMICS 
Sodium  bicarbonate  is  a  systemic  alkalising  agent  which,  when  given  intravenously  will 
increase plasma bicarbonate, buffers excess hydrogen ion concentration, raises blood pH and 
reverses the clinical manifestations of acidosis. 
PHARMACOKINETICS 
Sodium  bicarbonate  dissociates  in  water  to  provide  sodium  (Na
+
)  and  bicarbonate  (HCO
-
3
) 
ions.    Sodium  is  the  principal  cation  of  the  extracellular  fluid.    Bicarbonate  is  a  normal 
constituent of body fluids and the normal plasma level ranges from 24 to 31 mmol/L.  Plasma 
concentration is regulated by the kidney.  The bicarbonate anion, at the correct concentration 
of  hydrogen  ion  (H
+
)  may  be  converted  to  carbonic  acid  (H
2
CO
3
),  then  to  its  volatile  form, 
carbon dioxide (CO
2
) which is excreted by the lung.  Normally, a ratio of 1:20 (carbonic acid: 
bicarbonate) is present in the extracellular fluid.   
_EXCRETION _
In  a  healthy  adult  with  normal  kidney  function,  practically  all  the  glomerular  filtered 
bicarbonate ion is reabsorbed and less than 1 % is excreted in the
urine. 
Version:  pfpsodbi11112 
Supersedes: pfpsodbi10610 

Page 2 of 7 
INDICATIONS 
METABOLIC