SENTINEL SPECTRUM 2-8LBS- milbemycin oxime, lufenuron, praziquantel tablet, chewable

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

MILBEMYCIN OXIME (UNII: 0502PUN0GT) (MILBEMYCIN OXIME - UNII:0502PUN0GT), LUFENURON (UNII: 1R754M4918) (LUFENURON - UNII:1R754M4918), PRAZIQUANTEL (UNII: 6490C9U457) (PRAZIQUANTEL - UNII:6490C9U457)

Available from:

Virbac AH, Inc

INN (International Name):

MILBEMYCIN OXIME

Composition:

MILBEMYCIN OXIME 2.3 mg

Administration route:

ORAL

Prescription type:

PRESCRIPTION

Therapeutic indications:

SENTINEL SPECTRUM is indicated for the prevention of heartworm disease caused by Dirofilaria immitis ;for the prevention and control of flea populations (Ctenocephalides felis ); and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina ), adult hookworm (Ancylostoma canium ), adult whipworm (Trichuris vulpis ), and adult tapeworm (Taenia pisiformis, Echinococcus multilocularis and Echinococcus granulosus ) infections in dogs and puppies, two pounds of body weight or greater and six weeks of age and older. There are no known contraindications to the use of SENTINEL SPECTRUM.

Product summary:

SENTINEL SPECTRUM is available in four strengths formulated according to the weight of the dog. Each strength is available in color-coded packages of six or twelve chewable tablets each. Manufactured for: Virbac AH, Inc. P.O. Box 162059, Ft Worth, TX 76161 NADA #141-333, Approved by FDA © 2015 Virbac Corporation. All Rights Reserved. SENTINEL and SPECTRUM are registered trademarks of Virbac Corporation.

Authorization status:

New Animal Drug Application

Summary of Product characteristics

SENTINEL SPECTRUM 2-8LBS- MILBEMYCIN OXIME, LUFENURON, PRAZIQUANTEL
TABLET, CHEWABLE
VIRBAC AH, INC
----------
SENTINEL SPECTRUM 2-8LBS
CAUTION: Federal (USA) law restricts this drug to use by or on the
order of a licensed veterinarian.
DES CRIPTION
SENTINEL® SPECTRUM® is available in four strengths in color-coded
packages for oral
administration to dogs and puppies according to their weight. Each
chewable flavored tablet is
formulated to provide a minimum of 0.23 mg/pound (0.5 mg/kg) of
milbemycin oxime, 4.55 mg/pound
(10 mg/kg) body weight of lufenuron, and 2.28 mg/pound (5mg/kg) of
praziquantel.
Milbemycin oxime consists of the oxime derivatives of
5-didehydromilbemycins in the ratio of
approximately 80% A (C
H NO , MW 555.71) and 20% A (C
H NO , MW 541.68). Milbemycin
oxime is classified as a macrocyclic anthelmintic.
Lufenuron is a benzoylphenylurea derivative with the following
chemical composition:
N-[2,5-dichloro-4-(1,1,2,3,3,3, -
hexafluoropropoxy)-phenylaminocarbonyl-2,6- difluorobenzamide
(C
H Cl
F N O , MW 551.15). Benzoylphenylurea compounds, including lufenuron,
are classified as
insect development inhibitors (lDIs).
Praziquantel is an isoquinolone anthelmintic with the chemical name
2-(Cyclohexylcarbonyl)-1 ,2,3,6,7,-
11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one.
INDICATIONS
SENTINEL SPECTRUM is indicated for the prevention of heartworm disease
caused by _Dirofilaria_
_immitis_;for the prevention and control of flea populations
(_Ctenocephalides felis_); and for the treatment
and control of adult roundworm (_Toxocara canis, Toxascaris leonina_),
adult hookworm (_Ancylostoma_
_canium_), adult whipworm (_Trichuris vulpis_), and adult tapeworm
(_Taenia pisiformis, Echinococcus_
_multilocularis_ and _Echinococcus granulosus_) infections in dogs and
puppies, two pounds of body weight
or greater and six weeks of age and older.
DOSAGE AND ADMINISTRATION
SENTINEL SPECTRUM should be administered orally, once every month, at
the minimum dosage of
0.23 mg/lb (0.5 mg/kg) milbemycin oxime, 4.55 mg/lb (10