United States - English - NLM (National Library of Medicine)

actavis pharma, inc. - hydroxocobalamin acetate (unii: s535m27n3q) (hydroxocobalamin - unii:q40x8h422o) - hydroxocobalamin 1000 ug in 1 ml - - pernicious anemia, both uncomplicated and accompanied by nervous system involvement. pernicious anemia, both uncomplicated and accompanied by nervous system involvement. - dietary deficiency of vitamin b12 , occurring in strict vegetarians and in their breast-fed infants. (isolated vitamin b12 deficiency is very rare). dietary deficiency of vitamin b12 , occurring in strict vegetarians and in their breast-fed infants. (isolated vitamin b12 deficiency is very rare). - malabsorption of vitamin b12 , resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates vitamin b12 absorption. these conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). folate deficiency in these patients is usually more severe than vitamin b12 deficiency. malabsorption of vitamin b12 , resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates vitamin b12 absorption. these conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). folate deficiency in these patients is usually more severe than vitamin b12 deficiency. - inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). total gastrectomy always produces vitamin b12 deficiency. structural lesions leading to vitamin b12 deficiency include regional ileitis, ileal resections, malignancies, etc. inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). total gastrectomy always produces vitamin b12 deficiency. structural lesions leading to vitamin b12 deficiency include regional ileitis, ileal resections, malignancies, etc. - competition for vitamin b12 by intestinal parasites or bacteria. the fish tapeworm (diphyllobothrium latum) absorbs huge quantities of vitamin b12 and infested patients often have associated gastric atrophy. the blind-loop syndrome may produce deficiency of vitamin b12 or folate. competition for vitamin b12 by intestinal parasites or bacteria. the fish tapeworm (diphyllobothrium latum) absorbs huge quantities of vitamin b12 and infested patients often have associated gastric atrophy. the blind-loop syndrome may produce deficiency of vitamin b12 or folate. - inadequate utilization of vitamin b12 . this may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia. inadequate utilization of vitamin b12 . this may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia. - for the schilling test. for the schilling test.

Ireland - English - HPRA (Health Products Regulatory Authority)

laboratorios basi industria farmaceutica s.a. - hydroxocobalamin chloride - solution for injection - hydroxocobalamin

New Zealand - English - Medsafe (Medicines Safety Authority)

boucher & muir (new zealand) limited t/a bnm group - hydroxocobalamin acetate 1 mg/ml - solution for injection - 1 mg/ml - active: hydroxocobalamin acetate 1 mg/ml excipient: acetic acid sodium acetate sodium chloride water for injection - addisonian pernicious anaemia. prophylaxis and treatment of other macrocytic anaemias associated with vitamin b12 deficiency. tobacco amblyopia and leber's optic atrophy.

Ireland - English - HPRA (Health Products Regulatory Authority)

g.l. pharma gmbh - hydroxocobalamin - solution for injection - 1 milligram(s)/millilitre - vitamin b12 (cyanocobalamin and analogues); hydroxocobalamin

Malta - English - Medicines Authority

mercury pharmaceuticals limited capital house, 85 king william street, london ec4n 7bl, united kingdom - hydroxocobalamin acetate - solution for injection - hydroxocobalamin acetate 1 mg/ml - antianemic preparations

United States - English - NLM (National Library of Medicine)

meridian medical technologies, inc. - hydroxocobalamin (unii: q40x8h422o) (hydroxocobalamin - unii:q40x8h422o) - hydroxocobalamin 5 g in 250 ml - cyanokit is indicated for the treatment of known or suspected cyanide poisoning. none risk summary available data from cases reported in the published literature and postmarketing surveillance with cyanokit use in pregnant women are insufficient to identify a drug-associated risk for major birth defects, miscarriage, or adverse maternal and fetal outcomes. there are risks to the pregnant woman and fetus associated with untreated cyanide poisoning (see clinical considerations) . in animal studies, hydroxocobalamin administered to pregnant rats and rabbits during the period of organogenesis caused skeletal and soft tissue abnormalities, including alterations in the central nervous system, at exposures similar to human exposures at the therapeutic dose (see data) . the estimated background risk of major birth defects and miscarriage for the indicated population is unknown. all pregnancies have a background risk of birth defect, loss, or other adverse outcomes. in the u.s. general population, the estimated backgr

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

elanco australasia pty ltd - hydroxocobalamin present as hydroxocobalamin acetate - parenteral liquid/solution/suspension - hydroxocobalamin present as hydroxocobalamin acetate vitamin-b12 active 2000.0 iu/ml - nutrition & metabolism - calf | cow | lamb | sheep | beef calf | bovine | calf - poddy | calf - preweaning | calf - sucker | dairy calf | ewe | female ca - vitamin b12 deficiency | anaemia | cobalt deficiency

Australia - English - Department of Health (Therapeutic Goods Administration)

pfizer australia pty ltd - hydroxocobalamin chloride, quantity: 1.027 mg - injection, solution - excipient ingredients: water for injections; acetic acid; sodium chloride - the approved indications for hydroxocobalamin injection are for prophylaxis and treatment of pernicious (addisonian) anaemia and other macrocytic anaemias associated with vitamin b12 deficiency. treatment of optic neuropathies such as tobacco amblyopia and leber's optic atrophy.

Australia - English - Department of Health (Therapeutic Goods Administration)

aspen pharmacare australia pty ltd - hydroxocobalamin chloride, quantity: 1 mg/ml - injection, solution - excipient ingredients: water for injections; sodium chloride - prophylaxis and treatment of pernicious (addisonian) anaemia and other macrocytic anaemias associated with vitaminb12 deficiency. treatment of optic neuropathies such as tobacco amblyopia and leber's optic atrophy.

United Kingdom - English - MHRA (Medicines & Healthcare Products Regulatory Agency)

advanz pharma - hydroxocobalamin - solution for injection - 1mg/1ml