juluca- dolutegravir sodium and rilpivirine hydrochloride tablet, film coated
viiv healthcare company - dolutegravir sodium (unii: 1q1v9v5wyq) (dolutegravir - unii:dko1w9h7m1), rilpivirine hydrochloride (unii: 212wax8kdd) (rilpivirine - unii:fi96a8x663) - dolutegravir 50 mg - juluca is indicated as a complete regimen for the treatment of human immunodeficiency virus type 1 (hiv-1) infection in adults to replace the current antiretroviral regimen in those who are virologically suppressed (hiv-1 rna less than 50 copies per ml) on a stable antiretroviral regimen for at least 6 months with no history of treatment failure and no known substitutions associated with resistance to the individual components of juluca. juluca is contraindicated in patients: • with previous hypersensitivity reaction to dolutegravir or rilpivirine [see warnings and precautions (5.1)] . • receiving dofetilide due to the potential for increased dofetilide plasma concentrations and the risk for serious and/or life-threatening events [see drug interactions (7)] . • receiving other coadministered drugs in table 1 that significantly decrease rilpivirine plasma concentrations [see drug interactions (7), clinical pharmacology (12.3)] . drug class contraindicated drugs in class clinical comment antia
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viiv healthcare b.v. - dolutegravir sodium, rilpivirine hydrochloride - hiv infections - antivirals for systemic use - juluca is indicated for the treatment of human immunodeficiency virus type 1 (hiv-1) infection in adults who are virologically-suppressed (hiv-1 rna
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