brinzolamida, timolol maleate - search results

United States - English - NLM (National Library of Medicine)

brinzolamide suspension/ drops

oceanside pharmaceuticals. - brinzolamide (unii: 9451z89515) (brinzolamide - unii:9451z89515) - brinzolamide ophthalmic suspension is a carbonic anhydrase inhibitor indicated in the treatment of elevated intraocular pressure (iop) in patients with ocular hypertension or open-angle glaucoma. brinzolamide ophthalmic suspension is contraindicated in patients who are hypersensitive to any component of this product. risk summary there are no adequate and well-controlled studies in pregnant women to inform drug-associated risk. in reproductive toxicity studies, brinzolamide administered orally to rats induced fetal toxicity at 375-times the recommended human ophthalmic dose (rhod) based on mg/kg. in rabbits, no fetal toxicity was observed following oral administration (see data) . the background risk of major birth defects and miscarriage for the indicated population is unknown; however, in the u.s. general population, the estimated background risk of major birth defects is 2% to 4%, and of miscarriage is 15% to 20%, of clinically recognized pregnancies. data animal data embryo-fetal studies were conducted in

Israel - English - Ministry of Health

azopt 1%

novartis israel ltd - brinzolamide - ophthalmic suspension - brinzolamide 1 % - brinzolamide - brinzolamide - alcon azopt is indicated to decrease elevated intraocular pressure in: ocular hypertension open-angle glaucoma as monotherapy in patients unresponsive to beta-blockers or in patients in whom beta-blockers are contra-indicated or as adjunctive therapy to beta-blockers.

New Zealand - English - Medsafe (Medicines Safety Authority)

azarga

novartis new zealand ltd - brinzolamide 10 mg/ml (a 2% overage is applied during manufacture); ; timolol maleate 6.8 mg/ml equivalent to 5 mg/ml (0.5%) timolol as free base; - eye drops, suspension - 1%/0.5% - active: brinzolamide 10 mg/ml (a 2% overage is applied during manufacture) timolol maleate 6.8 mg/ml equivalent to 5 mg/ml (0.5%) timolol as free base excipient: benzalkonium chloride carbomer disodium edetate hydrochloric acid mannitol purified water sodium chloride sodium hydroxide tyloxapol - azarga is indicated for the decrease of intraocular pressure (iop) in patients with open-angle glaucoma or ocular hypertension for whom monotherapy with either component provides insufficient iop reduction

Canada - English - Health Canada

azarga suspension

novartis pharmaceuticals canada inc - timolol (timolol maleate); brinzolamide - suspension - 0.5%; 1% - timolol (timolol maleate) 0.5%; brinzolamide 1% - beta-adrenergic agents