United States - English - NLM (National Library of Medicine)

proficient rx lp - ipratropium bromide (unii: j697uz2a9j) (ipratropium - unii:gr88g0i6ul) - ipratropium bromide anhydrous 0.5 mg in 2.5 ml - ipratropium bromide inhalation solution administered either alone or with other bronchodilators, especially beta adrenergics, is indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. ipratropium bromide is contraindicated in known or suspected cases of hypersensitivity to ipratropium bromide, or to atropine and its derivatives. ipratropium bromide   inhalation solution 0.02%   read complete instructions carefully before using. note: use only as directed by your physician.  more frequent administration or higher  doses are not recommended. ipratropium  bromide inhalation solution can be mixed in  the nebulizer with albuterol or metaproterenol  if used within one hour but not with  other drugs. drug stability and safety of  ipratropium bromide inhalation solution  when mixed with other drugs in the nebulizer  have not been established.   store between 59°f (15°c) and 86°f (30°c). protect from l

United States - English - NLM (National Library of Medicine)

actavis pharma, inc. - ipratropium bromide (unii: j697uz2a9j) (ipratropium - unii:gr88g0i6ul) - ipratropium bromide anhydrous 0.5 mg in 2.5 ml - ipratropium bromide inhalation solution administered either alone or with other bronchodilators, especially beta adrenergics, is indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. ipratropium bromide is contraindicated in known or suspected cases of hypersensitivity to ipratropium bromide, or to atropine and its derivatives. ipratropium bromide   inhalation solution 0.02%   read complete instructions carefully before using. - twist open the top of one unit dose vial and squeeze the contents into the nebulizer reservoir (figure 1). - connect the nebulizer reservoir to the mouthpiece or face mask (figure 2). - connect the nebulizer to the compressor. - sit in a comfortable, upright position; place the mouthpiece in your mouth (figure 3) or put on the face mask and turn on the compressor. if a face mask is used, care should be taken to avoid leakage around the mask as temporary blurring of vi

United States - English - NLM (National Library of Medicine)

sandoz inc. - ipratropium bromide (unii: j697uz2a9j) (ipratropium - unii:gr88g0i6ul) - ipratropium bromide 0.5 mg in 2.5 ml - ipratropium bromide inhalation solution administered either alone or with other bronchodilators, especially beta adrenergics, is indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. ipratropium bromide is contraindicated in known or suspected cases of hypersensitivity to ipratropium bromide, or to atropine and its derivatives. ipratropium bromide inhalation solution, 0.02% read complete instructions carefully before using. - twist open the top of one unit dose vial and squeeze the contents into the nebulizer reservoir. (figure 1). - connect the nebulizer reservoir to the mouthpiece or face mask (figure 2). - connect the nebulizer to the compressor. - sit in a comfortable, upright position; place the mouthpiece in your mouth (figure 3) or put on the face mask and turn on the compressor. if a face mask is used, care should be taken to avoid leakage around the mask as temporary blurring of visio

United States - English - NLM (National Library of Medicine)

mylan pharmaceuticals inc. - ipratropium bromide (unii: j697uz2a9j) (ipratropium - unii:gr88g0i6ul) - ipratropium bromide anhydrous 0.5 mg in 2.5 ml - ipratropium bromide inhalation solution administered either alone or with other bronchodilators, especially beta adrenergics, is indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. ipratropium bromide is contraindicated in known or suspected cases of hypersensitivity to ipratropium bromide, or to atropine and its derivatives. ipratropium bromide inhalation solution, 0.02% read complete instructions carefully before using. note: use only as directed by your physician. more frequent administration or higher doses are not recommended. ipratropium bromide inhalation solution can be mixed in the nebulizer with albuterol or metaproterenol if used within one hour but not with other drugs. drug stability and safety of ipratropium bromide inhalation solution when mixed with other drugs in the nebulizer have not been established. store between 59°f (15°c) and 86°f (30°). protect from light. store u

United States - English - NLM (National Library of Medicine)

ritedose pharmaceuticals, llc - ipratropium bromide (unii: j697uz2a9j) (ipratropium - unii:gr88g0i6ul) - ipratropium bromide anhydrous 0.5 mg in 2.5 ml - ipratropium bromide inhalation solution administered either alone or with other bronchodilators, especially beta adrenergics, is indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. ipratropium bromide is contraindicated in known or suspected cases of hypersensitivity to ipratropium bromide, or to atropine and its derivatives. ipratropium bromide inhalation solution 0.02% read complete instructions carefully before using. - twist open the top of one unit dose vial and squeeze the contents into the nebulizer reservoir. (figure 1). - connect the nebulizer reservoir to the mouthpiece or face mask (figure 2). - connect the nebulizer to the compressor. - sit in a comfortable, upright position; place the mouthpiece in your mouth (figure 3) or put on the face mask and turn on the compressor. if a face mask is used, care should be taken to avoid leakage around the mask as temporary blurring of vision, pupil enlargement, precipitation or worsening of narrow angle glaucoma, or eye pain may occur if the solution comes into direct contact with the eyes. - breathe as calmly, deeply, and evenly as possible until no more mist is formed in the nebulizer chamber (about 5 to 15 minutes). at this point, the treatment is finished. - clean the nebulizer (see manufacturer's instructions). note: use only as directed by your physician. more frequent administration or higher doses are not recommended. ipratropium bromide inhalation solution can be mixed in the nebulizer with albuterol or metaproterenol if used within one hour but not with other drugs. drug stability and safety of ipratropium bromide inhalation solution when mixed with other drugs in the nebulizer have not been established. store between 59°f (15°c) and 86°f (30°). protect from light. store unused vials in the foil pouch. additional instructions: ____________________________________ ____________________________________ ____________________________________ ____________________________________ ____________________________________ ____________________________________ ____________________________________

United States - English - NLM (National Library of Medicine)

aidarex pharmaceuticals llc - ipratropium bromide (unii: j697uz2a9j) (ipratropium - unii:gr88g0i6ul) - ipratropium bromide anhydrous 0.5 mg in 2.5 ml - ipratropium bromide inhalation solution administered either alone or with other bronchodilators, especially beta adrenergics, is indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. ipratropium bromide is contraindicated in known or suspected cases of hypersensitivity to ipratropium bromide, or to atropine and its derivatives. ipratropium bromide inhalation solution 0.02% read complete instructions carefully before using. - 1.twist open the top of one unit dose vial and squeeze the contents into the nebulizer reservoir. (figure 1). - 2.connect the nebulizer reservoir to the mouthpiece or face mask (figure 2). - 3.connect the nebulizer to the compressor. - 4.sit in a comfortable, upright position; place the mouthpiece in your mouth (figure 3) or put on the face mask and turn on the compressor. if a face mask is used, care should be taken to avoid leakage around the mask as tempo

United States - English - NLM (National Library of Medicine)

lupin pharmaceuticals, inc. - tiotropium bromide monohydrate (unii: l64sxo195n) (tiotropium - unii:0eb439235f) - tiotropium bromide inhalation powder is indicated for the long-term, once-daily, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (copd), including chronic bronchitis and emphysema. tiotropium bromide inhalation powder is indicated to reduce exacerbations in copd patients. tiotropium bromide inhalation powder is contraindicated in patients with a hypersensitivity to tiotropium, ipratropium, or any components of this product [see warnings and precautions (5.2)] . in clinical trials and postmarketing experience with tiotropium bromide inhalation powder, immediate hypersensitivity reactions, including angioedema (including swelling of the lips, tongue, or throat), itching, or rash have been reported [see warnings and precautions (5.2)] . risk summary the limited human data with tiotropium bromide inhalation powder use during pregnancy are insufficient to inform a drug-associated risk of adverse pregnancy-related outcomes. based on animal reproduction studies, no structural abnormalities were observed when tiotropium was administered by inhalation to pregnant rats and rabbits during the period of organogenesis at doses 790 and 8 times, respectively, the maximum recommended human daily inhalation dose (mrhdid). increased post-implantation loss was observed in rats and rabbits administered tiotropium at maternally toxic doses 430 times and 40 times the mrhdid, respectively [see data]. the estimated background risk of major birth defects and miscarriage for the indicated population is unknown. all pregnancies have a background risk of birth defect, loss or other adverse outcomes. in the u.s. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively. data animal data in 2 separate embryo-fetal development studies, pregnant rats and rabbits received tiotropium during the period of organogenesis at doses up to approximately 790 and 8 times the mrhdid, respectively (on a mcg/m2 basis at inhalation doses of 1471 and 7 mcg/kg/day in rats and rabbits, respectively). no evidence of structural abnormalities was observed in rats or rabbits. however, in rats, tiotropium caused fetal resorption, litter loss, decreases in the number of live pups at birth and the mean pup weights, and a delay in pup sexual maturation at tiotropium doses of approximately 40 times the mrhdid (on a mcg/m2 basis at a maternal inhalation dose of 78 mcg/kg/day). in rabbits, tiotropium caused an increase in post-implantation loss at a tiotropium dose of approximately 430 times the mrhdid (on a mcg/m2 basis at a maternal inhalation dose of 400 mcg/kg/day). such effects were not observed at approximately 5 and 95 times the mrhdid, respectively (on a mcg/m2 basis at inhalation doses of 9 and 88 mcg/kg/day in rats and rabbits, respectively). risk summary there are no data on the presence of tiotropium in human milk, the effects on the breastfed infant, or the effects on milk production. tiotropium is present in milk of lactating rats; however, due to species-specific differences in lactation physiology, the clinical relevance of these data are not clear [see data] . the developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for tiotropium bromide inhalation powder and any potential adverse effects on the breastfed child from tiotropium bromide inhalation powder or from the underlying maternal condition. data the distribution of tiotropium bromide into milk was investigated after a single intravenous administration of 10 mg/kg to lactating rats. tiotropium and/or its metabolites are present in the milk of lactating rats at concentrations above those in plasma. tiotropium bromide inhalation powder is not indicated for use in children. the safety and effectiveness of tiotropium bromide inhalation powder in pediatric patients have not been established. based on available data, no adjustment of tiotropium bromide inhalation powder dosage in geriatric patients is warranted [see clinical pharmacology (12.3)]. of the total number of patients who received tiotropium bromide inhalation powder in the 1-year clinical trials, 426 were <65 years, 375 were 65 to 74 years, and 105 were ≥75 years of age. within each age subgroup, there were no differences between the proportion of patients with adverse events in the tiotropium bromide inhalation powder and the comparator groups for most events. dry mouth increased with age in the tiotropium bromide inhalation powder group (differences from placebo were 9.0%, 17.1%, and 16.2% in the aforementioned age subgroups). a higher frequency of constipation and urinary tract infections with increasing age was observed in the tiotropium bromide inhalation powder group in the placebo-controlled studies. the differences from placebo for constipation were 0%, 1.8%, and 7.8% for each of the age groups. the differences from placebo for urinary tract infections were –0.6%, 4.6%, and 4.5%. no overall differences in effectiveness were observed among these groups. patients with moderate to severe renal impairment (creatinine clearance of <60 ml/min) treated with tiotropium bromide inhalation powder should be monitored closely for anticholinergic side effects [see dosage and administration (2), warnings and precautions (5.6), and clinical pharmacology (12.3)] . the effects of hepatic impairment on the pharmacokinetics of tiotropium were not studied.

United States - English - NLM (National Library of Medicine)

medical supply distribution, llc. - ipratropium bromide (unii: j697uz2a9j) (ipratropium - unii:gr88g0i6ul), albuterol sulfate (unii: 021sef3731) (albuterol - unii:qf8svz843e) - ipratropium bromide anhydrous 0.5 mg in 3 ml - indications and usage   ipratropium bromide and albuterol sulfate inhalation solution is indicated for the treatment of bronchospasm associated with copd in patients requiring more than one bronchodilator. contraindications   ipratropium bromide and albuterol sulfate inhalation solution is contraindicated in patients with a history of  hypersensitivity to any of its components, or to atropine and its derivatives. read this patient information completely every time your prescription is filled as information may have changed. keep these instructions with your medication as you may want to read them again. ipratropium bromide and albuterol sulfate inhalation solution should only be used under the direction of a physician. your physician and pharmacist have more information about ipratropium bromide and albuterol sulfate inhalation solution and the condition for which it has been prescribed. contact them if you have additional questions. store ipratropium bromide and albuterol sulfate inhalation solution between

United States - English - NLM (National Library of Medicine)

golden state medical supply, inc. - albuterol sulfate (unii: 021sef3731) (albuterol - unii:qf8svz843e), ipratropium bromide (unii: j697uz2a9j) (ipratropium - unii:gr88g0i6ul) - ipratropium bromide anhydrous 0.5 mg in 3 ml - ipratropium bromide and albuterol sulfate inhalation solution is indicated for the treatment of bronchospasm associated with copd in patients requiring more than one bronchodilator. ipratropium bromide and albuterol sulfate inhalation solution is contraindicated in patients with a history of hypersensitivity to any of its components, or to atropine and its derivatives.

United States - English - NLM (National Library of Medicine)

nucare pharmaceuticals,inc. - ipratropium bromide (unii: j697uz2a9j) (ipratropium - unii:gr88g0i6ul) - ipratropium bromide inhalation solution administered either alone or with other bronchodilators, especially beta adrenergics, is indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. ipratropium bromide is contraindicated in known or suspected cases of hypersensitivity to ipratropium bromide, or to atropine and its derivatives. ipratropium bromide   inhalation solution 0.02%   read complete instructions carefully before using. - twist open the top of one unit dose vial and squeeze the contents into the nebulizer reservoir (figure 1). - connect the nebulizer reservoir to the mouthpiece or face mask (figure 2). - connect the nebulizer to the compressor. - sit in a comfortable, upright position; place the mouthpiece in your mouth (figure 3) or put on the face mask and turn on the compressor. if a face mask is used, care should be taken to avoid leakage around the mask as temporary blurring of v