United States - English - NLM (National Library of Medicine)

hospira, inc. - ketamine hydrochloride (unii: o18yuo0i83) (ketamine - unii:690g0d6v8h) - ketamine 100 mg in 1 ml - ketamine hydrochloride injection is indicated: risk summary there are no adequate and well-controlled studies of ketamine hydrochloride injection in pregnant women. in animal reproduction studies in rats developmental delays (hypoplasia of skeletal tissues) were noted at 0.3 times the human intramuscular dose of 10 mg/kg. in rabbits, developmental delays and increased fetal resorptions were noted at 0.6 times the human dose. published studies in pregnant primates demonstrate that the administration of anesthetic and sedation drugs that block nmda receptors and/or potentiate gaba activity during the period of peak brain development increases neuronal apoptosis in the developing brain of the offspring when used for longer than 3 hours. there are no data on pregnancy exposures in primates corresponding to periods prior to the third trimester in humans. the estimated background risk of major birth defects and miscarriage for the indicated population is unknown. all pregnancies have a background risk of birth defe

United States - English - NLM (National Library of Medicine)

putney, inc. - ketamine hydrochloride (unii: o18yuo0i83) (ketamine - unii:690g0d6v8h) - ketamine 100 mg in 1 ml - indications ketamine hydrochloride injection, usp may be used in cats for restraint or as the sole anesthetic agent for diagnostic or minor, brief, surgical procedures that do not require skeletal muscle relaxation. it may be used in subhuman primates for restraint. contraindications ketamine hydrochloride injection, usp is contraindicated in cats and subhuman primates suffering from renal or hepatic insufficiency. ketamine hydrochloride injection, usp is detoxified by the liver and excreted by the kidneys; therefore, any preexistent hepatic or renal pathology or impairment of function can be expected to result in prolonged anesthesia; related fatalities have been reported.

Israel - English - Ministry of Health

pharma medis - ketamine as hydrochloride - solution for injection / infusion - ketamine as hydrochloride 50 mg/ml - ketamine - as the sole anaesthetic agent for diagnostic and surgical procedures. when used by intravenous or intramuscular injection, ketamine-hameln is best suited for short procedures. with additional doses, or by intravenous infusion, ketamine-hameln can be used for longer procedures. if skeletal muscle relaxation is desired, a muscle relaxant should be used and respiration should be supported.for the induction of anesthesia prior to the administration of other general anesthetic agents.to supplement other anesthetic agents.specific areas of application or types of procedures:when the intramuscular route of administration is preferred.debridement, painful dressings, and skin grafting in burned patients, as well as other superficial surgical procedures.neurodiagnostic procedures such as pneumoencephalograms, ventriculograms, myelograms, and lumbar punctures.diagnostic and operative procedures of the eye, ear, nose, and mouth, including dental extractions.note: eye movements may persist during ophthalmological procedures. anaesthesia in poor-risk patients with depression of vital functions or where depression of vital functions must be avoided, if at all possible. orthopaedic procedures such as closed reductions, manipulations, femoral pinning, amputations, and biopsies. sigmoidoscopy and minor surgery of the anus and rectum, circumcision and pilonidal sinus. cardiac catheterization procedures.caesarian section; as an induction agent in the absence of elevated blood pressure. anaesthesia in the asthmatic patient, either to minimise the risks of an attack of bronchospasm developing, or in the presence of bronchospasm where anaesthesia cannot be delayed.

Australia - English - Department of Health (Therapeutic Goods Administration)

interpharma pty ltd - ketamine hydrochloride, quantity: 57.67 mg/ml (equivalent: ketamine, qty 50 mg/ml) - injection, solution - excipient ingredients: water for injections; sodium hydroxide; hydrochloric acid - ketamine interpharma? is recommended:,1. as the sole anaesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. ketamine interpharma ? is best suited for short procedures and it can be used with additional doses, for longer procedures; 2. for the induction of anaesthesia prior to the administration of other general anaesthetic agents; 3. to supplement low-potency agents, such as nitrous oxide.

Australia - English - Department of Health (Therapeutic Goods Administration)

interpharma pty ltd - ketamine hydrochloride, quantity: 57.67 mg/ml (equivalent: ketamine, qty 50 mg/ml) - injection, solution - excipient ingredients: hydrochloric acid; water for injections; sodium hydroxide - ketamine interpharma? is recommended:,1. as the sole anaesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. ketamine interpharma ? is best suited for short procedures and it can be used with additional doses, for longer procedures; 2. for the induction of anaesthesia prior to the administration of other general anaesthetic agents; 3. to supplement low-potency agents, such as nitrous oxide.

Australia - English - Department of Health (Therapeutic Goods Administration)

interpharma pty ltd - ketamine hydrochloride, quantity: 57.67 mg/ml (equivalent: ketamine, qty 50 mg/ml) - injection, solution - excipient ingredients: sodium hydroxide; water for injections; hydrochloric acid - ketamine interpharma? is recommended:,1. as the sole anaesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. ketamine interpharma ? is best suited for short procedures and it can be used with additional doses, for longer procedures; 2. for the induction of anaesthesia prior to the administration of other general anaesthetic agents; 3. to supplement low-potency agents, such as nitrous oxide.

Israel - English - Ministry of Health

a.l. medi-market ltd. - ketamine as hydrochloride - solution for injection / infusion - ketamine as hydrochloride 10 mg / 1 ml - ketamine - ketamine g.l. 10 mg/ml is indicated as the sole anaesthetic agent for diagnostic and surgical procedures. when used by intravenous or intramuscular injection, ketamine g.l. is best suited for short procedures. with additional doses, or by intravenous infusion, ketamine g.l. can be used for longer procedures. if skeletal muscle relaxation is desired a muscle relaxant should be used and respiration should be supported. for the induction of anaesthesia prior to the administration of other general anaesthetic agents. to supplement other anaesthetic agents. specific areas of application or types of procedure: when the intramuscular route of administration is preferred. debridement, painful dressings and skin grafting in burned patients as well as other superficial surgical procedures. neurodiagnostic procedures such as pneumoencephalograms, ventriculograms, myelograms and lumbar punctures. diagnostic and operative procedures of the eye, ear, nose and mouth including dental extractions.( note: eye movement may persist during ophthalmological procedures). anaesthesia in poor-risk patients with depression of vital functions or where depression of vital functions must be avoided if at all possible. orthopaedic procedures such as closed reduction, manipulation femoral pinning, amputations and biopsies. sigmoidoscopy and minor surgery of the anus and rectum, circumcision and pilonidal sinus. cardiac catheterization procedures. caesarian section: as an induction agent in the absence of elevated blood pressure. anaesthesia in the asthmatic patient, either to minimise the risk of an attack of bronchospasm developing or in the presence of bronchospasm where anaesthesia cannot be delayed.

New Zealand - English - Medsafe (Medicines Safety Authority)

baxter healthcare ltd - ketamine hydrochloride 115.34 mg/ml equivalent to ketamine 100 mg/ml - solution for injection - 100 mg/ml - active: ketamine hydrochloride 115.34 mg/ml equivalent to ketamine 100 mg/ml excipient: nitrogen water for injection - ketamine-baxter is recommended: 1. as the sole anaesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. ketamine-baxter is best suited for short procedures and it can be used with additional doses, for longer procedures; 2. for the induction of anaesthesia prior to the administration of other general anaesthetic agents; 3. to supplement low-potency agents, such as nitrous oxide.

Israel - English - Ministry of Health

propharm ltd - ketamine as hydrochloride - solution for injection / infusion - ketamine as hydrochloride 10 mg/ml - ketamine - * as the sole anaesthetic agent for diagnostic and surgical procedures.when used by intravenous or intramuscular injection, ketamine propharm 10mg/ml is best suited for short procedures. with additional doses, or by intravenous infusion, ketamine propharm 10mg/ml can be used for longer procedures. if skeletal muscle relaxation is desired a muscle relaxant should be used and respiration should be supported.* for the induction of anaesthesia prior to the administration of other general anaesthetic agents.* to supplement other anaesthetic agents.specific areas of application or types of procedure: when the intramuscular route of administration is preferred.* debridement, painful dressings and skin grafting in burned patients as well as other superficial surgical procedures.* neurodiagnostic procedures such as pneumoencephalograms, ventriculograms, myelograms and lumbar punctures.* diagnostic and operative procedures of the eye, ear, nose and mouth including dental extractions.( note: eye movement may persist during ophthalmological procedures).* anaesthesia in poor-risk patients with depression of vital functions or where depression of vital functions must be avoided if at all possible.* orthopaedic procedures such as closed reduction, manipulation femoral pinning, amputations and biopsies.* sigmoidoscopy and minor surgery of the anus and rectum, circumcision and pilonidal sinus. * cardiac catheterization procedures.* caesarian section: as an induction agent in the absence of elevated blood pressure.* anaesthesia in the asthmatic patient, either to minimise the risk of an attack of bronchospasm developing or in the presence of bronchospasm where anaesthesia cannot be delayed.

Ireland - English - HPRA (Health Products Regulatory Authority)

sintetica ireland limited - esketamine - solution for injection/infusion - 25 milligram(s)/millilitre - esketamine