Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

pacific agriscience pty ltd - metsulfuron-methyl - water dispersible granule - metsulfuron-methyl urea-sulfonyl active 600.0 g/kg - herbicide - barley | cereal rye | commercial area - general | commercial/industrial land | domestic area - outdoors | flood plain | forest | - african turnip weed | alligator weed | amsinckia,yellow burrweed or burr grass | annual clovers | apple box | australian or native blackthorn | ball mustard | bellyache bush | bitou bush or boneseed | blackberry | blackberry - rubus spp. | blakely's red gum or gum | boggabri weed | bracken | bridal creeper | calomba daisy | cape tulip | capeweed | capeweed & wild radish(joint infestation | charlock | chickweed | chicory | climbing buckwheat | clover | crofton weed | cutleaf mignonette | darling pea | deadnettle | denseflower fumitory | dock | dock - suppression | erodium spp. | erodium, crowfoot or storksbill | fennel | furze or gorse | golden dodder | great mullein | gum - peppermint | hare's-ear or treacle mustard | hawthorn | indian hedge mustard | inkweed | japanese sunflower | kangaroo thorn | lantana - lantana camara | lincoln weed, sand rocket or mustard | lupins | mallee catchfly | medic | messmate stringybark | mimosa pigra | mistflower or creeping crofton weed | new zealand spinach | noogoora burr |

Singapore - English - HSA (Health Sciences Authority)

aguettant asia pacific pte. ltd. - zinc gluconate eqv elemental zinc - infusion, solution concentrate - zinc gluconate eqv elemental zinc 1mg/ml

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

pacific agriscience pty ltd - propiconazole; liquid hydrocarbon - emulsifiable concentrate - propiconazole triazole active 250.0 g/l; liquid hydrocarbon solvent other 600.0 g/l - fungicide - apricot | banana | barley | boronia | oats | peanut | peppermint - oil production only | perennial ryegrass crop | pineapple | p - barley leaf scald | base or butt rot - t. paradoxa | black sigatoka | blind seed disease | blossom blight - monilinia fructicola | blossom blight - monilinia laxa | cordana leaf spot - cordana johnstonii | cordana leaf spot - cordana musae | crown rust (puccinia coronata) on oats | early leaf spot on peanut | late leaf spot on peanut | leaf rust | leaf smut on poppy | leaf speckle on banana | leaf spot or yellow sigatoka on banana | pineapple disease | powdery mildew - bulmeria graminis | prune rust | rust on boronia | rust on mint | rust on peanut | septoria leaf blotch - suppession | septoria nodorum blotch on wheat | septoria tritici blotch | spot form net blotch - pyrenophora teres | stem rust | yellow leaf spot on wheat | yellow or stripe rust | barley scald | brown rot | butt rot | ceratocystis paradoxa | peanut rust | puccinia recondita f.sp. triti | puccinia striiformis | puccinia triticina | septoria tritici | sigatoka | wheat leaf rust | yellow rust | yellow sigatoka | yellow spot

United States - English - NLM (National Library of Medicine)

pacific pharma, inc. - brimonidine tartrate (unii: 4s9cl2dy2h) (brimonidine - unii:e6gnx3hhte) - brimonidine tartrate ophthalmic solution 0.1% or 0.15% is an alpha adrenergic receptor agonist indicated for the reduction of elevated intraocular pressure (iop) in patients with open-angle glaucoma or ocular hypertension. brimonidine tartrate ophthalmic solution 0.1% and 0.15% is contraindicated in neonates and infants (under the age of 2 years). brimonidine tartrate ophthalmic solution 0.1% and 0.15% is contraindicated in patients who have exhibited a hypersensitivity reaction to any component of this medication in the past. pregnancy category b: teratogenicity studies have been performed in animals. brimonidine tartrate was not teratogenic when given orally during gestation days 6 through 15 in rats and days 6 through 18 in rabbits. the highest doses of brimonidine tartrate in rats (2.5 mg/kg/day) and rabbits (5.0 mg/kg/day) achieved auc exposure values 360- and 20-fold higher, or 260- and 15-fold higher, respectively, than similar values estimated in humans treated with brimonidine tartrate ophthalmic solution 0.1% or 0.15%, 1 drop in both eyes three times daily. there are no adequate and well-controlled studies in pregnant women; however, in animal studies, brimonidine crossed the placenta and entered into the fetal circulation to a limited extent. because animal reproduction studies are not always predictive of human response, brimonidine tartrate ophthalmic solution 0.1% and 0.15% should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus. it is not known whether brimonidine tartrate is excreted in human milk, although in animal studies, brimonidine tartrate has been shown to be excreted in breast milk. because of the potential for serious adverse reactions from brimonidine tartrate ophthalmic solution 0.1% and 0.15% in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. brimonidine tartrate ophthalmic solution 0.1% and 0.15% is contraindicated in children under the age of 2 years (see contraindications, 4.1 ). during postmarketing surveillance, apnea, bradycardia, coma, hypotension, hypothermia, hypotonia, lethargy, pallor, respiratory depression, and somnolence have been reported in infants receiving brimonidine. the safety and effectiveness of brimonidine tartrate have not been studied in children below the age of 2 years. in a well-controlled clinical study conducted in pediatric glaucoma patients (ages 2 to 7 years) the most commonly observed adverse reactions with brimonidine tartrate ophthalmic solution 0.2% dosed three times daily were somnolence (50-83% in patients ages 2 to 6 years) and decreased alertness. in pediatric patients 7 years of age (>20 kg), somnolence appears to occur less frequently (25%). approximately 16% of patients on brimonidine tartrate ophthalmic solution discontinued from the study due to somnolence.  no overall differences in safety or effectiveness have been observed between elderly and other adult patients. brimonidine tartrate ophthalmic solution 0.1% and 0.15% has not been studied in patients with hepatic impairment. brimonidine tartrate ophthalmic solution 0.1% and 0.15% has not been studied in patients with renal impairment. the effect of dialysis on brimonidine pharmacokinetics in patients with renal failure is not known.

United States - English - NLM (National Library of Medicine)

pacific pharma, inc. - levobunolol hydrochloride (unii: o90s49ldhh) (levobunolol - unii:g6317aoi7k) - levobunolol hydrochloride 2.5 mg in 1 ml - levobunolol hcl ophthalmic solution has been shown to be effective in lowering intraocular pressure and may be used in patients with chronic open-angle glaucoma or ocular hypertension. levobunolol hcl ophthalmic solution is contraindicated in those individuals with bronchial asthma or with a history of bronchial asthma, or severe chronic obstructive pulmonary disease (see warnings); sinus bradycardia; second and third degree atrioventricular block; overt cardiac failure (see warnings); cardiogenic shock; or hypersensitivity to any component of these products.

United States - English - NLM (National Library of Medicine)

pacific pharma, inc. - tazarotene (unii: 81bdr9y8ps) (tazarotene - unii:81bdr9y8ps) - tazarotene 0.5 mg in 1 g - tazarotene  cream, 0.05% and 0.1% are indicated for the topical treatment of patients with plaque psoriasis. tazarotene  cream, 0.1% is also indicated for the topical treatment of patients with acne vulgaris. tazarotene cream is contraindicated in: - pregnancy. retinoids may cause fetal harm when administered to a pregnant female [see warnings and precautions ( 5.1 ), use in specific populations ( 8.1 , 8.3 )] . - individuals who have known hypersensitivity to any of its components [see warnings and precautions ( 5.2 )] . risk summary based on data from animal reproduction studies, retinoid pharmacology, and the potential for systemic absorption, tazarotene cream may cause fetal harm when administered to a pregnant female and is contraindicated during pregnancy.  safety in pregnant females has not been established.  the potential risk to the fetus outweighs the potential benefit to the mother from tazarotene cream during pregnancy; therefore, tazarotene cream should be discontinued as soon as pregnancy is re

United States - English - NLM (National Library of Medicine)

pacific pharma, inc. - dapsone (unii: 8w5c518302) (dapsone - unii:8w5c518302) - dapsone 50 mg in 1 g - dapsone gel, 5%, is indicated for the topical treatment of acne vulgaris. none. risk summary there are no available data on dapsone gel, 5% in pregnant women to inform a drug-associated risk for adverse developmental outcomes. in animal reproduction studies, oral doses of dapsone administered to pregnant rats and rabbits during organogenesis that resulted in systemic exposures more than 250 times the systemic exposure at the maximum recommended human dose (mrhd) of dapsone gel, 5%, resulted in embryocidal effects. when orally administered to rats from the onset of organogenesis through the end of lactation at systemic exposures approximately 400 times the exposure at the mrhd, dapsone resulted in increased stillbirths and decreased pup weight [see data] . the estimated background risks of major birth defects and miscarriage for the indicated population are unknown. in the u.s. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4%

United States - English - NLM (National Library of Medicine)

pacific pharma, inc. - sulfacetamide sodium (unii: 4nrt660kjq) (sulfacetamide - unii:4965g3j0f5) - sulfacetamide sodium solution is indicated for the treatment of conjunctivitis and other superficial ocular infections due to susceptible microorganisms, and as an adjunctive in systemic sulfonamide therapy of trachoma: escherichia coli , staphylococcus  aureus , streptococcus  pneumoniae , streptococcus (viridans group), haemophilus  influenzae , klebsiella species, and enterobacter species. topically applied sulfonamides do not provide adequate coverage against neisseria species, serratia  marcescens and pseudomonas  aeruginosa . a significant percentage of staphylococcal isolates are completely resistant to sulfa drugs. sulfacetamide sodium solution is contraindicated in individuals who have a hypersensitivity to sulfonamides or to any ingredient of the preparation.

United States - English - NLM (National Library of Medicine)

pacific pharma, inc. - brimonidine tartrate (unii: 4s9cl2dy2h) (brimonidine - unii:e6gnx3hhte), timolol maleate (unii: p8y54f701r) (timolol anhydrous - unii:5jky92s7br) - brimonidine tartrate and timolol maleate ophthalmic solution 0.2%/0.5% is an alpha-adrenergic receptor agonist with a beta-adrenergic receptor inhibitor indicated for the reduction of elevated intraocular pressure (iop) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled iop; the iop-lowering of brimonidine tartrate and timolol maleate ophthalmic solution dosed twice a day was slightly less than that seen with the concomitant administration of 0.5% timolol maleate ophthalmic solution dosed twice a day and 0.2% brimonidine tartrate ophthalmic solution dosed three times per day. brimonidine tartrate and timolol maleate ophthalmic solution is contraindicated in patients with reactive airway disease including bronchial asthma; a history of bronchial asthma; severe chronic obstructive pulmonary disease [ see warnings and precautions   ( 5.1 , 5.3 ) ] . brimonidine tartrate and timolol maleate ophthalmic solution is contraindicated in patie

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

pacific agriscience pty ltd - glyphosate present as the isopropylamine salt - aqueous concentrate - glyphosate present as the isopropylamine salt glycine active 450.0 g/l - herbicide - annual grass weed - seed set control | band spraying | calomba daisy seed set control | capeweed seed set control | cotton - pre - african turnip weed | amsinckia | annual or wimmera ryegrass | annual phalaris | annual weeds | australian bluebell - w. gracilis | barbed wire grass | barley grass | barnyard or water grass | bathurst burr | bladder ketmia | boggabri weed | brome grass - bromus unioloides | browntop bent | bunch speargrass | burr medic | button grass | calomba daisy | caltrop or yellow vine | camel or afghan melon | canary grass | capeweed | carpet grass | cat's ear or flatweed | columbus grass - seedling | couch | couch grass | cudweed | deadnettle | dock | dock - seedling | erodium, crowfoot or storksbill | fumitory | giant or black pigweed | gooseberry | grain sorghum - pre harvest | hedge or wild mustard | hoary cress or whiteweed | indian hedge mustard | johnson grass | kikuyu grass | liverseed or urochloa grass | lovegrass | mexican poppy | mintweed | native millet | new zealand spinach | noogoora burr | nutgrass | nutgrass - seasonal suppression | paspalum | paterson's curse | perennial phalaris - suppression | perenn