SALECO 120 GRANULAR

Australia - English - APVMA (Australian Pesticides and Veterinary Medicines Authority)

Buy It Now

Active ingredient:
SALINOMYCIN SODIUM
Available from:
INTERNATIONAL ANIMAL HEALTH PRODUCTS PTY LTD
INN (International Name):
salinomycin as Na salt(116.6g/kg)
Pharmaceutical form:
ORAL POWDER, PRE-MIX
Composition:
SALINOMYCIN SODIUM ANTIPROTOZOAL Active 120.0 g/kg
Units in package:
25kg
Class:
VM - Veterinary Medicine
Manufactured by:
IAHP
Therapeutic group:
CATTLE - FEEDLOT | PIGS | POULTRY | BEEF | BOAR | BOVINE | BREEDERS | BROILER | CHICKENS | CHICKS | CHOOKS | DAIRY COW | DAY OLD
Therapeutic area:
ANTIBIOTIC + NUTRITIONAL
Therapeutic indications:
COCCIDIOSIS | EIMERIA SPP. | FEED ADDITIVE | EIMERIA ACERVULINA | EIMERIA BRUNETTI | EIMERIA MAXIMA | EIMERIA MIVATI | EIMERIA NECATRIX | EIMERIA TENELLA
Product summary:
Poison schedule: 6; Withholding period: WHP: Meat: Nil. Milk: DO NOT USE in an imal producing milk for human consumpti on. Eggs: DO NOT USE in birds laying eg gs for human consumption or within 7 da ys of laying where eggs or egg products are to be used for human consumption o r processing. ESI: This product does n ot have an ESI established. For advice on the ESI, contact the manufacturer on 02)9672 7944 before using this product .; Host/pest details: CATTLE - FEEDLOT: [FEED ADDITIVE]; PIGS: [FEED ADDITIVE]; POULTRY: [COCCIDIOSIS, EIMERIA SPP.]; Poison schedule: 6; Withholding period: ; Host/pest details: CATTLE - FEEDLOT: [FEED ADDITIVE]; PIGS: [FEED ADDITIVE]; POULTRY: [COCCIDIOSIS, EIMERIA SPP.]; An aid in the prevention of coccidiosis in broiler chickens & replacement birds intended for use as caged layers. For the improvement of productivity by stimulating the growth rate & increasing the feed conversion of grower/finisher pigs and feedlot beef.DO NOT feed to horses or any other animal or bird not included on this label claim. DO NOT USE in animals producing milk for human consumption. DO NOT administer to animals receiving Tiamulin (Dynamutilin)
Authorization status:
Registered
Authorization number:
53304
Authorization date:
2020-07-01

Info

pest

Verified

International Animal Health Products Pty Ltd

Chemwatch Hazard Alert Code: 3

Saleco 120 Granular

Chemwatch: 4856-62

Version No: 3.1.1.1

Safety Data Sheet according to WHS and ADG requirements

Issue Date: 16/07/2016

Print Date: 25/10/2016

S.GHS.AUS.EN

SECTION 1 IDENTIFICATION OF THE SUBSTANCE / MIXTURE AND OF THE COMPANY / UNDERTAKING

Product Identifier

Product name

Saleco 120 Granular

Other means of

identification

Not Available

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified

uses

Aids in the prevention of coccidiosis in broiler chickens and in replacement birds. Improves productivity by stimulating the

growth rate and increasing the feed conversion efficiency of grower/finisher pigs and feedlot beef cattle. Oral administration

in feed as per label directions. DO NOT USE in animals producing milk for human consumption. DO NOT USE in birds

producing eggs for human consumption. Do not administer to animals receiving Tiamulin. Care should be taken when feeding

concurrently with other microbials.

Details of the supplier of the safety data sheet

Registered company

name

International Animal Health Products Pty Ltd

Address

18 Healey Circuit Huntingwood NSW 2148 Australia

Telephone

+61 2 9672 7944

Fax

+61 2 9672 7988

Website

www.iahp.com.au

Email

info@iahp.com.au

Emergency telephone number

Association /

Organisation

Not Available

Emergency telephone

numbers

+61 2 9672 7944

Other emergency

telephone numbers

131 126 (Poisons Info. Centre Australia)

SECTION 2 HAZARDS IDENTIFICATION

Classification of the substance or mixture

HAZARDOUS CHEMICAL. NON-DANGEROUS GOODS. According to the WHS Regulations and the ADG Code.

Poisons Schedule

Classification

[1]

Acute Toxicity (Oral) Category 4, Skin Corrosion/Irritation Category 2, Serious Eye Damage Category 1, Specific target

organ toxicity - single exposure Category 3 (respiratory tract irritation)

Continued...

Legend:

1. Classified by Chemwatch; 2. Classification drawn from HSIS ; 3. Classification drawn from EC Directive 1272/2008 - Annex

Label elements

GHS label elements

SIGNAL WORD

DANGER

Hazard statement(s)

H302

Harmful if swallowed.

H315

Causes skin irritation.

H318

Causes serious eye damage.

H335

May cause respiratory irritation.

AUH066

Repeated exposure may cause skin dryness and cracking

Supplementary statement(s)

Not Applicable

Precautionary statement(s) Prevention

P271

Use only outdoors or in a well-ventilated area.

P280

Wear protective gloves/protective clothing/eye protection/face protection.

P261

Avoid breathing dust/fumes.

P270

Do not eat, drink or smoke when using this product.

Precautionary statement(s) Response

P305+P351+P338

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue

rinsing.

P310

Immediately call a POISON CENTER or doctor/physician.

P362

Take off contaminated clothing and wash before reuse.

P301+P312

IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.

Precautionary statement(s) Storage

P405

Store locked up.

P403+P233

Store in a well-ventilated place. Keep container tightly closed.

Precautionary statement(s) Disposal

P501

Dispose of contents/container in accordance with local regulations.

SECTION 3 COMPOSITION / INFORMATION ON INGREDIENTS

Substances

See section below for composition of Mixtures

Mixtures

CAS No

%[weight]

Name

471-34-1

30-60

55721-31-8

5-15

balance

Ingredients determined not to be hazardous

SECTION 4 FIRST AID MEASURES

Description of first aid measures

Eye Contact

calcium carbonate

salinomycin monosodium salt

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If this product comes in contact with the eyes:

Immediately hold eyelids apart and flush the eye continuously with running water.

Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally

lifting the upper and lower lids.

Continue flushing until advised to stop by the Poisons Information Centre or a doctor, or for at least 15 minutes.

Transport to hospital or doctor without delay.

Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.

Skin Contact

If skin contact occurs:

Immediately remove all contaminated clothing, including footwear.

Flush skin and hair with running water (and soap if available).

Seek medical attention in event of irritation.

Inhalation

If fumes or combustion products are inhaled remove from contaminated area.

Lay patient down. Keep warm and rested.

Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid

procedures.

Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket

mask as trained. Perform CPR if necessary.

Transport to hospital, or doctor, without delay.

Ingestion

IF SWALLOWED, REFER FOR MEDICAL ATTENTION, WHERE POSSIBLE, WITHOUT DELAY.

For advice, contact a Poisons Information Centre or a doctor.

Urgent hospital treatment is likely to be needed.

In the mean time, qualified first-aid personnel should treat the patient following observation and employing supportive

measures as indicated by the patient's condition.

If the services of a medical officer or medical doctor are readily available, the patient should be placed in his/her care and

a copy of the SDS should be provided. Further action will be the responsibility of the medical specialist.

If medical attention is not available on the worksite or surroundings send the patient to a hospital together with a copy of

the SDS.

Where medical attention is not immediately available or where the patient is more than 15 minutes from a hospital

or unless instructed otherwise:

INDUCE vomiting with fingers down the back of the throat, ONLY IF CONSCIOUS. Lean patient forward or place on left

side (head-down position, if possible) to maintain open airway and prevent aspiration.

NOTE: Wear a protective glove when inducing vomiting by mechanical means.

Indication of any immediate medical attention and special treatment needed

As in all cases of suspected poisoning, follow the ABCDEs of emergency medicine (airway, breathing, circulation, disability, exposure), then the ABCDEs

of toxicology (antidotes, basics, change absorption, change distribution, change elimination).

For poisons (where specific treatment regime is absent):

--------------------------------------------------------------

BASIC TREATMENT

--------------------------------------------------------------

Establish a patent airway with suction where necessary.

Watch for signs of respiratory insufficiency and assist ventilation as necessary.

Administer oxygen by non-rebreather mask at 10 to 15 L/min.

Monitor and treat, where necessary, for pulmonary oedema.

Monitor and treat, where necessary, for shock.

Anticipate seizures.

DO NOT use emetics. Where ingestion is suspected rinse mouth and give up to 200 ml water (5 ml/kg recommended) for dilution where patient is able to

swallow, has a strong gag reflex and does not drool.

--------------------------------------------------------------

ADVANCED TREATMENT

--------------------------------------------------------------

Consider orotracheal or nasotracheal intubation for airway control in unconscious patient or where respiratory arrest has occurred.

Positive-pressure ventilation using a bag-valve mask might be of use.

Monitor and treat, where necessary, for arrhythmias.

Start an IV D5W TKO. If signs of hypovolaemia are present use lactated Ringers solution. Fluid overload might create complications.

Drug therapy should be considered for pulmonary oedema.

Hypotension with signs of hypovolaemia requires the cautious administration of fluids. Fluid overload might create complications.

Treat seizures with diazepam.

Proparacaine hydrochloride should be used to assist eye irrigation.

BRONSTEIN, A.C. and CURRANCE, P.L.

EMERGENCY CARE FOR HAZARDOUS MATERIALS EXPOSURE: 2nd Ed. 1994

Treat symptomatically.

SECTION 5 FIREFIGHTING MEASURES

Extinguishing media

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There is no restriction on the type of extinguisher which may be used.

Use extinguishing media suitable for surrounding area.

Special hazards arising from the substrate or mixture

Fire Incompatibility

Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine bleaches, pool chlorine etc. as ignition may

result

Advice for firefighters

Fire Fighting

Alert Fire Brigade and tell them location and nature of hazard.

Wear breathing apparatus plus protective gloves in the event of a fire.

Prevent, by any means available, spillage from entering drains or water courses.

Use fire fighting procedures suitable for surrounding area.

Fire/Explosion Hazard

Combustible solid which burns but propagates flame with difficulty; it is estimated that most organic dusts are combustible

(circa 70%) - according to the circumstances under which the combustion process occurs, such materials may cause fires

and / or dust explosions.

Organic powders when finely divided over a range of concentrations regardless of particulate size or shape and suspended

in air or some other oxidizing medium may form explosive dust-air mixtures and result in a fire or dust explosion (including

secondary explosions).

Avoid generating dust, particularly clouds of dust in a confined or unventilated space as dusts may form an explosive

mixture with air, and any source of ignition, i.e. flame or spark, will cause fire or explosion. Dust clouds generated by the

fine grinding of the solid are a particular hazard; accumulations of fine dust (420 micron or less) may burn rapidly and

fiercely if ignited - particles exceeding this limit will generally not form flammable dust clouds; once initiated, however,

larger particles up to 1400 microns diameter will contribute to the propagation of an explosion.

Combustion products include:, carbon monoxide (CO), carbon dioxide (CO2), other pyrolysis products typical of burning

organic material May emit poisonous fumes. May emit corrosive fumes. Heating calcium carbonate at high temperatures( 825

C.) causes decomposition, releases carbon dioxide gas and leaves a residue of alkaline lime

HAZCHEM

Not Applicable

SECTION 6 ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

See section 8

Environmental precautions

See section 12

Methods and material for containment and cleaning up

Minor Spills

Clean up waste regularly and abnormal spills immediately.

Avoid breathing dust and contact with skin and eyes.

Wear protective clothing, gloves, safety glasses and dust respirator.

Use dry clean up procedures and avoid generating dust.

Major Spills

Moderate hazard.

CAUTION: Advise personnel in area.

Alert Emergency Services and tell them location and nature of hazard.

Control personal contact by wearing protective clothing.

Personal Protective Equipment advice is contained in Section 8 of the SDS.

SECTION 7 HANDLING AND STORAGE

Precautions for safe handling

Safe handling

NOTE : Do NOT pipette by mouth. Only trained personnel should be allowed to handle or use this product.

Avoid all personal contact, including inhalation.

Wear protective clothing when risk of exposure occurs.

Use in a well-ventilated area.

Prevent concentration in hollows and sumps.

Organic powders when finely divided over a range of concentrations regardless of particulate size or shape and suspended

in air or some other oxidizing medium may form explosive dust-air mixtures and result in a fire or dust explosion (including

secondary explosions)

Minimise airborne dust and eliminate all ignition sources. Keep away from heat, hot surfaces, sparks, and flame.

Establish good housekeeping practices.

Remove dust accumulations on a regular basis by vacuuming or gentle sweeping to avoid creating dust clouds.

Other information

Store in original containers.

Keep containers securely sealed.

Store in a cool, dry area protected from environmental extremes.

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Store away from incompatible materials and foodstuff containers.

Conditions for safe storage, including any incompatibilities

Suitable container

Multi-ply paper bag with sealed plastic liner or heavy gauge plastic bag.

NOTE: Bags should be stacked, blocked, interlocked, and limited in height so that they are stable and secure against sliding

or collapse. Check that all containers are clearly labelled and free from leaks. Packing as recommended by manufacturer.

Glass container is suitable for laboratory quantities

|25kg multi-walled paper bag with plastic lining.

Storage

incompatibility

Calcium carbonate:

is incompatible with acids, ammonium salts, fluorine, germanium, lead diacetate, magnesium, mercurous chloride, silicon,

silver nitrate, titanium.

Contact with acid generates carbon dioxide gas, which may pressurise and then rupture closed containers

Avoid strong acids, acid chlorides, acid anhydrides and chloroformates.

Avoid reaction with oxidising agents

SECTION 8 EXPOSURE CONTROLS / PERSONAL PROTECTION

Control parameters

OCCUPATIONAL EXPOSURE LIMITS (OEL)

INGREDIENT DATA

Source

Ingredient

Material name

TWA

STEL

Peak

Notes

Australia Exposure

Standards

calcium carbonate

Calcium carbonate

10 mg/m3

Not Available

Not Available

Not Available

EMERGENCY LIMITS

Ingredient

Material name

TEEL-1

TEEL-2

TEEL-3

calcium carbonate

Limestone; (Calcium carbonate; Dolomite)

27 mg/m3

27 mg/m3

1300 mg/m3

calcium carbonate

Carbonic acid, calcium salt

45 mg/m3

210 mg/m3

1300 mg/m3

Ingredient

Original IDLH

Revised IDLH

calcium carbonate

Not Available

Not Available

salinomycin

monosodium salt

Not Available

Not Available

Exposure controls

Appropriate

engineering controls

For potent pharmacological agents:

Powders

To prevent contamination and overexposure, no open handling of powder should be allowed.

Powder handling operations are to be done in a powders weighing hood, a glove box, or other equivalent ventilated

containment system.

In situations where these ventilated containment hoods have not been installed, a non-ventilated enclosed containment

hood should be used.

Pending changes resulting from additional air monitoring data, up to 300 mg can be handled outside of an enclosure

provided that no grinding, crushing or other dust-generating process occurs.

Unless written procedures, specific to the workplace are available, the following is intended as a guide:

For Laboratory-scale handling of Substances assessed to be toxic by inhalation.

Quantities of up to 25

grams

may be handled in Class II biological safety cabinets *;

Quantities of 25 grams to 1 kilogram

may be handled in

Class II biological safety cabinets* or equivalent containment systems;

Quantities exceeding 1 kg

may be handled either

using specific containment, a hood or Class II biological safety cabinet*,

HEPA terminated local exhaust ventilation should be considered at point of generation of dust, fumes or vapours.

The need for respiratory protection should also be assessed where incidental or accidental exposure is anticipated.

Dependent on levels of contamination, PAPR, full face air purifying devices with P2 or P3 filters or air supplied respirators

should be evaluated.

Personal protection

Eye and face

protection

When handling very small quantities of the material eye protection may not be required.

For laboratory, larger scale or bulk handling or where regular exposure in an occupational setting occurs:

Chemical goggles.

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Face shield. Full face shield may be required for supplementary but never for primary protection of eyes.

Skin protection

See Hand protection below

Hands/feet protection

The selection of suitable gloves does not only depend on the material, but also on further marks of quality which vary from

manufacturer to manufacturer. Where the chemical is a preparation of several substances, the resistance of the glove

material can not be calculated in advance and has therefore to be checked prior to the application.

The exact break through time for substances has to be obtained from the manufacturer of the protective gloves and.has to

be observed when making a final choice.

Personal hygiene is a key element of effective hand care.

Rubber gloves (nitrile or low-protein, powder-free latex, latex/ nitrile). Employees allergic to latex gloves should use nitrile

gloves in preference.

Double gloving should be considered.

PVC gloves.

Experience indicates that the following polymers are suitable as glove materials for protection against undissolved, dry

solids, where abrasive particles are not present.

polychloroprene.

nitrile rubber.

butyl rubber.

Body protection

See Other protection below

Other protection

For quantities up to 500 grams a laboratory coat may be suitable.

For quantities up to 1 kilogram a disposable laboratory coat or coverall of low permeability is recommended. Coveralls

should be buttoned at collar and cuffs.

For quantities over 1 kilogram and manufacturing operations, wear disposable coverall of low permeability and disposable

shoe covers.

Thermal hazards

Not Available

Respiratory protection

Type A-P Filter of sufficient capacity. (AS/NZS 1716 & 1715, EN 143:2000 & 149:2001, ANSI Z88 or national equivalent)

Where the concentration of gas/particulates in the breathing zone, approaches or exceeds the "Exposure Standard" (or ES), respiratory protection is

required.

Degree of protection varies with both face-piece and Class of filter; the nature of protection varies with Type of filter.

Required Minimum Protection Factor

Half-Face Respirator

Full-Face Respirator

Powered Air Respirator

up to 10 x ES

A-AUS P2

A-PAPR-AUS / Class 1 P2

up to 50 x ES

A-AUS / Class 1 P2

up to 100 x ES

A-2 P2

A-PAPR-2 P2 ^

^ - Full-face

A(All classes) = Organic vapours, B AUS or B1 = Acid gasses, B2 = Acid gas or hydrogen cyanide(HCN), B3 = Acid gas or hydrogen cyanide(HCN), E =

Sulfur dioxide(SO2), G = Agricultural chemicals, K = Ammonia(NH3), Hg = Mercury, NO = Oxides of nitrogen, MB = Methyl bromide, AX = Low boiling point

organic compounds(below 65 degC)

Respirators may be necessary when engineering and administrative controls do not adequately prevent exposures.

The decision to use respiratory protection should be based on professional judgment that takes into account toxicity information, exposure measurement

data, and frequency and likelihood of the worker's exposure - ensure users are not subject to high thermal loads which may result in heat stress or

distress due to personal protective equipment (powered, positive flow, full face apparatus may be an option).

Published occupational exposure limits, where they exist, will assist in determining the adequacy of the selected respiratory protection. These may be

government mandated or vendor recommended.

Certified respirators will be useful for protecting workers from inhalation of particulates when properly selected and fit tested as part of a complete

respiratory protection program.

Use approved positive flow mask if significant quantities of dust becomes airborne.

Try to avoid creating dust conditions.

SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Appearance

Beige free flowing micro-granulate; does not mix with water.

Physical state

Divided Solid

Relative density

(Water = 1)

Not Available

Odour

Not Available

Partition coefficient

n-octanol / water

Not Available

Odour threshold

Not Available

Auto-ignition

temperature (°C)

Not Applicable

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pH (as supplied)

Not Applicable

Decomposition

temperature

Not Available

Melting point /

freezing point (°C)

Not Available

Viscosity (cSt)

Not Available

Initial boiling point

and boiling range (°C)

Not Applicable

Molecular weight

(g/mol)

Not Applicable

Flash point (°C)

Not Applicable

Taste

Not Available

Evaporation rate

Not Applicable

Explosive properties

Not Available

Flammability

Not Applicable

Oxidising properties

Not Available

Upper Explosive Limit

(%)

Not Applicable

Surface Tension

(dyn/cm or mN/m)

Not Applicable

Lower Explosive Limit

(%)

Not Applicable

Volatile Component

(%vol)

Not Available

Vapour pressure (kPa)

Not Available

Gas group

Not Available

Solubility in water

(g/L)

Immiscible

pH as a solution (1%)

Not Applicable

Vapour density (Air =

1)

Not Applicable

VOC g/L

Not Available

SECTION 10 STABILITY AND REACTIVITY

Reactivity

See section 7

Chemical stability

Unstable in the presence of incompatible materials.

Product is considered stable.

Hazardous polymerisation will not occur.

Possibility of

hazardous reactions

See section 7

Conditions to avoid

See section 7

Incompatible materials

See section 7

Hazardous

decomposition

products

See section 5

SECTION 11 TOXICOLOGICAL INFORMATION

Information on toxicological effects

Inhaled

The material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung

damage.

Inhalation of dusts, generated by the material during the course of normal handling, may be damaging to the health of the

individual.

Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may

incur further disability if excessive concentrations of particulate are inhaled.

If prior damage to the circulatory or nervous systems has occurred or if kidney damage has been sustained, proper

screenings should be conducted on individuals who may be exposed to further risk if handling and use of the material result

in excessive exposures.

Ingestion

Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may

be fatal or may produce serious damage to the health of the individual.

Ionophores are common antibacterials. Toxic levels can cause cell death and may result when high amounts are taken

through food, from exposure to undiluted formulations or from mixing errors. They may be potentiated by various antibiotics

incorporated into feeds. Side effects may include muscle damage, loss of appetite, heart failure, difficulty in breathing,

watery stools, muscle stiffness and weakness.

Skin Contact

The material may cause moderate inflammation of the skin either following direct contact or after a delay of some time.

Repeated exposure can cause contact dermatitis which is characterised by redness, swelling and blistering.

Repeated exposure may cause skin cracking, flaking or drying following normal handling and use.

Open cuts, abraded or irritated skin should not be exposed to this material

Eye

If applied to the eyes, this material causes severe eye damage.

Chronic

Long-term exposure to respiratory irritants may result in disease of the airways involving difficult breathing and related

systemic problems.

Prolonged or repeated skin contact may cause drying with cracking, irritation and possible dermatitis following.

Substance accumulation, in the human body, may occur and may cause some concern following repeated or long-term

occupational exposure.

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Legend:

– Data available but does not fill the criteria for classification

– Data required to make classification available

– Data Not Available to make classification

Pure calcium carbonate does not cause the disease pneumoconiosis probably due to its rapid elimination from the body.

However, its unsterilised particulates can infect the lung and airway to cause inflammation.

Long term exposure to high dust concentrations may cause changes in lung function i.e. pneumoconiosis, caused by

particles less than 0.5 micron penetrating and remaining in the lung.

Saleco 120 Granular

TOXICITY

IRRITATION

Not Available

Not Available

calcium carbonate

TOXICITY

IRRITATION

dermal (rat) LD50: >2000 mg/kg

Eye (rabbit): 0.75 mg/24h - SEVERE

Oral (rat) LD50: >2000 mg/kg

Skin (rabbit): 500 mg/24h-moderate

salinomycin

monosodium salt

TOXICITY

IRRITATION

Not Available

Not Available

Legend:

1. Value obtained from Europe ECHA Registered Substances - Acute toxicity 2.* Value obtained from manufacturer's SDS.

Unless otherwise specified data extracted from RTECS - Register of Toxic Effect of chemical Substances

CALCIUM CARBONATE

No evidence of carcinogenic properties. No evidence of mutagenic or teratogenic effects.

SALINOMYCIN

MONOSODIUM SALT

The clinical signs and pathology in an outbreak of toxicity in feedlot cattle attributed to the ingestion of toxic levels of the

ionophore antibiotic salinomycin over an extended period of 11 weeks are described. Thirty-nine out of 380 cattle developed

signs consistent with cardiac failure and 8 of these died. Clinical signs included dyspnoea, tachypnoea, tachycardia and

exercise intolerance. Two cattle were necropsied and in one there were macroscopic lesions suggestive of congestive heart

failure, namely pulmonary oedema, hydrothorax and hepatomegaly.

Saleco 120 Granular &

CALCIUM CARBONATE

Asthma-like symptoms may continue for months or even years after exposure to the material ceases. This may be due to a

non-allergenic condition known as reactive airways dysfunction syndrome (RADS) which can occur following exposure to high

levels of highly irritating compound. Key criteria for the diagnosis of RADS include the absence of preceding respiratory

disease, in a non-atopic individual, with abrupt onset of persistent asthma-like symptoms within minutes to hours of a

documented exposure to the irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to severe

bronchial hyperreactivity on methacholine challenge testing and the lack of minimal lymphocytic inflammation, without

eosinophilia, have also been included in the criteria for diagnosis of RADS.

Saleco 120 Granular &

SALINOMYCIN

MONOSODIUM SALT

No significant acute toxicological data identified in literature search.

Saleco 120 Granular &

CALCIUM CARBONATE

The material may produce severe irritation to the eye causing pronounced inflammation. Repeated or prolonged exposure to

irritants may produce conjunctivitis.

Saleco 120 Granular &

CALCIUM CARBONATE

The material may cause skin irritation after prolonged or repeated exposure and may produce on contact skin redness,

swelling, the production of vesicles, scaling and thickening of the skin.

Acute Toxicity

Carcinogenicity

Skin

Irritation/Corrosion

Reproductivity

Serious Eye

Damage/Irritation

STOT - Single

Exposure

Respiratory or Skin

sensitisation

STOT - Repeated

Exposure

Mutagenicity

Aspiration Hazard

SECTION 12 ECOLOGICAL INFORMATION

Toxicity

Ingredient

Endpoint

Test Duration (hr)

Species

Value

Source

calcium carbonate

LC50

Fish

>56000mg/L

calcium carbonate

EC50

Algae or other aquatic plants

>14mg/L

calcium carbonate

NOEC

Algae or other aquatic plants

14mg/L

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Legend:

Extracted from 1. IUCLID Toxicity Data 2. Europe ECHA Registered Substances - Ecotoxicological Information - Aquatic Toxicity

3. EPIWIN Suite V3.12 - Aquatic Toxicity Data (Estimated) 4. US EPA, Ecotox database - Aquatic Toxicity Data 5. ECETOC

Aquatic Hazard Assessment Data 6. NITE (Japan) - Bioconcentration Data 7. METI (Japan) - Bioconcentration Data 8. Vendor

Data

DO NOT discharge into sewer or waterways.

Persistence and degradability

Ingredient

Persistence: Water/Soil

Persistence: Air

No Data available for all ingredients

No Data available for all ingredients

Bioaccumulative potential

Ingredient

Bioaccumulation

No Data available for all ingredients

Mobility in soil

Ingredient

Mobility

No Data available for all ingredients

SECTION 13 DISPOSAL CONSIDERATIONS

Waste treatment methods

Product / Packaging

disposal

Containers may still present a chemical hazard/ danger when empty.

Return to supplier for reuse/ recycling if possible.

Otherwise:

If container can not be cleaned sufficiently well to ensure that residuals do not remain or if the container cannot be used to

store the same product, then puncture containers, to prevent re-use, and bury at an authorised landfill.

Where possible retain label warnings and SDS and observe all notices pertaining to the product.

Legislation addressing waste disposal requirements may differ by country, state and/ or territory. Each user must refer to

laws operating in their area. In some areas, certain wastes must be tracked.

A Hierarchy of Controls seems to be common - the user should investigate:

Reduction

Reuse

Recycling

Disposal (if all else fails)

This material may be recycled if unused, or if it has not been contaminated so as to make it unsuitable for its intended use.

DO NOT allow wash water from cleaning or process equipment to enter drains.

It may be necessary to collect all wash water for treatment before disposal.

In all cases disposal to sewer may be subject to local laws and regulations and these should be considered first.

Where in doubt contact the responsible authority.

SECTION 14 TRANSPORT INFORMATION

Labels Required

Marine Pollutant

HAZCHEM

Not Applicable

Land transport (ADG): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

Air transport (ICAO-IATA / DGR): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

Sea transport (IMDG-Code / GGVSee): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

Transport in bulk according to Annex II of MARPOL and the IBC code

Not Applicable

SECTION 15 REGULATORY INFORMATION

Safety, health and environmental regulations / legislation specific for the substance or mixture

CALCIUM CARBONATE(471-34-1) IS FOUND ON THE FOLLOWING REGULATORY LISTS

Chemwatch: 4856-62

Version No: 3.1.1.1

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Issue Date: 16/07/2016

Print Date: 25/10/2016

Continued...

Australia Exposure Standards

Australia Inventory of Chemical Substances (AICS)

SALINOMYCIN MONOSODIUM SALT(55721-31-8) IS FOUND ON THE FOLLOWING REGULATORY LISTS

Not Applicable

National Inventory

Status

Australia - AICS

N (salinomycin monosodium salt)

Canada - DSL

Canada - NDSL

N (salinomycin monosodium salt)

China - IECSC

N (salinomycin monosodium salt)

Europe - EINEC /

ELINCS / NLP

N (salinomycin monosodium salt)

Japan - ENCS

N (salinomycin monosodium salt)

Korea - KECI

N (salinomycin monosodium salt)

New Zealand - NZIoC

Philippines - PICCS

N (salinomycin monosodium salt)

USA - TSCA

N (salinomycin monosodium salt)

Legend:

Y = All ingredients are on the inventory

N = Not determined or one or more ingredients are not on the inventory and are not exempt from listing(see specific ingredients

in brackets)

SECTION 16 OTHER INFORMATION

Other information

Ingredients with multiple cas numbers

Name

CAS No

calcium carbonate

471-34-1, 13397-26-7, 15634-14-7, 1317-65-3, 72608-12-9, 878759-26-3, 63660-97-9, 459411-10-0, 198352-33-9, 146358-95-4

Classification of the preparation and its individual components has drawn on official and authoritative sources as well as independent review by the

Chemwatch Classification committee using available literature references.

A list of reference resources used to assist the committee may be found at:

www.chemwatch.net

The SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are

Risks in the workplace or other settings. Risks may be determined by reference to Exposures Scenarios. Scale of use, frequency of use and current or

available engineering controls must be considered.

Definitions and abbreviations

TWA: Permissible Concentration-Time Weighted Average

STEL: Permissible Concentration-Short Term Exposure Limit

IARC: International Agency for Research on Cancer

ACGIH: American Conference of Governmental Industrial Hygienists

STEL: Short Term Exposure Limit

TEEL: Temporary Emergency Exposure Limit

IDLH: Immediately Dangerous to Life or Health Concentrations

OSF: Odour Safety Factor

NOAEL :No Observed Adverse Effect Level

LOAEL: Lowest Observed Adverse Effect Level

TLV: Threshold Limit Value

LOD: Limit Of Detection

OTV: Odour Threshold Value

BCF: BioConcentration Factors

BEI: Biological Exposure Index

Chemwatch: 4856-62

Version No: 3.1.1.1

Page 10 of 10

Saleco 120 Granular

Issue Date: 16/07/2016

Print Date: 25/10/2016

end of SDS

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