Rifadin 300mg capsules

Country: United Kingdom

Language: English

Source: MHRA (Medicines & Healthcare Products Regulatory Agency)

Active ingredient:

Rifampicin

Available from:

Sigma Pharmaceuticals Plc

ATC code:

J04AB02

INN (International Name):

Rifampicin

Dosage:

300mg

Pharmaceutical form:

Oral capsule

Administration route:

Oral

Class:

No Controlled Drug Status

Prescription type:

Valid as a prescribable product

Product summary:

BNF: 05010900

Patient Information leaflet

RIFADIN 300MG CAPSULES
rifampicin
PACKAGE LEAFLET:
INFORMATION FOR THE USER
IN PARTICULAR, DO NOT TAKE THIS MEDICINE, AND TELL YOUR DOCTOR, IF YOU
ARE TAKING:
•
Saquinavir or ritonavir used for HIV infection
THE FOLLOWING MEDICINES CAN MAKE RIFADIN 300MG CAPSULES WORK LESS
WELL:
•
Antacids used for indigestion. Take Rifadin 300mg Capsules at least 1
hour before
taking antacids
•
Other medicines used for TB such as P-aminosalicyclic acid (PAS). PAS
and Rifadin
300mg Capsules should be taken at least 8 hours apart
TELL YOUR DOCTOR IF YOU
ARE TAKING ANY OF THE FOLLOWING MEDICINES:
HEART AND BLOOD MEDICINES
•
Medicines for high blood pressure
•
Medicines for heart problems or to control your heartbeat
•
Medicines used to thin the blood such as warfarin
•
Medicines used to lower cholesterol
•
Water tablets (diuretics) such as eplerenone
MENTAL HEALTH, EPILEPSY AND MOTOR NEURONE MEDICINES
•
Medicines for thought disorders known as ‘antipsychotics’ such as
haloperidol
•
Medicines to calm or reduce anxiety (hypnotics, anxiolytics)
•
Medicines to help you sleep (barbiturates)
•
Medicines used for epilepsy such as phenytoin
•
Some medicines used for depression such as amitriptyline and
nortriptyline
•
Riluzole - used for motor neurone disease
MEDICINES FOR INFECTIONS AND THE IMMUNE SYSTEM
•
Some medicines used for viral infections such as indinavir, efavirenz,
amprenavir,
nelfinavir, atazanavir, lopinavir, neviparine, daclatasvir,
simeprevir, sofosbuvir and
telaprevir
•
Medicines used for fungal infections
•
Medicines used for bacterial infections (antibiotics)
• Medicines used for lowering your immune system such as
ciclosporin, sirolimus
and tacrolimus
•
Praziquantel - used for tapeworm infections
•
Atovaquone - used for pneumonia
HORMONE AND CANCER MEDICINES
• Some hormone medicines (estrogen, systemic hormones, progestogens)
used for
contraception or some types of cancer such as ethinyloestradiol,
levonorgestrel or
dydrogesterone
•
Some hormone medicines (anti-estrogens)

Summary of Product characteristics

SUMMARY OF PRODUCT CHARACTERISTICS
1
NAME OF THE MEDICINAL PRODUCT
Rifadin 300mg Capsules
2
QUALITATIVE AND QUANTITATIVE COMPOSITION
Rifampicin Ph Eur 300 mg
For a full list of excipients, see section 6.1.
3
PHARMACEUTICAL FORM
Capsule, hard.
The gelatin capsule is opaque, composed of a scarlet body and cap,
marked R-300.
4.1
THERAPEUTIC INDICATIONS
Indications for use
Tuberculosis: In combination with other active anti-tuberculosis drugs
in the
treatment of all forms of tuberculosis, including fresh, advanced,
chronic and
drug-resistant cases. Rifadin is also effective against most atypical
strains of
Mycobacteria.
Leprosy: In combination with at least one other active anti-leprosy
drug in the
management of multibacillary and paucibacillary leprosy to effect
conversion
of the infectious state to a non-infectious state.
Other Infections: In the treatment of Brucellosis, Legionnaires
Disease, and
serious staphylococcal infections. To prevent emergence of resistant
strains of
the infecting organisms, Rifadin should be used in combination with
another
antibiotic appropriate for the infection.
Prophylaxis of meningococcal meningitis: For the treatment of
asymptomatic
carriers of N. meningitidis to eliminate meningococci from the
nasopharynx.
Haemophilus influenzae: For the treatment of asymptomatic carriers of
H.influenzae and as chemoprophylaxis of exposed children, 4 years of
age or
younger.
4.2
POSOLOGY AND METHOD OF ADMINISTRATION
Recommended Dosage
For oral administration
The daily dose of Rifadin, calculated from the patient’s body
weight, should
preferably be taken at least 30 minutes before a meal or 2 hours after
a meal to ensure
rapid and complete absorption.
Tuberculosis:
Rifadin should be given with other effective anti-tuberculosis drugs
to prevent the
possible emergence of rifampicin-resistant strains of Mycobacteria.
_Adults_: The recommended single daily dose in tuberculosis is 8-12
mg/kg.
_Usual Daily dose_: Patients weighing less than 50 kg - 450 mg.
Patients weighing 50
kg or more – 600 mg.
_Ch