REVOLUTION- selamectin solution

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

SELAMECTIN (UNII: A2669OWX9N) (SELAMECTIN - UNII:A2669OWX9N)

Available from:

Zoetis Inc.

INN (International Name):

SELAMECTIN

Composition:

SELAMECTIN 60 mg in 1 mL

Administration route:

TOPICAL

Prescription type:

PRESCRIPTION

Therapeutic indications:

Revolution is recommended for use in dogs six weeks of age or older and cats eight weeks of age and older for the following parasites and indications: Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis ), prevention of heartworm disease caused by Dirofilaria immitis , and the treatment and control of ear mite (Otodectes cynotis ) infestations. Revolution also is indicated for the treatment and control of sarcoptic mange (Sarcoptes scabiei ) and for the control of tick infestations due to Dermacentor variabilis . Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis ), prevention of heartworm disease caused by Dirofilaria immitis , and the treatment and control of ear mite (Otodectes cynotis ) infestations. Revolution is also indicated for the treatment and control of roundworm (Toxocara cati ) and intestinal hookworm (Ancylostoma tubaeforme ) infections in cats.

Product summary:

Available in eight separate dose strengths for dogs and cats of different weights (see DOSAGE).  Revolution for puppies and kittens is available in cartons containing 3 single dose tubes. Revolution for cats and dogs is available in cartons containing 3 or 6 single dose tubes.

Authorization status:

New Animal Drug Application

Summary of Product characteristics

REVOLUTION- SELAMECTIN SOLUTION
ZOETIS INC.
----------
REVOLUTION (SELAMECTIN)
REVOLUTION® (selamectin)
Topical Parasiticide For Dogs and Cats
CAUTION
US Federal law restricts this drug to use by or on the order of a
licensed veterinarian.
DESCRIPTION
Revolution (selamectin) Topical Parasiticide is available as a
colorless to yellow, ready to
use solution in single dose tubes for topical (dermal) treatment of
dogs six weeks of age
and older and cats eight weeks of age and older. The content of each
tube is formulated
to provide a minimum of 2.7 mg/lb (6 mg/kg) of body weight of
selamectin. The chemical
composition of selamectin is
(5Z,25S)-25-cyclohexyl-4'-_O-_de(2,6-dideoxy-3-_O-_methyl-α-
L-_arabino_-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-
hydroxyiminoavermectin A
.
INDICATIONS
Revolution is recommended for use in dogs six weeks of age or older
and cats eight
weeks of age and older for the following parasites and indications:
DOGS:
Revolution kills adult fleas and prevents flea eggs from hatching for
one month and is
indicated for the prevention and control of flea infestations
(_Ctenocephalides felis_),
prevention of heartworm disease caused by_ Dirofilaria immitis_, and
the treatment and
control of ear mite (_Otodectes cynotis_) infestations. Revolution
also is indicated for the
treatment and control of sarcoptic mange (_Sarcoptes scabiei_) and for
the control of tick
infestations due to _Dermacentor variabilis_.
CATS:
Revolution kills adult fleas and prevents flea eggs from hatching for
one month and is
indicated for the prevention and control of flea infestations
(_Ctenocephalides felis_),
prevention of heartworm disease caused by D_irofilaria immitis_, and
the treatment and
control of ear mite (_Otodectes cynotis_) infestations. Revolution is
also indicated for the
treatment and control of roundworm (_Toxocara cati_) and intestinal
hookworm
(_Ancylostoma tubaeforme_) infections in cats.
DOSAGE AND ADMINISTRATION
®
1a
The recommended minimum dose is 2.7 mg selamectin per pound (