QUPRON TABLETS 250 mg

Country: Singapore

Language: English

Source: HSA (Health Sciences Authority)

Active ingredient:

CIPROFLOXACIN HCl EQV CIPROFLOXACIN

Available from:

ZYFAS PHARMA PTE LTD

ATC code:

J01MA02

Dosage:

250 mg

Pharmaceutical form:

TABLET, FILM COATED

Composition:

CIPROFLOXACIN HCl EQV CIPROFLOXACIN 250 mg

Administration route:

ORAL

Prescription type:

Prescription Only

Manufactured by:

SHIN POONG PHARMACEUTICAL CO LTD

Authorization status:

ACTIVE

Authorization date:

1997-12-05

Summary of Product characteristics

QUPRON
Tablets
Ciprofloxacin HCl
Bactericidal Antibacterial Agents
250mg
500mg
【COMPOSITION】
Each tablet contains
Ciprofloxacin HCl
…………………………………………………………………………………………………………………………………………
291.0mg or 582.0mg
(As 250mg (potency) or 500mg (potency) of Ciprofloxacin)
【INDICATIONS】
1.
Susceptible organisms : E. coli, Shigella, Salmonella, Citrobacter,
Klebsiella, Enterobacter, Serratia, hafnia, proteus(Indole positive &
negative). Pseudomo-
nas, Neisseria, Acinetobacter, Streptococcus, Chlamydia,
Staphylococcus,Corynebacterium, Bacteroides, Clostridium
2. Indications
Respiratory infections, infections of oral cavity, teeth and jaw,
infections of ear, nose and throat, infections of kidney or urinary
passages, genital infec-
tions containing gonorrhea, gastrointestinal infections, infection and
wound of soft tissue, infections of bone and joint, infections in
gynecological and
obstetric field, septicemia, cerebromeningitis, peritonitis,
ophthalmologic infections and infections in bile secretory duct.
【DOSAGE AND ADMINISTRATION】
1.
Usually for adults, administer 250~500mg at meal intervals twice a
day. In severe mixed infections, administer up to750mg twice a day. In
acute infec-
tions, usually treat for 5 to 10 days. After disappearance of
symptoms, furtheradministration is required at least for 3 days.
2. In patients with severe renal disorder, it should be administered
according to the following dosage and administration.
When only the concentration of serum creatinine clearance is known,
the patient's creatinine clearance can be estimated by using the
following for-
mulas:
In patient with severe cardiac failure and infections, 750mg can be
administered once, but careful monitoring is required and the
ciprofloxacin concentra-
tion should be periodically estimated. At that time, the peak serum
concentration (obtained 1~2 hours after administration) should range
from 2~4μg/ml.
3. Dosage may be adjusted accor