PROPOVAN- propofol injection, emulsion

Country: United States

Language: English

Source: NLM (National Library of Medicine)

Active ingredient:

PROPOFOL (UNII: YI7VU623SF) (PROPOFOL - UNII:YI7VU623SF)

Available from:

MWI/VetOne

INN (International Name):

PROPOFOL

Composition:

PROPOFOL 10 mg in 1 mL

Administration route:

INTRAVENOUS

Prescription type:

PRESCRIPTION

Therapeutic indications:

VetOne® Propovan™ CF (propofol) is an anesthetic injection for use in dogs and cats as follows: 1. As a single injection to provide general anesthesia for short procedures. 2. For induction and maintenance of general anesthesia using incremental doses to effect. 3. For induction of general anesthesia where maintenance is provided by inhalant anesthetics. Induction of general anesthesia will usually be observed within 30 to 60 seconds after the end of administration (administration should take 60 to 90 seconds). The doses for induction and maintenance vary depending upon species and preanesthetics. The duration of anesthesia varies depending upon species, dose, and preanesthetics. In dogs, the duration of anesthesia following the recommended induction dose (5.5 to 7.0 mg/kg without premedication) is generally 5 to 7 minutes. The duration of anesthesia after maintenance doses varies from 2 to 6 minutes following 1.1 mg/kg to 6 to 10 minutes following 3.3 mg/kg. Full standing recovery is generally observed with

Product summary:

VetOne® Propovan™ CF injection is supplied in cartons of five-20 mL vials containing 10 mg propofol per mL.

Authorization status:

New Animal Drug Application

Summary of Product characteristics

PROPOVAN- PROPOFOL INJECTION, EMULSION
MWI/VETONE
----------
VETONE PROPOVAN™ CF
For Animals Only
VETONE
PROPOVAN™ CF
(PROPOFOL INJECTABLE EMULSION)
ANESTHETIC INJECTION
Each mL contains 10 mg propofol
NADA 141-070
Emulsion for intravenous use in dogs and cats.
CAUTION: Federal law restricts this drug to use by or on the order of
a licensed veterinarian.
DESCRIPTION
VetOne
Propovan™ CF (propofol) injection is a sterile, nonpyrogenic
emulsion containing 10 mg/mL
of propofol suitable for intravenous administration. Propofol is
chemically described as 2,6-
diisopropylphenol and has a molecular weight of 178.28. Propofol is
very slightly soluble in water and
is therefore formulated as a white, oil-in-water emulsion. Each mL
contains propofol (10 mg), soybean
oil (100 mg), glycerol (22.5 mg), egg yolk phospholipid (12 mg) and
sodium metabisulfite (0.25 mg),
with sodium hydroxide to adjust the pH. The propofol emulsion is
isotonic and has a pH of 4.5-6.6.
INDICATIONS
VetOne
Propovan™ CF (propofol) is an anesthetic injection for use in dogs
and cats as follows:
1. As a single injection to provide general anesthesia for short
procedures.
2. For induction and maintenance of general anesthesia using
incremental doses to effect.
3. For induction of general anesthesia where maintenance is provided
by inhalant anesthetics.
Induction of general anesthesia will usually be observed within 30 to
60 seconds after the end of
administration (administration should take 60 to 90 seconds). The
doses for induction and maintenance
vary depending upon species and preanesthetics. The duration of
anesthesia varies depending upon
species, dose, and preanesthetics.
In dogs, the duration of anesthesia following the recommended
induction dose (5.5 to 7.0 mg/kg without
premedication) is generally 5 to 7 minutes. The duration of anesthesia
after maintenance doses varies
from 2 to 6 minutes following 1.1 mg/kg to 6 to 10 minutes following
3.3 mg/kg. Full standing recovery
is generally observed within 10 to 20 minutes after the end of
anest