PRIZMA

118778010

07B19

PATIENT PACKAGE INSERT IN ACCORDANCE

WITH THE PHARMACISTS’ REGULATIONS

)PREPARATIONS( - 1986

The medicine is dispensed with

a doctor’s prescription only

Prizma/ Prizma Forte

Tablets

Composition:

Each Prizma tablet contains:

Fluoxetine )as HCl( 20 mg

Each Prizma Forte tablet contains:

Fluoxetine )as HCl( 60 mg

Read the leaflet carefully in its entirety before using

the medicine. This leaflet contains concise information

about the medicine. If you have further questions, refer

to the doctor or pharmacist.

This medicine has been prescribed for the treatment

of your ailment. Do not pass it on to others. It may

harm them even if it seems to you that their medical

condition is similar.

Antidepressants and anti-anxiety medicines

increase the risk for suicidal behavior and thoughts

in children, adolescents and young adults up to the

age of 25.

When starting treatment with the medicine, patients

of all ages and their relatives must monitor for

behavioral changes, such as: worsened depression,

suicidal thoughts, aggressiveness and the like.

If such changes occur, refer to a doctor immediately.

This medicine is not intended for use in children.

1.

WHAT IS THE MEDICINE INTENDED FOR?

Prizma/ Prizma Forte is intended to treat:

depression

obsessive compulsive disorder )OCD(

bulimia nervosa

Therapeutic group: Prizma/ Prizma Forte belongs to

the selective serotonin reuptake inhibitor )SSRIs( group.

2.

BEFORE USING THE MEDICINE

Do not use the medicine if:

You are sensitive )allergic( to fluoxetine or to any of

the inactive ingredients contained in the medicine

)see section 6: "Further Information"(.

Do not use this medicine concomitantly with the

antipsychotic medicine pimozide.

Do not use this medicine concomitantly with

monoamine-oxidase inhibitor )MAOI( type

antidepressants )e.g., methylene blue and the

linezolid antibiotics( or with thioridazine for

treatment of schizophrenia. Wait 14 days from

completing treatment with monoamine-oxidase

inhibitors )MAOI( before beginning treatment with

this medicine.

Do not start treatment with

monoamine-oxidase

inhibitor

-type antidepressants or with thioridazine

if at least 5 weeks have not elapsed from the time of

discontinuing treatment with Prizma/ Prizma Forte.

Do not use this medicine when you are pregnant

or breastfeeding, unless you have consulted

your doctor and have discussed with him the

risk versus benefit of taking this medicine, as

use of medicines that belong to this group

)antidepressants( may affect the general

condition of your baby.

Special warnings regarding use of this medicine:

!

Suicidal thoughts and worsened depression:

Depression and additional severe psychiatric

disorders are known to be the highest risk factors

for suicide.

It is advisable that you inform a family member or

close friend that you are suffering from depression,

and ask them to monitor for mood and behavior

changes, such as: worsening of depression and/or

onset of suicidal thoughts, a new or sudden change

in behavior, thoughts or feelings – particularly a

severe change, restlessness, aggressiveness or

sleep disturbances. If you experience such changes,

refer to a doctor immediately. Pay particular

attention to these changes at the beginning of

treatment or when the dosage is changed.

The following symptoms have been reported

in adults, children and adolescents treated

with antidepressants: anxiety, restlessness,

panic attacks, lack of sleep, irritability, hostility,

aggressiveness, impulsiveness, mania.

Prizma/ Prizma Forte and other antidepressants

can increase suicidal thoughts or actions

and hostility in some children, adolescents

or young adults during the first months of

treatment or when the dosage is changed. This

recommendation should be particularly followed

if you are 18-24 years of age. Nevertheless, your

doctor can prescribe this medicine for you if he

thinks it will be beneficial for you. If the doctor

prescribed this medicine for you and you are

interested in discussing it with him - refer back to

the doctor. You must report to your doctor if some

of the above-mentioned side effects have appeared

or worsened.

Switch from a lying down or sitting position to

standing gradually, to avoid feeling dizzy.

Use this medicine with caution in patients with a

history of mania.

If you are being treated with this preparation and are

planning a pregnancy or are pregnant, do not stop

treatment on your own, rather, consult the doctor.

While taking antidepressants from the SSRI )such

as Prizma/ Prizma Forte( and SNRI groups,

you may experience serotonin syndrome )rare(

which includes symptoms such as nervousness,

confusion, sweating, hyperreflexia, muscle spasms,

tremors and increased heart rate, high fever. This

syndrome may occur more frequently if you are

concomitantly taking other medicines that affect

the central nervous system )see section “Drug

interactions”(. If you experience these symptoms,

refer to a doctor immediately.

Inform the doctor about any additional medicine that

you are taking.

There are no data on the long-term effects from

a safety standpoint in relation to growth and

development, maturation, cognitive behavior and

behavioral development in children and adolescents.

If you are diabetic, consult your doctor whether a

dosage adjustment of your diabetes medicines is

necessary, since a decrease in blood sugar levels

may occur when taking Prizma/ Prizma Forte.

When using the medicine, you may experience

cardiac arrhythmias )QT interval prolongation and

irregular heart rate, Torsades de Pointes(. This

condition may be life-threatening. You must refer to

your doctor immediately.

Inform your doctor if you suffer from congenital

cardiac arrhythmia )QT interval prolongation(, if

you have a history of QT prolongation or if you or

someone in your family has a history of cardiac

arrhythmias. In addition, tell your doctor if anyone

in your family died suddenly.

The following conditions can increase the risk

of cardiac arrhythmias: use of medicines that

prolong the QT interval, low levels of potassium

or magnesium in the blood, a recent heart attack,

uncompensated

heart

failure,

arrhythmias,

concomitant use of medicines that affect the cardiac

activity and situations where the level of medicine

increases such as: overdose, hepatic impairment

and medicines that affect the level of Prizma/

Prizma Forte )see section "Drug interactions"(.

Angle-Closure Glaucoma - the pupillary dilation

that sometimes occurs following frequent use of

antidepressant medicines such as Prizma/ Prizma

Forte, may trigger an angle closure glaucoma attack

in patients with anatomically narrow angles who

have not undergone iridectomy.

If allergic side effects or a rash develops, refer to a

doctor.

Bleeding - concomitant use of medicines from the

SSRI/SNRI group medicines in combination with

aspirin, NSAIDs, anti-inflammatories, warfarin and

other anti-coagulant medicines - increases the risk

of bleeding in the digestive system.

Low levels of sodium in the blood have been

reported while using SSRI/SNRI medicines

)especially in elderly patients(. If you are taking

diuretics or have experienced signs of low sodium

levels )headache, difficulty concentrating, memory

impairment, confusion, hallucinations, weakness

and unsteadiness that may lead to falls - inform your

doctor(.

There is no data regarding the long-term effects

from a safety standpoint in relation to growth and

development, maturation, cognitive behavior and

behavioral development in children and adolescents.

Do not give this medication to children.

!

Before treatment with Prizma/ Prizma Forte, tell

the doctor if:

You are sensitive to any kind of food or medicine.

You have high blood pressure.

You are pregnant or are trying to become pregnant.

Speak to your doctor about the benefits and risks

of treating depression while pregnant.

You are taking prescription medicines, over-

the-counter medicines, vitamins and nutritional

supplements. Some of the medicines may cause an

interaction with one another, will not work properly

or cause serious side effects.

You suffer or have suffered in the past from

unexplained bleeding, bruises or wounds.

You suffer or have suffered in the past from epilepsy

or seizures. If you experience a seizure attack or

there is an increase in the frequency of seizures,

refer to a doctor immediately, you may need to

discontinue treatment with this medicine.

You suffer or have suffered in the past from a bipolar

or manic episode. Refer to a doctor immediately,

there may be a need to discontinue treatment with

this medicine.

You suffer or have suffered in the past from heart

problems or changes in electrical activity of the heart

)QT interval prolongation or arrhythmias(.

You are taking medicines that affect the cardiac

activity/prolong the QT interval.

You are taking anti-inflammatory/anti-coagulant

medicines.

You suffer or have suffered in the past from low

sodium levels.

You have had a stroke.

You suffer or have suffered in the past from increased

intraocular pressure, angle closure glaucoma or eye

problems such as: eye pain, vision changes, swelling

or redness around the eye.

You suffer or have suffered in the past from hepatic

impairment.

You suffer or have suffered in the past from impaired

function of the kidneys.

You have diabetes. It is possible that the doctor will

need to adjust the dosage of insulin or medicines

that you are taking.

You are taking medicines that affect the central

nervous system )serotonin syndrome(.

You are undergoing electroconvulsive therapy )ECT(.

!

Drug interactions:

If you are taking other medicines, including

nonprescription medicines and nutritional

supplements, tell the doctor or pharmacist. In

particular, inform the doctor or pharmacist if you are

taking:

Do not use Prizma/ Prizma Forte concomitantly

with the antipsychotic medicine pimozide.

Do not use this medicine concomitantly with

thioridazine for the treatment of schizophrenia.

Additional medicines that affect the central

nervous system )such as: tranquilizers ]diazepam[,

hypnotics, medicines for Parkinson's disease and

epilepsy(.

Monoamine oxidase inhibitors )MAOI( )such as:

methylene blue and the antibiotic linezolid( – do

not use concomitantly with Prizma/ Prizma Forte

or within 14 days from cessation of treatment with

a medicine from the MAOI group. Wait at least 5

weeks following cessation of treatment with Prizma/

Prizma Forte before starting treatment with a MAOI

)see section "Do not use this medicine if"(.

Metoprolol for the treatment of heart failure – there

is an increased risk of experiencing side effects of

metoprolol, including slow heart rate )bradycardia(

due to increased medicine concentration when

given with Prizma/ Prizma Forte.

Before beginning treatment with Prizma/ Prizma

Forte, tell your doctor if you are taking the following

medications or treatments:

Triptans intended to treat a migraine )headache(

Medicines used to treat mood, anxiety, psychotic

disturbances or thought disorders, including

tricyclics,

lithium,

buspirone,

SSRI,

SNRI,

antipsychotics.

Amphetamines.

Tramadol or fentanyl.

Tryptophan )an amino acid found in food, nutrition

infusion solutions and nutritional supplements( or

St. John's Wort )Hypericum for treating depression(.

Do not take Prizma/Prizma Forte concomitantly

with other medicines containing fluoxetine, which

includes: symbyax, sarafem and Prizma/Prizma

Forte weekly dosing.

Electroconvulsive therapy )ECT(.

Combining the above mentioned medicines at the

same time with Prizma/ Prizma Forte may cause

an increase in the prevalence of serotonin syndrome

)rare( )see section "Special warnings regarding use

of this medicine"(.

Medicines whose blood concentration is affected

by concomitant use with Prizma/ Prizma Forte:

Antipsychotics

)such

haloperidol,

phenothiazines

atypical

medicines

such as clozapine, ziprasidone, iloperidone,

chlorpromazine, mesoridazine, droperidol( and

other dopamine antagonists.

Pimozide – do not use concomitantly with

Prizma/ Prizma Forte due to the increased risk

of interaction of the QT interval prolongation

Tricyclic antidepressants )such as imipramine,

desipramine, amitriptyline(

Medicines for the treatment of heart rhythm

disturbances )such as: digitalis, propafenone,

flecainide, quinidine, procainamide, amiodarone,

sotalol(

Medicines

epilepsy

)phenytoin,

carbamazepine(

Sedatives and hypnotics from the benzodiazepine

group )such as diazepam and alprazolam(

Lithium

Warfarin )may increase the risk of bleeding(

Vinblastine

Antibiotics )such as: sparfloxacin, moxifloxacin,

intravenous erythromycin, gatifloxacin(

Pentamidine

Levomethadyl acetate

Methadone

Medicines for the treatment of malaria

)halofantrine, mefloquine(

Dolasetron mesylate

Probucol

Tacrolimus

Medicines that increase the risk of bleeding:

Non-steroidal anti-inflammatory medicines

)aspirin and the like(

Medicines that prevent platelet growth

Diuretics )especially in the elderly( – increased

risk of developing hyponatremia when used

concomitantly with Prizma/ Prizma Forte.

!

Taking Prizma/ Prizma Forte with food and drink:

Prizma/ Prizma Forte can be taken with or without

food.

!

Driving and drinking alcohol:

Do not drink wine or alcoholic beverages during the

course of treatment with this medicine.

!

Pregnancy and breastfeeding:

Consult a doctor or pharmacist before using medicines.

If you are being treated with this preparation and

might be pregnant or are planning a pregnancy, or

you are pregnant, do not stop treatment on your own,

rather, consult the doctor.

Do not use this medicine if you are pregnant or

breastfeeding unless you have consulted your

doctor and discussed with him the risks versus

the benefits of taking this medicine, as the use of

medicines belonging to this group )antidepressants(

may affect the general condition of your baby.

There have been reports suggesting that in babies

whose mothers took this medicine during the first

months of pregnancy there is an increased risk of

congenital heart defects. The risk increased from 1

in 100 babies in the general population to about 2

in 100 babies in mothers who were treated with this

medicine. You and your doctor may decide on a gradual

cessation of the medicine, however, depending on

your circumstances, it may be decided to continue

with treatment. Do not stop treatment on your own,

rather, consult a doctor.

When taking SSRI and SNRI medicines including

Prizma/Prizma Forte during pregnancy, particularly

in the last trimester, the risk of a serious condition in

babies called persistent pulmonary hypertension of the

newborn )PPHN( increases and may make the baby

breathe faster and appear bluish. These symptoms

usually begin during the first 24 hours after birth. If any

one of these symptoms appears in your baby, or you

are concerned about the health of your baby, refer to

your midwife and/or doctor immediately.

If you took this medicine in the last trimester of

pregnancy or before giving birth, you should be

aware that the following effects may appear in your

baby immediately after birth: respiratory distress,

cyanosis, apnea, convulsions, body temperature

instability, feeding difficulties, vomiting, hypoglycemia,

hypotonia, hypertonia, hyperreflexia, tremor, irritabilty,

agitation, constant crying, feeding difficulties )suckling(

and sleeping difficulties.

Breastfeeding - this medicine is secreted into breast

milk and can affect your baby. Consult your doctor

regarding the safest way to feed your baby while taking

Prizma/ Prizma Forte. If it is decided to continue

breastfeeding while using this medicine, your doctor

may reduce the dosage of the medicine.

Fertility - animal studies have shown that fluoxetine

may affect the quality of the sperm. Theoretically, taking

this medicine may affect fertility, but such an effect on

humans has not been observed.

!

Driving and operating machinery - Use of this

medicine may impair your alertness, judgment and

motor skills )coordination(; therefore, caution must be

exercised when driving a car, operating dangerous

machinery and when engaging in any activity which

requires alertness.

3.

HOW SHOULD YOU USE THE MEDICINE?

Always use the medicine according to the doctor's

instructions.

Check with the doctor or pharmacist if you are

uncertain.

Take the medicine at set times, as determined by the

attending doctor.

The dosage and treatment regimen will be

determined by the doctor only. The usual dosage

is generally:

Depression - The recommended dosage is 20

mg per day. Your doctor may change the dose as

needed within 3-4 weeks of starting treatment. The

dose may be gradually increased to a maximum of

80 mg per day. The dosage should be increased

under surveillance, to ensure that you receive

the lowest effective dosage. You may not feel an

improvement immediately after starting treatment

with the medicine. A few weeks from the beginning

of treatment usually elapse until there is an

improvement in the symptoms of depression.

Bulimia nervosa - The recommended dosage is 60

mg per day.

Obsessive compulsive disorder )OCD( - The

recommended dosage is 20 mg per day. The

doctor may change the dosage, if necessary, after

two weeks of treatment. The dose may be gradually

increased to a maximum of 80 mg per day. If there

is no improvement within 10 weeks, the doctor will

consider changing the treatment.

Elderly – Increase the dosage with extra caution

and the daily dosage is generally up to 40 mg. The

maximum dosage is 60 mg per day.

Liver function disorders - If you have liver function

disorders or are using other medications that might

affect Prizma/Prizma Forte, the doctor may decide

on a lower dosage or instruct you to take Prizma/

Prizma Forte once in two days.

Do not exceed the recommended dosage!

Swallow the medicine with water, a little food or drink.

If necessary, the tablet can be halved for immediate

use. There is no information regarding crushing or

chewing the tablet.

If you took an overdose, or if a child has

accidentally

swallowed

the

medicine,

immediately refer to a doctor or proceed to a

hospital emergency room and bring the package of

the medicine with you. The symptoms of overdose

include: nausea, vomiting, convulsions, breathing

disorders/pulmonary function problems and mental

status changes ranging from hyperactivity to coma,

confusion, walking problems, unresponsiveness,

nervousness, vertigo, tremor, elevated blood

pressure, impotence, seizures, sleepiness,

heart problems such as changes in heart rate -

increased or irregular heart rate and vomiting,

loss of consciousness, low blood pressure, mania,

movement disorders and hypomania and symptoms

that are similar to neuroleptic malignant syndrome

)NMS(, which include hallucinations, increased body

temperature, muscle rigidity, autonomic instability

and changes in mental status.

If you forgot to take this medicine at the

required time, take a dose as soon as you

remember, unless it is almost time for the next dose;

in this case, skip the forgotten dose and take the next

dose the following day, at the regular time, but never

take two doses together! Adhere to the treatment

regimen recommended by the doctor. Even if there

is an improvement in your health condition, do not

stop treatment with the medicine without consulting

the doctor.

Do not stop taking the medicine suddenly

without consulting the doctor, even if there is an

improvement in your health. Do not stop treatment

with the medicine without consulting the doctor or

pharmacist.

If you stop taking the medicine, withdrawal signs may

occur, including: dizziness; tingling sensation;

sleep disturbances (vivid dreams, nightmares,

inability to sleep(; feeling restless and agitated;

unusual tiredness or weakness; anxiety; nausea

or vomiting; tremor; headaches, confusion,

emotional instability and sweating. Withdrawal

symptoms after stopping this medicine are mostly

moderate and disappear within a few weeks. If

you experience withdrawal symptoms, refer to

the doctor. It is recommended to lower the dosage

of the medicine gradually, over 1-2 weeks, in

order to reduce the chance of getting withdrawal

symptoms.

Do not take medicines in the dark! Check the

label and the dose each time you take medicine.

Wear glasses if you need them.

If you have further questions regarding use of

this medicine, consult the doctor or pharmacist.

4.

SIDE EFFECTS

As with any medicine, use of Prizma/Prizma Forte

may cause side effects in some users. Do not be

alarmed by the list of side effects. You may not suffer

from any of them.

Stop the treatment and refer to the doctor or

proceed to a hospital immediately:

in case of an allergic reaction, including rash, itching,

swelling of the face, lips, tongue, eyes or breathing

difficulties, skin reddening, appearance of blisters or

skin peeling and sometimes also fever or joint pains.

if you have thoughts of harming yourself or suicide.

Refer to the doctor if:

You experience restlessness and are unable to sit

or stand still )akathisia(.

Some patients may experience serotonin syndrome

– a combination of symptoms including: fast

breathing or rapid heart beat, changes in mental

state )restlessness, confusion, hallucinations,

nervousness, sleepiness, coma(, uncontrolled

blood pressure, dizziness, flushing, increased

body temperature, excessive sweating, tremor

or strong muscle contraction/muscle stiffness,

lack of coordination, hyperreflexia, seizures and/

or gastrointestinal symptoms )nausea, vomiting,

diarrhea( )rare(.

Feeling of weakness, dizziness or confusion,

especially in the elderly and in patients being treated

with diuretics.

Extreme irritability and agitation.

Changes in the electrical activity of the heart.

Symptoms are manifested by irregular, slow, rapid

heart rate, respiratory distress, dizziness and

fainting, dizziness upon standing from a sitting or

lying down position.

Bleeding such as: nosebleeds, hemorrhages,

gastrointestinal bleeding.

Seizures )occurs infrequently(.

Manic episodes )occurs infrequently(, expressed

by a sharp increase in energy level, severe sleep

disturbances, impulsive behavior, exaggerated

happiness or restlessness, grand ideas, rapid

speech.

Hepatitis )liver inflammation( )rare(.

Prolonged and painful erection )rare(.

Low blood sodium level )rare, occurs mainly in the

elderly(, manifested by headaches, weakness or

unsteadiness, which may lead to falls, confusion,

concentration difficulties, memory problems and in

serious cases: hallucinations, fainting, seizures, loss

of consciousness, apnea and death.

Skin effects which include redness of the skin

and the appearance of blisters and severe itching

)Stevens-Johnson syndrome and toxic epidermal

necrolysis(.

Prizma/Prizma Forte can cause serious side effects,

including:

Problems controlling blood sugar levels. Patients

who have diabetes and are taking Prizma/Prizma

Forte may suffer from low blood sugar while

taking Prizma/Prizma Forte. High sugar levels

may appear when stopping treatment. Your doctor

may have to change the dosage of your diabetes

medicines when starting or discontinuing Prizma/

Prizma Forte.

Sense of anxiety or sleep disturbances.

Common side effects in patients taking Prizma/

Prizma Forte, include:

Unusual dreams

Sexual function problems

Loss of appetite, diarrhea, digestive problems,

nausea or vomiting, weakness or dry mouth

Symptoms of the flu

Fatigue

Changes in sleep pattern

Yawning

Sinus infection or sore throat

Tremor

Sweating

Feeling anxious and irritable

Hot flashes

Rash

Other side effects in children and adolescents

include:

Increased thirst

Unusual increase in muscle movement and a sense

of restlessness

Nosebleeds

Frequent urination

Heavier monthly periods

There may be a decrease in growth rate and body

weight. The height and weight of your child should

be monitored during treatment with Prizma/ Prizma

Forte.

Side effects that appear frequently:

Dry mouth

Diarrhea, constipation, weight loss

Fever and redness in the face

Headache

Sleep problems, insomnia, emotional instability,

decreased libido, difficulty or inability to experience

orgasm

Change in sense of taste

Sleepiness, lethargy

Vision problems

Reduced concentration

Joint pains

Urination problems, including frequent urination

Chills, dizziness

Strong and/or irregular heartbeat, including QT

interval prolongation

Unexplained vaginal bleeding

Side effects that appear infrequently:

Physical restlessness )akathisia(, uncoordinated

movements )ataxia(, involuntary movements

Dilated pupils

Heart rate disturbances, hypotension

Swallowing disturbance, inflammation in the

digestive system, black stool, stomach ulcer

Small hemorrhages similar to a rash )purpura(

Balance disorder, teeth grinding, increase in libido,

depersonalization disorder, a sense of extreme

happiness, increased muscle tone, paranoid

reaction

Hair loss

Pain or burning upon urination

Suicide attempt

Tinnitus in the ears

Side effects that appear rarely:

Panic attacks, spasms, blood vessel inflammation,

rapid swelling of the neck, face, mouth and/or

throat; pain in the esophagus, sensitivity to sunlight,

hyperprolactinemia

Increased risk of bleeding

Gastrointestinal bleeding )symptoms include bloody

diarrhea, vomiting of blood(, ulcers in the digestive

tract )such as intestinal ulcer, esophageal ulcer,

peptic ulcer, gastric ulcer bleeding(

Throat edema

Side effects that appear very rarely: reduction in

blood platelet level, which may increase the risk of

bleeding and injuries.

Additional side effects )frequency unknown(:

Thoughts of suicide or self harm, memory

disturbances, lung-related problems )pneumonia(

Abnormal liver function tests, hepatitis )originating

from a problem in the liver or gallbladder(,

pancreatitis, muscle pain, problems with urination,

confusion, tinnitus in the ears, stuttering, anemia,

platelet deficiency, decreased levels of red blood

cells and white blood cells, unexplained bruising or

bleeding

Tendency for fractures - an increased risk of bone

fractures has been observed in patients taking

medicines belonging to this group.

Atrial fibrillation, heart failure, rapid heart rate,

pulmonary embolism, pulmonary hypertension,

stroke

Cataract, optic neuritis

Hemolytic anemia

Movement disorders developing in patients with risk

factors

QT prolongation, Torsades de pointes type

arrhythmias

Stevens-Johnson syndrome

Breast enlargement in men, breast milk secretion

unrelated to childbirth or nursing

Kidney failure, liver failure/hepatic necrosis

Violent behavior

Weakness

If a side effect occurs, if one of the side effects

worsens, or if you suffer from a side effect not

mentioned in this leaflet, consult the doctor

immediately.

Side effects can be reported to the Ministry of Health

by clicking on the link “Report Side Effects of Drug

Treatment” found on the Ministry of Health homepage

)www.health.gov.il(, that directs you to the online form

for reporting side effects.

Additionally, you can report to “Unipharm Ltd.”.

5.

HOW SHOULD THE MEDICINE BE STORED?

Avoid poisoning! This medicine, and any other

medicine, must be kept in a safe place out of the

reach and sight of children and/or infants to avoid

poisoning. Do not induce vomiting unless explicitly

instructed to do so by the doctor.

Do not use the medicine after the expiry date )exp.

date( that appears on the package. The expiry date

refers to the last day of that month.

Store the medicine at a temperature below 25°C and

in a place protected from light.

6.

FURTHER INFORMATION

In addition to the active ingredient, the medicine

also contains:

Microcrystalline cellulose, pregelatinized starch,

colloidal silicon dioxide, magnesium stearate, opadry

OY-6503 )blue(, opadry OY-6478 )yellow(.

What the medicine looks like and the contents

of the pack:

Prizma: The tablets are packaged in trays )blister( that

are inserted into a carton box.

Each package of Prizma contains 10, 15, 20, 30 or

1000 tablets. Not all package sizes may be marketed.

The tablets are film-coated, light-green, round,

biconvex, with a score line on one side.

Prizma Forte: The tablets are packaged in trays

)blister( that are inserted into a carton box.

Each package of Prizma Forte contains 14, 20, 28

or 30 tablets. Not all package sizes may be marketed.

The tablets are film-coated, green, and oblong, with a

score line on one side.

Registration holder and address: Unipharm Ltd.,

P.O.Box 21429, Tel Aviv, 6121301.

Manufacturer and address: Unipharm Ltd., “Mevo

Carmel” Industrial Park.

Registration number of the medicine in the National

Drug Registry of the Ministry of Health:

Prizma: 100 63 28423 01

Prizma Forte: 109 71 29386 01

This leaflet was checked and approved by the Ministry

of Health in April 2013 and was updated in accordance

with the Ministry of Health guidelines in July 2019.

،فاجترإ ،تاسكعنملا ديازت ،تلاضعلا بلصت ،تلاضعلا ءاخترإ )ةعاضر( ماعطلإا يف تابوعص ،فقوت نودب ءاكب ،ءوده مدع ،ةيبصع .مونلا يف تابوعصو .كعيضر ىلع رثؤي دقو ملأا بيلح يف ءاودلا اذه حرط

ي ـ عاضرلإا للاخ كعيضر ماعطلإ

انامآ رثكلأا ةقيرطلا صوصخب كبيبط يريشتسإ للاخ عاضرلإا ةلصاوم رر

ق اذإ .هتروف امزيرپ/امزيرپ لوانت ةرتف .ءاودلل يئاودلا رادقملا كبيبط للقي نأ زئاجلا نمف ،ءاودلا لامعتسإ ةرتف رثؤي دق نيتيسكوأولف نأ تاناويحلا ىدل ثاحبلأا تنيب دقل ـ ةبوصخلا ،ةبوصخلا ىلع رثؤي دق ءاودلا لوانت نإف ،

ايرظن .فاطنلا ةدوج ىلع .رشبلا ىلع ريثأتلا اذه لثم ةظحلام متت مل نكل ءاودلا اذه لامعتسإ رضي دق ـ تانكاملا لامعتساو ةقايسلا )قسانتلا( ةيكرحلا تاردقلابو ماكحلأا رادصإ ىلع ةردقلا يف ،كتظقيب ةرطخ تانكام ليغشت دنع ،ةبكرملا ةدايق دنع رذحلا يخوت بجي كلذلو .ةظقيلا مزلي طاشن لكبو ءاودلا لامعتسإ ةيفيك .3 .بيبطلا تاميلعت بسح ءاودلا لامعتسإ

امئاد بجي

اقثاو نكت مل اذإ يلديصلا وأ بيبطلا ةراشتسإ كيلع .جلاعملا بيبطلا لبق نم دد

ح امك ةددحم تاقوأ يف ءاودلا لوانت كيلع .طقف بيبطلا لبق نم ناددحي جلاعلا ةقيرطو يئاودلا رادقملا :ةداع وه يدايتعلإا يئاودلا رادقملا نأش نم .مويلل غلم 20 وه يدايتعلاا يئاودلا رادقملا ـ بائتكإ

عيباسأ 3-4 للاخ ةجاحلا بسح يئاودلا رادقملا ريغي نأ بيبطلا دح ىتح جيردتلاب يئاودلا رادقملا عفر متي دق .جلاعلا ةيادب نم متت امنيب يئاودلا رادقملا عفر بجي .مويلل غلم 80 هردق ىصقأ لاعفلا يئاودلا رادقملا ىطع

ي هنأب دكأتلل كلذو ،ةبقارملاو ةعباتملا جلاعلا ءدب دعب

اروف نسحتب رعشت لاأ زئاجلا نم .

اضافخنإ رثكلأا نسحت أرطي ىتح جلاعلا ءدب ذنم عيباسأ ةدع ر

مت ةداع .ءاودلاب .بائتكلاا ضارعأ يف يئاودلا رادقملا ـ )

Bulimia nervosa

( يبصع ماهن

.مويلل غلم 60 وه يدايتعلإا يدايتعلاا يئاودلا رادقملا ـ )OCD( يرسقلا يساوسولا بارطضلإا

اقفو يئاودلا رادقملا ريغي نأ بيبطلا نأش نم .مويلل غلم 20 وه يئاودلا رادقملا عفر متي دق .جلاعلا نم نيعوبسأ دعب ةجاحلل نسحت أرطي مل اذإ .مويلل غلم 80 هردق ىصقأ دح ىتح جيردتلاب .جلاعلا لادبتسإ بيبطلا سرديس ،عيباسأ 10 للاخ يئاودلا رادقملاو ديدش رذحب يئاودلا رادقملا عفر بجي ـ نونسملا

وه يمظعلأا يئاودلا رادقملا .غلم 40 ىتح ةداع وه يمويلا .مويلل غلم 60 تابارطضإ نم يناعت تنك اذإ ـ دبكلا فئاظو يف تابارطضإ

دق يتلا ىرخأ ةيودأ لمعتست تنك وأ دبكلل يفيظولا ءادلأا يف بيبطلا ررقي نأ زئاجلا نمف ،هتروف امزيرپ/امزيرپ ىلع رثؤت تاميلعت كل ردصي نأ وأ ،رثكأ

اضفخنم

ايئاود

ارادقم

لامعتسإب .نيموي لك ةرم هتروف امزيرپ/امزيرپ لوانتب !اهب ىصوملا ةيئاودلا ةعرجلا زواجت زوجي لا .بارشلا وأ ماعطلا نم ليلقلا ،ءاملا عم صارقلأا علب بجي

اروف هلامعتسلإ صرقلا رطش ناكملإاب ةجاحلا تعد اذإ

.صرقلا غضم وأ قحس صوصخب تامولعم رفوتت لا نم أطخلاب لفط علب اذإ وأ ةطرفم ةيئاود ةعرج تلوانت اذإ

ىفشتسملا يف ئراوطلا ةفرغل وأ بيبطلا ىلإ

لااح هجوت ،ءاودلا :لمشت ةطرفم ةيئاود ةعرجل ضارعلأا .ءاودلا ةبلع كعم رضحأو ةفيظولا يف لكاشم /سفنتلا يف تابارطضإ ،تاجنشت ،ؤيقت ،نايثغ ىتح طاشنلا طرف نيب حوارتت يكاردلإا عضولا يف تاريغتو ة

يوئرلا ،راود ،ةيبصع ،لعفلا ةدر ةلق ،يشملا يف لكاشم ،كابترإ ،ءامغإ ،تاجلاتخإ ،)ةنانع(يسنج زجع ،مدلا طغض يف عافترإ ،فاجترإ عراستم بلق مظن ـ بلقلا مظن يف تارييغت لثم بلق لكاشم ،ساع

،سوه ،ضفخنم مد طغض ،يعولا نادقف ،تاؤيقتو مظتنم ريغ وأ ةهباشم ضارعأ كلذكو فيفخ سوهو ةكرحلا يف تابارطضإ عافترإ ،نايذه لمشت يتلا )NMS( ةثيبخلا ةيبصعلا ةمزلاتملل يمونوتوأ رارقتسإ مدع ،تلاضعلا بلصت ،مسجلا ةرارح يف .ةيسفنلا ةلاحلا يف تاريغتو )

autonomic instability

لوانت بجيف بولطملا تقولا يف ءاودلا اذه لوانت تيسن اذإ

ةعرجلا لوانت دعوم ناك اذإ لاإ ،كلذب كركذت لاح ةيئاود ةعرج لوانتو ةيسنملا ةعرجلا ت

وف ةلاحلا هذه يف ،

ابيرق ةيلاتلا ةيئاودلا نكل ،يدايتعلاا دعوملا يف يلاتلا مويلا يف ةيلاتلا ةيئاودلا ةعرجلا بجي !ا

عم نيتيئاود نيتعرج لوانت لاوحلأا نم لاح يأ يف زوجي لا نع فقوتلا زوجي لا .بيبطلا ةيصوت بسح جلاعلا ىلع ةبظاوملا ىلع نسحت أرط ولو ىتح بيبطلا ةراشتسإ نودب ءاودلاب جلاعلا .ةيحصلا كتلاح نودب ئجافم لكشب ءاودلاب جلاعلا نع فقوتلا زوجي لا .ةيحصلا كتلاح ىلع نسحت أرط ولو ىتح بيبطلا ةراشتسإ وأ بيبطلا ةراشتسإ نودب ءاودلاب جلاعلا نع فقوتلا زوجي لا .يلديصلا ماطف تاملاع رهظت نأ زئاجلا نمف ،ءاودلا لوانت نع تفقوت اذإ يف تابارطضإ ؛)زخنو زخو( لمنتب روعش ،راود :لمشت يتلا روعش ؛)مونلا ىلع ةردقلا مدع ،سيباوك ،ةديدش ملاحأ( مونلا ؛قلق ،نييدايتعإ ريغ فعض وأ قاهرإ ؛ةيبصعو ةحار مدعب يفطاع رارقتسإ مدع ،كابترإ ،عادص ؛فاجترإ ؛تاؤيقت وأ نايثغ يه ءاودلا اذه نع فقوتلا دعب ماطفلا ضارعأ ،

ً

ابلاغ .قرعتو ،ماط

ُ

ف ضارعأب رعشت تنك اذإ .عيباسأ ةدع دعب يفتختو ةلدتعم دادتمإ ىلع ،يجيردت ضفخ ءارجإب ىصوي .بيبطلا ىلإ هجوت ةيلامتحا ليلقتل كلذو ،يئاودلا رادقملل ،نيعوبسأ ـ عوبسأ .ماطف ضارعأ روهظ ءاودلا عباط صيخشت بجي !ةمتعلا يف ةيودأ لوانت زوجي لا

.ءاود اهيف لوانتت ةرم لك يف ةيئاودلا ةعرجلا نم دكأتلاو .كلذ رملأا مزل اذإ ةيبطلا تاراظنلا عض رشتسإ ،ءاودلا لامعتسإ لوح ةيفاضإ ةلئسأ كيدل ترفوت اذإ

.يلديصلا وأ بيبطلا ةيبناجلا ضارعلأا .4

اضارعأ ببسي دق هتروف امزيرپ/امزيرپ لامعتسإ نإ ،ءاود لكب امك .ةيبناجلا ضارعلأا ةمئاق نم شهدنت لا .نيلمعتسملا ضعب دنع ةيبناج .اهنم

ايأ يناعت لاأ زئاجلا نم ىفشتسملا ىلإ وأ بيبطلا ىلإ هجوتلاو جلاعلا نع فقوتلا بجي

:

ً

اروف خافتنإ ،ةكح ،حفط لمشي يذلا ،يسسحت لعف در ثودح لاح يف رارمحإ ،سفنتلا يف تابوعص وأ ،نينيعلا ،ناسللا ،نيتفشلا ،هجولا ةنوخس نايحلأا ضعب يفو دلجلا رشقت وأ تلاصيوح روهظ ،دلجلا

اضيأ لصافملا يف ملاآ وأ .راحتنلإا وأ كسفنل ىذلأا قاحلإ لوح راكفأ كيدل تدجو اذإ

:اذإ بيبطلا ىلإ هجوتلا بجي فوقولا وأ سولجلا ىلع

ارداق تسلو ءوده ةلق نم يساقت تنك

akathisia

( مات لكشب ةعومجم - نينوتوريسلا ةمزلاتم نم نوجلاعتملا ضعب يساقي دق تارييغت ،عيرس ضبن وأ عيرس سفنت :لمشت يتلا ضارعلأا نم ،مونلل ليم ،ةيبصع ،نايذه ،كابترإ ،ءوده مدع( ةيسفنلا ةلاحلا يف ،مسجلا ةرارح عافترإ ،دروت ،راود ،نزاوتم ريغ مد طغض ،)ةبوبيغ مدع ،تلاضعلا بلصت/يوق ضابقنإ وأ فاجترإ ،قرعت طرف زاهجلا يف ضارعأ وأ/و تاجلاتخإ ،تاسكعنملا ديازت ،قسانتلا .)ردان( )لاهسإ ،ؤيقت ،نايثغ( يمضهلا نينسملا نيجلاعتملا ىدل ةصاخ ،كابترإ وأ راود ،فعضب روعش .لوبلل ةردم ةيودأب نيجلاعتملا ىدلو .ناديدش ةيبصعو طخس بلق مظنب ىلجتت ضارعلأا .بلقلل يئابرهكلا طاشنلا يف تاريغت دنع راود ،ءامغإو راود ،ةيسفنت ةقئاض ،عيرس ،ءيطب ،مظتنم ريغ .سولجلا وأ ءاقلتسلإا ةيعضو نم ضوهنلا .يمضهلا زاهجلا يف ةفزنأ ،ةيومد ةفزنأ ،فاعر :لثم ةفزنأ

.)ةدعابتم تاقوأ يف رهظت( جلاتخإ تابون داح عافترإب ىلجتت يتلا )ةدعابتم تاقوأ يف رهظت( سوه تابون ،روهتم كولس ،مونلا يف ةديدش تابارطضإ ،ةقاطلا ىوتسم يف .عيرس ملاك ،ةقارب راكفأ ،امهيف غلابم ةحار ةلق وأ حرف .)ردان(

)hepatitis(

دبكلا باهتلإ

.)ردان( يركذلا بيضقلل ملؤمو لصاوتم باصتنإ

ىدل يساسأ لكشب رهظي ،ردان( مدلا يف مويدوصلا ةبسن ضافخنإ

يذلا تابث مدعب روعش وأ فعض ،عادصب لثمتي يذلا )نينسملا يف لكاشم ،زيكرتلا يف ةبوعص ،كابترإ ،تاطوقس ىلإ يدؤي دق نادقف ،تاجلاتخإ ،تاءامغإ ،نايذه :ةريطخ تلااح يفو ةركاذلا .تومو سفنتلا عاطقنإ ،يعولا ةديدش ةكحو تلاصيوح روهظو دلجلا رارمحإ لمشت ةيدلج ضارعأ

toxic epidermal – يدلج رخنو نوسنوج سنيڤيتس ةمزلاتم(

.)necrolysis

:لمشت ،ةريطخ ةيبناج

اضارعأ هتروف امزيرپ/امزيرپ ببسي دق نيذلا نيجلاعتملا نإ ،مدلا يف ركسلا بسن ىلع ةرطيسلا يف لكاشم نم نوناعي دق هتروف امزيرپ/امزيرپ نولوانتيو يركس مهيدل امزيرپ/امزيرپ لوانت ةرتف للاخ ركسلا بسن ضافخنلإ لكاشم فقوتلا دنع ركسلا بسن يف عافترإ ثدحي نأ زئاجلا نم .هتروف يئاودلا رادقملا رييغت ىلإ كبيبط جاتحي نأ زئاجلا نم .جلاعلا نع /امزيرپ نع فقوتلا وأ ءدب دنع كلذو كب ةصاخلا يركسلا ةيودلأ .هتروف امزيرپ .مونلا يف تابارطضإ وأ قلقب روعشلا

امزيرپ/امزيرپ نولوانتي نيجلاعتم ىدل ةعئاش ةيبناج ضارعأ :لمشت ،هتروف ةيدايتعإ ريغ ملاحأ

يسنجلا يفيظولا ءادلأا يف لكاشم وأ فعض ،ؤيقت وأ نايثغ ،ةيمضه لكاشم ،لاهسإ ،ةيهشلا نادقف مفلا يف فافج ازنإولفنإ ضارعأ

قاهرإب روعش مونلا تاداع يف تاريغت بؤاثت ةرجنحلا يف ملأ وأ ةيفنلأا بويجلاب ثولت فاجترإ

قرعت ةيبصعو قلقلاب روعش رح تابه حفط :لمشت نيقهارملاو لافطلأا ىدل ىرخأ ةيبناج ضارعأ شطعلا ديازت ةحار ةلقب روعشو لضعلا ةكرح يف ةيدايتعإ ريغ ةدايز فاعر ةبراقتم تاقوأ يف لوبتلا

رثكأ ةديدش ةيرهش ةرود بجي .مسجلا نزوبو ومنلا ةريتو يف ضافخنإ ثودح زئاجلا نم امزيرپ/امزيرپ ـب جلاعلا ةرتف للاخ كلفط نزوو لوط ةبقارم .هتروف :ةبراقتم تاقوأ يف رهظت يتلا ةيبناج ضارعأ مفلا يف فافج نزولا نادقف ،كاسمإ ،لاهسإ

هجولا يف رارمحإو ةنوخس عادص ةبغرلاب ضافخنإ ،يسفن رارقتسإ مدع ،قرأ ،مونلا يف لكاشم ةيسنجلا ةوشنلا ىلإ لوصولا ىلع ةردقلا مدع وأ ةبوعص ،ةيسنجلا قوذتلا ةساح يف ريغت لومخ ،مونلل ليم ةيؤرلا يف لكاشم زيكرتلا يف يندت لصافملا يف ملاآ

رركتم لكشب لوبتلا كلذ يف امب لوبتلا يف لكاشم راود ،ةريرعشق QT عطقم ةلاطإ كلذ يف امب ةمظتنم ريغ وأ/و ةيوق بلق تاضبن ببسلا لوهجم يلبهم فيزن :ةدعابتم تاقوأ يف رهظت يتلا ةيبناج ضارعأ ةقسانتم ريغ تاكرح ،)

akathisia

( يكرحلا ءودهلا مدع ةيدارإ لا تاكرح ،)

ataxia

نيتقدحلا عسوت مدلا طغض ضافخنإ ،بلقلا مظن يف تابارطضإ

ةحرق ،دوسأ زارب ،يمضهلا زاهجلا يف باهتلإ ،علبلا يف بارطضإ

ةدعملا يف

purpura

( حفطلا هبشت يتلا ةريغص ةيومد ةفزنأ

،ةيسنجلا ةبغرلا يف ةدايز ،نانسلأا لكآت ،نزاوتلا يف بارطضإ

داح روعش ،)ةيصخشلا ددبت( "تاذلا نع لاصفنلاا" بارطضإ يئلايخ لعف در ،يلضعلا رتوتلا ديازت ،ةداعسلاب رعشلا طقاست لوبتلا دنع ةقرح وأ ملأ

راحتنلإا ةلواحم نينذلأا يف نينط :ةردان تاقوأ يف رهظت يتلا ةيبناج ضارعأ ،قنعلل عيرس خافتنإ ،ةيومد ةيعوأ باهتلإ ،تاجنشت ،رعذ تابون ،سمشلا ءوضل ةيساسح ،ءيرملا يف ملأ ؛ةرجنحلا وأ/و مفلا ،هجولا مدلا نيتكلاورپ طرف ةفزنأ ثودحل ةروطخلا ةدايز ،)مد ؤيقت ،يومد لاهسإ لمشت ضارعأ( يمضهلا زاهجلا يف فزن

يف ةحرق ،ءاعملأا يف ةحرق لثم( يمضهلا زاهجلا يف تاحرقت )ةفزان ةيدعم ةحرق ،ةيمضه ةحرق ،ءيرملا ةرجنحلا يف ةمذو ،ةيومدلا تاحيفصلا بسن يف ضافخنإ :

ً

ادج ةردان تاقوأ يف رهظت .تاباصإو فزنل ةروطخلا ديازت ىلإ يدؤي دق يذلا :)فورعم ريغ اهعويش( ةيفاضإ ةيبناج ضارعأ يف تابارطضإ ،سفنلاب ىذلأا قاحلإ نع وأ راحتنلإا لوح راكفأ

)نيتئرلا باهتلإ( نيتئرلاب قلعتت لكاشم ،ةركاذلا ةلكشم هردصم يذلا( ناقري ،دبكلا فئاظو تاصوحف يف للخ يف ملاآ ،سايركنبلا يف باهتلإ ،)ةرارملا سيك يف وأ دبكلا يف ،مثعلت ،نينذلأا يف نينط ،كابترإ ،لوبتلا يف لكاشم ،تلاضعلا ايلاخ بسن يف ضافخنإ ،ةيومدلا تاحيفصلا يف صقن ،مدلا رقف .ببسلا ةلوهجم ةفزنأ وأ تامدك ،ءاضيبلا مدلا ايلاخو ءارمحلا مدلا ماظعلا يف روسك ثودحل ةروطخلا ةدايز ـ روسك ثودحل ليم .ةعومجملا هذهل يمتنت ةيودأ نولوانتي نيذلا نيجلاعتملا ىدل تظحول طرف ،يوئر مامصنإ ،عيرس بلق مظن ،ةيبلق ةتكس ،ينيذأ نافجر ةيغامد ةتكس ،يوئرلا مدلا طغض رصبلا بصع يف باهتلا ،تكاراتاك يللاحنلإا مدلا رقف لماوع مهيدل نيجلاعتم ىدل روطتت يتلا ةكرحلا يف تابارطضإ

ةروطخ Torsades de pointes :عون نم مظن تابارطضإ ،QT ةلاطإ

نوسنوج سنڤيتس ةمزلاتم ةقلاع نود يدثلا نم بيلح زارفإ ،لاجرلا ىدل نييدثلا مخضت عاضرلإ وأ ةدلاول يدبك رخن/لشف ،يولك لشف فينع كولس فعض وأ ةيبناجلا ضارعلأا ىدحإ تمقافت اذإ ،يبناج ضرع رهظ اذإ كيلع ،ةرشنلا هذه يف ركذي مل يبناج ضرع نم يناعت امدنع

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لااح بيبطلا ةراشتسإ ىلع طغضلا ةطساوب ةحصلا ةرازول ةيبناج ضارعأ نع غيلبتلا ناكملإاب ىلع دوجوملا »يئاود جلاع بقع ةيبناج ضارعأ نع غيلبت« طبارلا )www.health.gov.il( ةحصلا ةرازو عقومل ةيسيئرلا ةحفصلا .ةيبناج ضارعأ نع غيلبتلل رشابملا جذومنلا ىلإ كهجوي يذلا ."ض.م مرافينوي" ةكرش غيلبت ناكملإاب ،كلذل ةفاضلإاب ؟ءاودلا نيزخت ةيفيك .5 قلغم ناكم يف رخآ ءاود لكو ءاودلا اذه ظفح بجي !ممستلا بنجت كلذو عضرلا وأ/و لافطلأا ةيؤر لاجمو يديأ لوانتم نع

اديعب ةحيرص تاميلعت نودب ؤيقتلا ببست لا .ممستلاب مهتباصإ يدافتل .بيبطلا نم )exp. date( ةيحلاصلا خيرات ءاضقنإ دعب ءاودلا لامعتسإ زوجي لا

ريخلأا مويلا ىلإ ةيحلاصلا خيرات ريشي .ةبلعلا رهظ ىلع رهظي يذلا .رهشلا سفن نم يفو ةيوئم ةجرد 25 نود ةرارح ةجردب ءاودلا نيزخت بجي .ءوضلا نم يمحم ناكم ةيفاضإ تامولعم .6

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اضيأ ةلاعفلا ةداملل ةفاضلإاب ءاودلا يوتحي

Microcrystalline cellulose, pregelatinized starch,

colloidal silicon dioxide, magnesium stearate,

opadry OY-6503 )blue(, opadry OY-6478 )yellow(.

:ةبلعلا ىوتحم وه امو ءاودلا ودبي فيك .نوترك ةبلع لخاد )رتسيلب( تاحيول نمض ةأبعم صارقلأا :امزيرپ .صرق 1000 وأ 30 ،20 ،15 ،10 دجوي امزيرپ ةبلع لك يف .بلعلا ماجحأ ةفاك ق

وست لاأ زئاجلا نم رطشلل طخ عم نيبناجلا لاك نم ةبدحم ،ةريدتسم ،ةيلطم صارقلأا .حتاف رضخأ اهنول ،دحاو بناج نم ةبلع لخاد )رتسيلب( تاحيول نمض ةأبعم صارقلأا :هتروف امزيرپ .نوترك

اصرق 30 وأ 28 ،20 ،14 دجوي هتروف امزيرپ ةبلع لك يف .بلعلا ماجحأ ةفاك ق

وست لاأ زئاجلا نم .رضخأ اهنول ،دحاو بناج نم رطشلل طخ عم ،ةلواطم ،ةيلطم صارقلأا ،بيبأ ـ لت 21429 .ب.ص ،.ض.م مرافينوي :هناونعو زايتملإا بحاص

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."لمرك وڤام" ةعانصلا كراپ ،.ض.م مرافينوي :هناونعو جتنملا مسإ :ةحصلا ةرازو يف يموكحلا ةيودلأا لجس يف ءاودلا لجس مقر

100 63 28423 01

:امزيرپ

109 71 29386 01

:هتروف امزيرپ ةغيصب ةرشنلا هذه ةغايص تمت ،ةءارقلا نيوهتو ةلوهس لجأ نم .نيسنجلا لاكل صصخم ءاودلا نإف ،كلذ نم مغرلا ىلع .ركذملا خيرات يف ةحصلا ةرازو لبق نم تصخ

رو تصح

ف ةرشنلا هذه خيراتب ةحصلا ةرازو تاميلعت بجومب اهثيدحت متو 2013 ناسين .2019 زومت