POR-8 Ferring

Country: Australia

Language: English

Source: Department of Health (Therapeutic Goods Administration)

Active ingredient:

Ornipressin

Available from:

Ferring Pharmaceuticals Pty Ltd

Class:

Medicine Registered

Patient Information leaflet

POR-8 FERRING
®

INJECTION
_Ornipressin_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about POR-8 FERRING.
It does not contain all the available
information. It does not take the
place of talking to your doctor or
pharmacist.
Please read this leaflet before
treatment with POR-8 FERRING is
commenced.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using POR-8
FERRING against the benefits they
expect it will have for you.
If you have any concerns about using
this medicine, ask your doctor or
pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
WHAT POR-8 FERRING
IS USED FOR
This medicine is used to help control
bleeding. It narrows blood vessels at
the site of an operation.
Ask your doctor if you have any
questions about why this medicine
has been prescribed for you. Your
doctor may have prescribed it for
another reason.
There is no evidence that POR-8
FERRING medicine is addictive.
It is available only with a doctor's
prescription.
BEFORE YOU USE POR-8
FERRING
_WHEN YOU MUST NOT USE IT_
Do not use POR-8 FERRING if you
have/are:
•
coronary heart disease
•
very high blood pressure
•
epilepsy
•
advanced hardening of the
arteries
•
infection relating to pregnancy
•
pregnant
•
allergies to the contents of the
product
There are some anaesthetic
procedures where POR-8 FERRING
should not be used.
Your doctor has more information
about these.
Do not use this medicine after the
expiry date printed on the pack or if
the packaging is torn or shows signs
of tampering.
If it has expired or is damaged, return
it to your pharmacist for disposal.
_BEFORE YOU START TO USE IT_
Tell your doctor if you have or have
had any of the medical conditions
listed above or if you have a
condition in which a rise in blood
pressure may cause you to become
unwell.
Tell your doctor if you plan to
become pregnant
_USING OTHER MEDICINES_
Tell your doctor or pharmacist if you
are using any other medicines,
inclu

Summary of Product characteristics

#1196-v5A 

PRODUCT INFORMATION 

POR-8 FERRING
®

Ornipressin 

DESCRIPTION 
POR-8 FERRING
®
 is ornipressin (8-ornithine-vasopressin), a
synthetic polypeptide 
with a molecular weight of 1042.2.  It is closely related to
synthetic vasopressin, 
and differs from that substance only by the substitution
of ornithine for lysine in the 
side chain. It is available in sealed 1mL ampoules each
containing 5 IU.  The 
sterile solution is clear and pH is adjusted to 3.7. 

POR-8
FERRING contains sodium acetate, sodium chloride, acetic acid
and water 
for injections as excipients. 

Cys-Try-Phe-Gln-Asn-Cys-Pro-Orn-Gly-NH
2

C
45
H
63
N
13
O
12
S
2 

CAS No. 3397-23-7 

PHARMACOLOGY 
POR-8 FERRING
®
 has a potent and specific constrictor effect on the 
microcirculation and veins which
is equal to, if not greater than, that of 
vasopressin. 
It has antidiuretic activity but this is weak by comparison
with 
vasopressin. 

Topical administration or infiltration leads within
10 minutes to local ischaemia 
which usually lasts for 1 to 2 hours, and is not followed
by reactive hyperaemia. 

POR-8 FERRING
®
 may be used with general anaesthetics which are usually not 
compatible with
adrenaline, eg halothane, without fear of precipitating cardiac 
arrhythmias. 
#1196-v5A 

INDICATIONS 
LOCAL ADMINISTRATION: to induce ischaemia and
haemostasis at the site of an 
operation in various types of surgery where
bleeding is a problem. 

PLASTIC SURGERY: Hair transplants, meloplasty, otoplasty, skin
grafts, resection of 
tumours etc. 

OBSTETRICS/GYNAECOLOGY: Vaginal repair, vaginal hysterectomy, cone
biopsy of 
cervix, episiotomy, myomectomy. 

ENT
SURGERY: Tonsillectomy, submucous resection of septum, myringoplasty etc. 

OTHER TYPES OF SURGERY: Neurosurgery, orofacial surgery, surgery of head
and 
neck,�