Country: Indonesia
Language: Indonesian
Source: Badan Pengawas Obat dan Makanan RI - Indonesian Food and Drug Supervisory Agency
PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 3, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 4, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 6B, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 7F, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 8, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYP
ORGANON PHARMA INDONESIA TBK - Indonesia
PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 3, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 4, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 6B, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 7F, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYPE 8, PNEUMOCOCCAL POLYSACCHARIDE DANISH TYP
25 MCG/DOSE /25 MCG/DOSE /25 MCG/DOSE /25 MCG/DOSE /25 MCG/DOSE /25 MCG/DOSE /25 MCG/DOSE /25 MCG/DO
INJEKSI
DUS, 10 PRE-FILLED SYRINGE @ 0.5 ML
MERCK SHARP & DOHME CORP. - United States of America
2021-07-17
_ _ PNEUMOVAX 23 (PNEUMOCOCCAL VACCINE POLYVALENT) INJECTION PNEUMOVAX 23 (pneumococcal vaccine polyvalent), is a sterile, liquid vaccine for intramuscular or subcutaneous injection. It consists of a mixture of highly purified capsular polysaccharides from the 23 most prevalent or invasive pneumococcal types of Streptococcus pneumoniae , including the six serotypes that most frequently cause invasive drug-resistant pneumococcal infections among adults in the United States (see Table 1). The 23-valent vaccine accounts for at least 90% of pneumococcal blood isolates and at least 85% of all pneumococcal isolates from sites which are generally sterile as determined by ongoing surveillance of United States data. PNEUMOVAX 23 is manufactured according to methods developed by the MERCK RESEARCH LABORATORIES. Each 0.5 mL dose of vaccine contains 25mcg of each polysaccharide type dissolved in isotonic saline solution containing 0.25% phenol as a preservative. CLINICAL PHARMACOLOGY Pneumococcal infection is a major cause of pneumonia, bacteremia, meningitis, and otitis media. Strains of drug-resistant S. pneumoniae have become increasingly common in the United States and in other parts of the world. In some areas as many as 35% of pneumococcal isolates have been reported to be resistant to penicillin. Many penicillin-resistant pneumococci are also resistant to other antimicrobial drugs (e.g., erythromycin, trimethoprim-sulfamethoxazole and extended-spectrum cephalosporins), therefore emphasizing the importance of vaccine prophylaxis against pneumococcal disease. Disetujui Oleh BPOM : 07/11/2023 ID : EREG100373VR12300322 _ _ Epidemiology Pneumococcal infection causes approximately 40,000 deaths annually in the United States. At least 500,000 cases of pneumococcal pneumonia are estimated to occur annually in the United States; S. pneumoniae accounts for approximately 25%-35% of cases of community-acquired bacterial pneumonia in persons who require hospitalization. Pneumococcal disease accounts for an estimated 50,000 cases o Read the complete document