PACOFEN TABLETS

Country: Singapore

Language: English

Source: HSA (Health Sciences Authority)

Active ingredient:

Caffeine Anhydrous; Codeine Phosphate; Paracetamol

Available from:

TEVA PHARMACEUTICAL INVESTMENTS SINGAPORE PTE. LTD.

ATC code:

N02BE51

Dosage:

30 mg

Pharmaceutical form:

TABLET

Composition:

Caffeine Anhydrous 30 mg; Codeine Phosphate 8 mg; Paracetamol 500 mg

Administration route:

ORAL

Prescription type:

Pharmacy Only

Manufactured by:

BEACONS PHARMACEUTICALS PTE. LTD.

Authorization status:

ACTIVE

Authorization date:

1991-05-07

Patient Information leaflet

3
16.11.2021
KM
15.12.2021
KM
104x171 mm
Beacons Pharmaceuticals Pte Ltd
8pt
16.11.2021
1.
2.
3.
1. black
2.
3.
4.
5.
6.
AAAN9268 - Paracetamol/Caffeine/Codeine 500/30/8 mg -, PIL, Singapore
PACOFEN TABLETS
DESCRIPTION:
Strawberry Pink, 13.0 mm diameter, round, flat tablets.
COMPOSITION:
Paracetamol BP 500mg/tab
Caffeine BP 30mg/tab
Codeine Phosphate BP 8mg/tab
PHARMACOLOGY:
Pacofen contains Paracetamol, caffeine anhydrous and codeine
phosphate.
1) Paracetamol has analgesic and antipyretic effects. It inhibits the
prostaglandin synthesis in the brain to relieve pain of moderate
intensity. It reduces fever by a direct effect on the heat-regulation
centre
to increase dissipation of body heat
2) Caffeine acts on the CNS to produce a condition of wakefulness and
increase mental activity.
3) Ingestion of codeine phosphate produces peak plasma-codeine
concentration in about one hour.
Codeine is metabolised by 0- and N· demethylation in the liver to
morphine and norcodeine.
Codeine and its metabolites are excreted almost entirely by the
kidney,
mainly as conjugates with glucuronic acid.
INDICATIONS:
For relief of aches and pain e.g., headache, toothache and
dysmenorrhoea.
Codeine is not recommended for the treatment of post-operative pain
following surgical procedures such as tonsillectomy or adenoidectomy
in
children and adolesoents below 18 years old due to the increased risk
of
respiratory depression.
DOSAGE:
ADULTS: 1-2 tablets
These doses may be given 3-4 trnes dally as required (Max. 6 tablets a
day).
CHILDREN AND ADOLESCENTS
Codeine should not be used in children below 12 years old. In those 12
years; old and above, codeine may be used for the short-term treatment
of
acute moderate pain which is not relieved by analgesics such as
Ibuprofen
or paracetamol alone. The lowest effective dose should be used for the
shortest possible duration.
PRECAUTION _I _WARNING:
This preparation contains PARACETAMOL. Do not take any other
PARACETAMOL containing medicines at the same time. Inappropriate use
of product containing pa

Summary of Product characteristics

108219_S1 - P: Paracetamol, Caffeine, Codeine Phosphate (Pacofen) SG,
Tablets 500mg, 30mg, 8mg, SmPC
01
12.07.2023
MT
104x171 mm
Beacons Pharmaceuticals Pte.
8 pt
Black
PACOFEN TABLETS
DESCRIPTION:
Strawberry Pink, 13.0 mm diameter, round, flat tablets.
COMPOSITION:
Paracetamol BP 500mg/tab
Caffeine BP 30mg/tab
Codeine Phosphate BP 8mg/tab
PHARMACOLOGY:
Pacofen contains Paracetamol, caffeine anhydrous and codeine
phosphate.
1) Paracetamol has analgesic and antipyretic effects. It inhibits the
prostaglandin synthesis in the brain to relieve pain of moderate
intensity. It reduces fever by a direct effect on the heat-regulation
centre
to increase dissipation of body heat
2) Caffeine acts on the CNS to produce a condition of wakefulness and
increase mental activity.
3) Ingestion of codeine phosphate produces peak plasma-codeine
concentration in about one hour.
Codeine is metabolised by 0- and N· demethylation in the liver to
morphine and norcodeine.
Codeine and its metabolites are excreted almost entirely by the
kidney,
mainly as conjugates with glucuronic acid.
INDICATIONS:
For relief of aches and pain e.g., headache, toothache and
dysmenorrhoea.
Codeine is not recommended for the treatment of post-operative pain
following surgical procedures such as tonsillectomy or adenoidectomy
in
children and adolesoents below 18 years old due to the increased risk
of
respiratory depression.
DOSAGE:
ADULTS: 1-2 tablets
These doses may be given 3-4 trnes dally as required (Max. 6 tablets a
day).
CHILDREN AND ADOLESCENTS
Codeine should not be used in children below 12 years old. In those 12
years; old and above, codeine may be used for the short-term treatment
of
acute moderate pain which is not relieved by analgesics such as
Ibuprofen
or paracetamol alone. The lowest effective dose should be used for the
shortest possible duration.
PRECAUTION _I _WARNING:
This preparation contains PARACETAMOL. Do not take any other
PARACETAMOL containing medicines at the same time. Inappropriate use
of product containing paracetamol can result i