OTSU-D1015NS 0.18% SODIUM CHLORIDE AND 10% DEXTROSE INTRAVENOUS INFUSION B.P

Country: Malaysia

Language: English

Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Active ingredient:

Glucose anhydrous; SODIUM CHLORIDE (SALT)

Available from:

LUEN WAH MEDICAL CO. SDN. BHD.

INN (International Name):

Glucose anhydrous; SODIUM CHLORIDE (SALT)

Units in package:

500ml mL

Manufactured by:

PT OTSUKA (INDONESIA)

Summary of Product characteristics

OTSU-D10,1/5NS 0.18% SODIUM
CHLORIDE AND 10% GLUCOSE
INTRAVENOUS INFUSION B.P.
COMPOSITION:
Each 500mL solution contains 0.90 g Sodium Chloride and 50.00 g
Anhydrous Dextrose.
DESCRIPTION:
Clear, colorless, sterile and pyrogen free solution.
INDICATION:
As an intravenous supply of nutrition, sodium and chloride
electrolytes in
the blood.
DRUG ACTION:
Dextrose and Sodium Chloride injection have value as a source of
water, electrolytes and calories. They are capable of inducing
diuresis
depending of the clinical conditions of patient.
DOSAGE:
Intravenous administration, the dosage depending on the patients
condition individually. As directed by a physician
SYMPTOMS AND TREATMENT FOR OVERDOSAGE AND
ANTIDOTE (S):
-
Infusion of dextrose much above 800 mg per kg body weight per
hour, dextrose will appear in the urine, causing hyperglycemia.
-
Large does will cause accumulation and edema, hypokalemia-
Antidote: Insulin injection
WARNING:
-
Dextrose and Sodium Chloride Injection should be used with great
care. If at all, in patients with congestive heart failure, severe
renal
insufficiency, and in clinical states in which there exists oedema
with sodium retention.
-
Dextrose Injection with low electrolyte concentrations should not be
administered
simultaneously
with
blood
through
the
same
administration set because of the possibility of pseudo agglutination
or hemolysis. The container label for those injections bears the
statement: Do not administer simultaneously with blood.
-
The intravenous administration of Dextrose and Sodium Chloride
Injection can cause fluid and/or solute over loading resulting in
dilution
of
serum
electrolyte
concentration,
over
hydration,
congested states, or pulmonary oedema. The risk of dilutional
states is inversely proportional to the electrolyte concentration of
the injection. The risks of solute overload causing congested states
with peripheral and pulmonary oedema. It's directly proportional to
the electrolyte concentrations of the injections.
-
Excessive
administration
of
Dextrose
and
So