NORIT CARBOMIX GRANULES (Activated Charcoal 5g in 6.15g)

Country: Malaysia

Language: English

Source: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Active ingredient:

ACTIVATED CHARCOAL

Available from:

RX PHARMA SDN BHD

INN (International Name):

ACTIVATED CHARCOAL

Units in package:

61.5 gm

Manufactured by:

Cabot Norit Nederland B.V.

Patient Information leaflet

FOR HOSPITAL USE ONLY

Summary of Product characteristics

NORIT CARBOMIX
GRANULES
(ACTIVATED CHARCOAL)
NORIT CARBOMIX, granulate for suspension is a
fine,
black
granules,
relatively
uniform
in
size,
without taste or odour.
COMPOSITION:
Each 5g Activated Charcoal as active ingredient,
has
an
excipients
of
Citric
Acid
0.15g,
Acaciae
gummi 0.5g and Glycerol 0.5g.
PHARMACODYNAMIC PROPERTIES:
Activated
charcoal
is
a
specifically
carbonized
material of a botanical origin with a large internal
surface, which can adsorb harmful or undesirable
substances in the gastrointestinal tract.
In case of intoxications the activated charcoal can
be used to adsorb the active ingredients from the
gastrointestinal tract.
The adsorption of a partly absorbed active ingredient
to
activated
charcoal
will
cause
a
concentration
gradient
between
circulating
plasma
and
bowel
contents. Therefore passively absorbed substances
can diffuse in the opposite direction again to the
intestines.
Thus
a
repeated
administration
of
activated
charcoal
can
be
effective,
even
after
absorption of an active ingredient
PHARMACOKINETIC PROPERTIES:
Since activated charcoal is not absorbed from the
gastro intestinal tract, there is no distribution phase
nor
any
metabolism.
The
complex
between
activated carbon and the adsorbed compounds
will
be completely passed out in the stool.
INDICATIONS:
For acute oral poisoning of toxins and overdose of
medication.
DOSAGE & METHOD OF ADMINISTRATION
_Adult and children from 12 years of age: _
50-100g Activated Charcoal, to be administered as
soon as possible. In case of serious poisoning, the
treatment
should,
during
a
number
of
days,
be
followed by a repeated dose of 20g every 4-6 hours
(20g Activated Charcoal equals approximately 160
ml of the reconstituted suspension). In unconscious
patients,
a
doctor
or
nurse
under
medical
supervision,
should
administer
the
suspension
through a stomach tube.
NORIT
CARBOMIX
can
also
be
administered
after
vomiting or gastric lavage.
_Children up to 12 years of age: _
Recommended
dosage:
about
1g
activated
charcoal per kg body weight. In case of ac