METRELEPTIN for subcutaneous Injection 11.25mg [SHIONOGI] (メトレレプチン皮下注用11.25mg「シオノギ」)

Country: Japan

Language: English

Source: すりの適正使用協議会 RAD-AR Council, Japan

Active ingredient:

Metreleptin (genetical recombination)

Available from:

Shionogi & Co., Ltd.

INN (International Name):

Metreleptin (genetical recombination)

Pharmaceutical form:

white and clumped injectable preparation

Patient Information leaflet

Drug Information Sheet("Kusuri-no-Shiori")
Self-injection
Published: 07/2013
The information on this sheet is based on approvals granted by the
Japanese regulatory authority. Approval
details may vary by country. Medicines have adverse reactions (risks)
as well as efficacies (benefits). It is
important to minimize adverse reactions and maximize efficacy. To
obtain a better therapeutic response,
patients should understand their medication and cooperate with the
treatment.
BRAND NAME:
METRELEPTIN FOR SUBCUTANEOUS INJECTION
11.25MG [SHIONOGI]
ACTIVE INGREDIENT:
Metreleptin (genetical recombination)
DOSAGE FORM:
white and clumped injectable preparation
IMPRINT OR PRINT ON WRAPPING:
EFFECTS OF THIS MEDICINE
Leptin is one of the hormones secreted from fatty tissues, and it
shows an inhibitory effect on
food intake and enhancing effect on energy comsumption and on
sensitivity of insulin. This
medicine enhances sugar and/or lipid metabolism by covering the action
of leptin.
It is usually used for the treatment of lipodystropy.
THE FOLLOWING PATIENTS MAY NEED TO BE CAREFUL WHEN USING THIS
MEDICINE.BE SURE TO TELL YOUR DOCTOR
AND PHARMACIST.
・If you have previously experienced any allergic reactions (itch,
rash, etc.) to any medicines
or foods.
・If you are pregnant or breastfeeding.
・If you are taking any other medicinal products. (Some medicines may
interact to enhance or
diminish medicinal effects. Beware of over-the-counter medicines and
dietary supplements
as well as other prescription medicines.)
DOSING SCHEDULE (HOW TO TAKE THIS MEDICINE)
・
Your dosing schedule prescribed by your doctor is((         

to be written by a healthcare
professional
))
・This medicine can be used after dissolving in water for injection.
In general, 0.04 mg as the active ingredient per 1 kg of body weight
for male, 0.06 mg for
female aged under 18 years old, or 0.08 mg for female aged 18 years
old or more is
administered by a subcutaneous injection once daily. The initial dose
is 0.02 mg, 0.03 mg or